RecruitingNot ApplicableNCT07822633

Inter-Limb Transfer in Acute Stroke

Identifying Brain Regions Critical for Human Motor Learning Through Anatomic-functional Correlations of Deficits in Acute Stroke: Integrated Robotic and Voxel-based Lesion Symptom Mapping Approach


Sponsor

University Hospital of Mont-Godinne

Enrollment

250 participants

Start Date

Aug 11, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

This study aims to investigate whether the improvements achieved through motor skill learning (MSkL) with the ipsilesional upper limb (UL) are transferred to the contralesional UL during the (sub)acute stroke phase, and to identify the neural substrates underlying this inter-limb transfer. To achieve this, healthy individuals, acute and chronic stroke patients will perform proximal and distal MSkL tasks using serious games implemented on robotic devices. This will be complemented by behavioural assessments and multimodal MRI.


Eligibility

Min Age: 40 YearsMax Age: 90 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a medical device called Dextrain Manipulandum®, a medical device called Dextrain Manipulandum®, and others for people with chronic stroke patients, healthy individuals (controls), and other related conditions. The study is currently recruiting participants at 2 locations. People eligible for this study include aged 40 Years to 90 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICEREAplan®

motor skill learning with the REAplan® rehabilitation robot, to be performed with ipsilesional arm

DEVICEDextrain Manipulandum®

motor skill learning with the Dextrain Manipulandum® dexterity tool to be performed with ipsilesional hand

DEVICEREAplan®

proximal motor control and motor skill assessement with the REAplan® rehabilitation robot, to be performed by each arm

DEVICEDextrain Manipulandum®

distal motor skill assessment with the Dextrain Manipulandum® dexterity tool to be performed by each hand


Locations(2)

CHU UCL Namur

Yvoir, Namur, Belgium

Cliniques universitaires Saint-Luc

Brussels, Belgium

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NCT07822633


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