Phase 1 Advanced/Metastatic Solid Tumors Clinical Trials

12 recruitingPhase 1

What is a Phase 1 trial?

Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.

Showing 112 of 12 trials

Recruiting
Phase 1

A Study of ATG-022 in Patients With Advanced/Metastatic Solid Tumors

Advanced/Metastatic Solid Tumors
Antengene Biologics Limited156 enrolled22 locationsNCT05718895
Recruiting
Phase 1

A Study of DB-1317 in Selected Advanced/Metastatic Solid Tumors

Advanced/Metastatic Solid Tumors
DualityBio Inc.233 enrolled6 locationsNCT07141706
Recruiting
Phase 1

A Study to Learn About the Study Medicine Called PF-08046876 in People With Advanced Solid Tumors

Urothelial CarcinomaBladder CancerAdvanced/Metastatic Solid Tumors+1 more
Pfizer310 enrolled28 locationsNCT07090499
Recruiting
Phase 1Phase 2

Phase 1/II Clinical Study of SYS6043 in the Treatment of Advanced/Metastatic Solid Tumors

Advanced/Metastatic Solid Tumors
CSPC Megalith Biopharmaceutical Co.,Ltd.820 enrolled1 locationNCT07415863
Recruiting
Phase 1Phase 2

ADG126 in Combination With Pembrolizumab in Patients With Advanced/Metastatic Solid Tumors

Advanced/Metastatic Solid Tumors
Adagene Inc186 enrolled21 locationsNCT05405595
Recruiting
Phase 1

Study of ISM3412 in Participants With Locally Advanced/Metastatic Solid Tumors

Locally Advanced/Metastatic Solid Tumors
InSilico Medicine Hong Kong Limited80 enrolled9 locationsNCT06414460
Recruiting
Phase 1

Study of ESG406 in Adults With Solid Tumors

Locally Advanced/Metastatic Solid Tumors
Shanghai Escugen Biotechnology Co., Ltd556 enrolled3 locationsNCT06979674
Recruiting
Phase 1Phase 2

Study of MHB088C for Patients With Advanced Solid Malignant Tumors

Advanced/Metastatic Solid Tumors
Qilu Pharmaceutical Co., Ltd.515 enrolled1 locationNCT07102004
Recruiting
Phase 1Phase 2

A Phase I/II of HRS-6719 in Patients With Advanced/Metastatic Solid Tumors

Advanced/Metastatic Solid Tumors
Shandong Suncadia Medicine Co., Ltd.120 enrolled1 locationNCT06922357
Recruiting
Phase 1

First in Human Study of EMB-07 in Locally Advanced/Metastatic Solid Tumors or Relapse/Refractory Lymphoma

Advanced/Metastatic Solid TumorsRelapse/Refractory Lymphoma
EpimAb Biotherapeutics (Suzhou)Co., Ltd.150 enrolled10 locationsNCT05607498
Recruiting
Phase 1Phase 2

A Study of Bispecific Antibody MCLA-158 in Patients With Advanced Solid Tumors

Advanced/Metastatic Solid Tumors
Merus B.V.523 enrolled45 locationsNCT03526835
Recruiting
Phase 1Phase 2

PE0116 and PE0105 Injection in Treatment of Patients With Advanced Solid Tumor

Locally Advanced/Metastatic Solid Tumors
Shanghai HyaMab Biotech Co.,Ltd.120 enrolled1 locationNCT05801237