Phase 1 Acute Myeloid Leukaemia (AML) Clinical Trials
5 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–5 of 5 trials
Recruiting
Phase 1Phase 2
A Multi-Site Break Through Cancer Trial: Targeting Measurable Residual Disease in Patients With Acute Myeloid Leukemia: A Phase 1/2 Study of Tagraxofusp, Azacitidine, and Venetoclax
LeukemiaBlood CancersBlood Cancer+1 more
Jacqueline Garcia, MD31 enrolled2 locationsNCT07148180
Recruiting
Phase 1
Effect of Moderate Renal Impairment and Race/Ethnicity on Treosulfan Pharmacokinetics
Myelodysplastic Syndrome (MDS)Allogeneic Hematopoietic Stem Cell Transplantation (HSCT)Acute Myeloid Leukaemia (AML)
medac GmbH36 enrolled4 locationsNCT05534620
Terminated
Phase 1
A clinical trial to assess the safety, distribution, effects on certain immune cells and anti-leukaemia effects of LAVA-1266 in patients with acute myeloid leukaemia or certain types of myelodysplastic syndrome
Refractory/Relapsed (R/R) acute myeloid leukaemia (AML)High risk myelodysplastic syndrome (MDS)Extremely high risk myelodysplastic syndrome (MDS)+1 more
LAVA Therapeutics N.V.50 enrolled4 locationsACTRN12624001214527
Recruiting
Phase 1
An Exploratory Randomized, Double-Blind, Placebo-Controlled, First-in-Human Study of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single and Multiple Ascending Doses of ZE63-0302 in Healthy Volunteers
Acute Myeloid Leukaemia (AML)
Eilean Therapeutics AU Pty Ltd (A subsidiary of Eilean Therapeutics LLC)88 enrolled1 locationACTRN12624000180516
Completed
Phase 1
Lenalidomide with epigenetic therapy in relapsed or refractory Acute Myeloid Leukaemia (AML)-Phase I
Relapsed or refractory Acute Myeloid Leukaemia (AML)
Australasian Leukaemia and Lymphoma Group18 enrolled3 locationsACTRN12612000303842