Phase 1 Acute Leukaemia Clinical Trials

5 recruitingPhase 1

What is a Phase 1 trial?

Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.

Showing 15 of 5 trials

Recruiting
Phase 1Phase 2

The Safety and Tolerability of LBS-007 in Patients With Relapsed or Resistant Acute Leukaemias

Relapsed or Resistant Acute Leukaemias
Lin BioScience, Inc90 enrolled17 locationsNCT05756322
Not Yet Recruiting
Phase 1

Microbiome and Fibre Supplementation in Chimeric Antigen Receptor T cell Therapy - phase I clinical trial of safety and feasibility of oral fibre supplementation in CAR T

LymphomaMyelomaAcute Leukaemia
Metro North Hospital and Health Service30 enrolled1 locationACTRN12625000056493
Recruiting
Phase 1

Short-course treatment with venetoclax prior to non-myeloablative conditioning allogeneic stem cell transplantation for patients with haematological malignancies.

Acute leukaemia (myeloid and/or lymphoid, or biphenotypic)
Melbourne Health18 enrolled2 locationsACTRN12622000308796
Recruiting
Phase 1

Coadministration of Malignancy and Infection specific T cells after allogeneic stem cell Transplant for Acute Leukaemia with CD34+ selected stem cells

AspergillusInfluenza virusBK Virus+2 more
Western Sydney Local Health District, Westmead Hospital20 enrolled1 locationACTRN12618001090202
Terminated
Phase 1

Haploidentical stem cell transplantation with iCasp9 T cell addback in patients with poor risk haematological malignancies

Patients with high risk acute leukaemia, myelodysplastic syndrome or chronic myeloid leukaemia, who lack a suitable fully human leukocyte antigen (HLA)-matched or single-antigen mismatched donor.
Metro North Hospital and Health Service - Royal Brisbane and Womens’ Hospital12 enrolled1 locationACTRN12614000290695