RecruitingNCT07824479

Predicting Efficacy of Preoperative Immunotherapy in Advanced Gastric Cancer

Predicting Efficacy of Preoperative Immunotherapy Combined Treatment in Advanced Gastric Cancer


Sponsor

Ruijin Hospital

Enrollment

120 participants

Start Date

Jun 17, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

This study intends to employ FAPI and Grazytracer PET/CT to predict the therapeutic response to preoperative immunotherapy-based combination regimens in patients with advanced gastric cancer. The study is expected to provide an early, non-invasive predictive tool for immunotherapy-based combination therapy in gastric cancer, offer molecular imaging-based evidence for treatment stratification, and facilitate the optimization of precision therapeutic strategies.


Eligibility

Min Age: 18 YearsMax Age: 80 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying FAPI PET/CT Imaging and Grazytracer PET/CT Imaging for people with advanced gastric cancer. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years to 80 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIAGNOSTIC_TESTFAPI PET/CT Imaging

A FAP-targeted radiotracer for PET/CT imaging; administered intravenously.

DIAGNOSTIC_TESTGrazytracer PET/CT Imaging

A Granzyme B-targeted radiotracer for PET/CT imaging; administered intravenously.


Locations(1)

Ruijin Hospital, Shanghai Jiao Tong University School of Medicine

Shanghai, China

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NCT07824479


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