Advanced Rectal Carcinoma Clinical Trials

1 recruiting

Frequently Asked Questions

Common questions about Advanced Rectal Carcinoma clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 18 of 8 trials

Recruiting
Phase 2

Serplulimab Combined With CAPEOX + Celecoxib as Neoadjuvant Treatment for Locally Advanced Rectal Cancer

Locally Advanced Rectal CarcinomapMMRMSS+1 more
Zhejiang University50 enrolled1 locationNCT05731726
Recruiting
Phase 3

Modulated Electro-Hyperthermia in Combination With Multimodal Therapy for Locally Advanced Rectal Cancer

Locally Advanced Rectal Carcinoma
Shih-Kai Hung126 enrolled1 locationNCT07372300
Recruiting
Early Phase 1

An Investigational Scan (64Cu-Labeled M5A Antibody) in Combination With SOC Chemotherapy and Radiotherapy in Locally Advanced Rectal Cancer

Locally Advanced Rectal CarcinomaStage III Rectal Cancer AJCC v8Stage IIIA Rectal Cancer AJCC v8+2 more
City of Hope Medical Center15 enrolled1 locationNCT05245786
Recruiting
Phase 1

Short Course Radiation Therapy and Combination Chemotherapy for the Treatment of Stage II-III Rectal Cancer

Rectal AdenocarcinomaLocally Advanced Rectal CarcinomaStage II Rectal Cancer AJCC v8+7 more
Jonsson Comprehensive Cancer Center25 enrolled1 locationNCT04703101
Recruiting
Phase 2

Time-Restricted Eating Versus Nutritional Counseling for the Reduction of Radiation or Chemoradiation Tx Side Effects in Patients With Prostate, Cervical, or Rectal Cancers

Malignant Solid NeoplasmLocally Advanced Cervical CarcinomaRecurrent Prostate Carcinoma+15 more
City of Hope Medical Center60 enrolled1 locationNCT05722288
Recruiting
Phase 2

Prophylactic Mesalamine to Prevent Colitis Following Treatment With Ipilimumab/Nivolumab (Ipi/Nivo)

Advanced MelanomaDiarrheaImmune-related Adverse Event+1 more
AHS Cancer Control Alberta20 enrolled1 locationNCT05663775
Recruiting
Phase 2

Circulating Tumor DNA-guided Neoadjuvant Treatment Strategy for Locally Advanced Rectal Cancer

Circulating Tumor DNALocally Advanced Rectal Carcinoma
Peking Union Medical College Hospital470 enrolled1 locationNCT05601505
Recruiting
Not Applicable

Organ Preservation in Rectal Cancer: Contact X-ray Brachytherapy vs Extending the Waiting Interval and Local Excision

Quality of LifeRectal CancerLocally Advanced Rectal Carcinoma+1 more
The Netherlands Cancer Institute168 enrolled7 locationsNCT05772923