Diarrhea Clinical Trials

14 recruiting

Diarrhea Trials at a Glance

39 actively recruiting trials for diarrhea are listed on ClinicalTrialsFinder across 6 cities in 38 countries. The largest study group is Not Applicable with 13 trials, with the heaviest enrollment activity in Rochester, Roma, and Madrid. Lead sponsors running diarrhea studies include Johns Hopkins Bloomberg School of Public Health, Lumen Bioscience, Inc., and Mayo Clinic.

Browse diarrhea trials by phase

Treatments under study

About Diarrhea Clinical Trials

Looking for clinical trials for Diarrhea? There are currently 14 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Diarrhea trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Diarrhea clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 39 trials

Recruiting
Phase 3

Carcinoid Syndrome Efficacy Study Featuring an Oral Daily Paltusotine Regimen

Carcinoid TumorCarcinoid Tumor of PancreasCarcinoid Tumor of Liver+6 more
Crinetics Pharmaceuticals Inc.141 enrolled51 locationsNCT07087054
Recruiting
Phase 3

VE303 for Prevention of Recurrent Clostridioides Difficile Infection

Clostridium Difficile Infection RecurrenceClostridium DifficileClostridioides Difficile Infection+7 more
Vedanta Biosciences, Inc.852 enrolled215 locationsNCT06237452
Recruiting
Not Applicable

Testing a Scalable Model of the Cholera Hospital-Based Intervention for 7 Days (CHoBI7)

Diarrhea InfectiousCholera
Johns Hopkins Bloomberg School of Public Health1,600 enrolled1 locationNCT06498817
Recruiting
Phase 1

KAN-004 for Immune-Related Diarrhea or Colitis

ColitisDiarrhea Caused by Antitumor Drugs
Centre hospitalier de l'Université de Montréal (CHUM)21 enrolled1 locationNCT07196410
Recruiting
Not Applicable

Gelsectan® in the Treatment of Patients With Diarrhoea-predominant Irritable Bowel Syndrome

Irritable Bowel Syndrome (IBS)Irritable Bowel Syndrome of Diarrhea Type (IBS-D)
Devintec Sagl330 enrolled12 locationsNCT06681012
Recruiting

Observational Study of Gut Microbiota in Abemaciclib-Treated Patients With and Without Diarrhea

Breast NeoplasmsAbemaciclibHormone Receptor-Positive Breast Cancer+4 more
Hubei Cancer Hospital60 enrolled1 locationNCT07264998
Recruiting
Phase 2

The Impact of Shigellosis and Recommended Treatment in Children

ShigellaDiarrhea InfectiousGrowth & Development
Johns Hopkins Bloomberg School of Public Health700 enrolled4 locationsNCT07433426
Recruiting
Phase 4

Rifaximin 200 mg Plus Oral Rehydration vs Oral Rehydration Alone in Children With Acute Diarrhea

Diarrhea
Bausch Health Americas, Inc.54 enrolled5 locationsNCT07285785
Recruiting
Phase 1

Fecal Microbiota Transplantation in Treating Immune-Checkpoint Inhibitor Induced-Diarrhea or Colitis in Genitourinary Cancer Patients

Breast CancerOvarian CancerCervical Cancer+6 more
M.D. Anderson Cancer Center40 enrolled1 locationNCT04038619
Recruiting

Development of New Diagnostic Tools in Capsule Endoscopy

TumorCeliac DiseaseCrohn Disease+2 more
Assistance Publique - Hôpitaux de Paris10,000 enrolled1 locationNCT06152289
Recruiting
Not Applicable

Probiotic in Patients With Bile Acid Malabsorption/Diarrhea

Bile Acid MalabsorptionBile Acid Diarrhea
Mayo Clinic24 enrolled1 locationNCT06609148
Recruiting

Defining Ileorectal Syndrome: a Prospective Observational Study

DiarrheaUrgency IncontinenceTotal Colectomy+1 more
Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital30 enrolled1 locationNCT07385196
Recruiting

Magnesium in Gastrointestinal Disease

Ileostomy - StomaBile Acid MalabsorptionColitis Ulcerative+9 more
University of Aarhus120 enrolled1 locationNCT07338565
Recruiting
Early Phase 1

Novel Pilot Study to Treat Symptoms of IBS With Diarrhea Using Combination Therapy of a Low-FODMAP Diet and a Neuromodulator

DiarrheaIBS - Irritable Bowel Syndrome
Mayo Clinic20 enrolled1 locationNCT06684470
Recruiting
Not Applicable

Preventative Intervention for Cholera for 7 Days

Diarrhea InfectiousCholeraWater-Related Diseases
Johns Hopkins Bloomberg School of Public Health2,900 enrolled2 locationsNCT05166850
Recruiting
Phase 1

A Study of SER-155 to Treat Diarrhea in People on Immunotherapy

DiarrheaEnterocolitis
Memorial Sloan Kettering Cancer Center15 enrolled7 locationsNCT06801067
Recruiting
Not Applicable

Cholera-Hospital-Based-Intervention-for-7-Days (CHoBI7) Water, Sanitation, and Hygiene (WASH) Case Area Targeted Intervention (CATI)

DiarrheaCholera
Johns Hopkins Bloomberg School of Public Health3,140 enrolled2 locationsNCT06003816
Recruiting
Phase 4

Treatment of Bile Acid Diarrhoea With Atorvastatin

Bile Acid MalabsorptionBile Acid Diarrhea
Asger Lund, MD20 enrolled1 locationNCT07042165
Recruiting
Phase 1

First in Human Dose Escalation Study Evaluating the Safety and Immunogenicity of IVT's Shigella-04 Vaccine in Healthy Young Adults

DiarrheaShigella
Inventprise Inc.60 enrolled1 locationNCT07205926
Recruiting
Not Applicable

FMT in Checkpoint Inhibitor-mediated Diarrhea and Colitis

ColitisDiarrheaKidney Cancer+1 more
University of Aarhus20 enrolled1 locationNCT06206707