Phase 1 ACL Clinical Trials
4 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–4 of 4 trials
Recruiting
Phase 1Phase 2
A Phase I/II Study of Intraperitoneal Paclitaxel in Patients With Metastatic Appendiceal Adenocarcinoma
Metastatic Appendiceal AdenocarcinomaIntraperitoneal Paclitaxel
M.D. Anderson Cancer Center39 enrolled1 locationNCT06207305
Completed
Phase 1
Oral Paclitaxel for the Treatment of Cancer
Cancer requiring treatment with intravenous paclitaxel
Kinex Pharmaceuticals Inc40 enrolled6 locationsACTRN12615000894594
Completed
Phase 1
A randomised, double-blind, comparator study to assess the safety & tolerability of a single injection into the knee joint of MSB-CAR001 when combined with Hyaluronan compared to Hyaluronan alone in patients who have recently undergone an Anterior Cruciate Ligament Reconstruction.
Anterior Cruciate Ligament (ACL) reconstruction following an initial, unilateral acute ACL injury.Osteoarthritis post ACL repair
Mesoblast Ltd24 enrolled1 locationACTRN12609001018202
Recruiting
Phase 1
An evaluation of knee stability and functions following ACL reconstruction (semitendinosus/gracillis grafts) comparing manually versus mechanically tensioned grafts (using a tensioning device).
Knees requiring ACL-Anterior Cruciate Ligament reconstruction
Queensland Health50 enrolled1 locationACTRN12606000389505