RecruitingPhase 2Phase 3NCT07824674

The Effect of Additive On-Demand Sildenafil vs. Dextrose Candy on Maximum Exercise Capacity in Pulmonary Arterial Hypertension

The Effect of Additive On-Demand Sildenafil vs. Dextrose Candy on Maximum Exercise Capacity in Pulmonary Arterial Hypertension: A Randomized, Cross-Over Trial.

Sponsor

Silvia Ulrich

Enrollment

20 participants

Start Date

Sep 1, 2026

Study Type

INTERVENTIONAL

Conditions

Pulmonary Arterial Hypertension (PAH) (WHO Group 1 PH)

Summary

The goal of this clinical study is to investigate whether the additional intake of sildenafil 20mg on top of standard medical treatment results in a benefit on maximum exercise workload (Wmax) in patients with pulmonary arterial hypertension (PAH).

Eligibility

Min Age: 18 YearsMax Age: 80 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Dextrose and a drug called Sildenafil 20mg for people with pulmonary arterial hypertension (pah) (who group 1 ph). The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years to 80 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGDextrose

Administration of Dextrose Candy by mouth as a tablet.

DRUGSildenafil 20mg

Administration of Sildenafil 20mg by mouth as a tablet.

Locations(1)

University Hospital of Zurich, Department of Pulmonology

Zurich, Canton of Zurich, Switzerland

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NCT07824674

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