Diarrhea Clinical Trials

53 recruitingLast updated: June 17, 2026

There are 53 actively recruiting diarrhea clinical trials across 41 countries. Studies span Not Applicable, Phase 2, Phase 1, Phase 3, Early Phase 1, Phase 4. Top locations include Barcelona, Spain, Madrid, Spain, Roma, Italy. Updated daily from ClinicalTrials.gov.


Diarrhea Trials at a Glance

53 actively recruiting trials for diarrhea are listed on ClinicalTrialsFinder across 6 cities in 41 countries. The largest study group is Not Applicable with 19 trials, with the heaviest enrollment activity in Barcelona, Madrid, and Roma. Lead sponsors running diarrhea studies include Johns Hopkins Bloomberg School of Public Health, Children's Hospital of Fudan University, and Lumen Bioscience, Inc..

Browse diarrhea trials by phase

Treatments under study

About Diarrhea Clinical Trials

Looking for clinical trials for Diarrhea? There are currently 16 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Diarrhea trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Diarrhea clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 53 trials

Recruiting
Not Applicable

Inactivated Bacteroides Fragilis for Prevention of Chemotherapy-Induced Diarrhea

Chemotherapy-induced Diarrhea
Shenzhen Hospital of Southern Medical University200 enrolled1 locationNCT07309315
Recruiting
Phase 3

VE303 for Prevention of Recurrent Clostridioides Difficile Infection

Clostridium Difficile Infection RecurrenceClostridium DifficileClostridioides Difficile Infection+7 more
Vedanta Biosciences, Inc.852 enrolled215 locationsNCT06237452
Recruiting
Not Applicable

Evaluation of the Efficacy and Safety of Gelsectan in the Treatment of Diarrhea-predominant Irritable Bowel Syndrome

Diarrhea-predominant irritable bowel syndromeIrritable Bowel Syndrome of Diarrhea Type (IBS-D)
University Medical Center Ho Chi Minh City (UMC)90 enrolled1 locationNCT07000383
Recruiting

Balanced Crystalloid vs Normal Saline in Pediatric Acute Gastroenteritis

DiarrheaDehydrationVomiting+2 more
Aydin Adnan Menderes University180 enrolled1 locationNCT07610382
Recruiting
Phase 2

Probiotics for Abemaciclib-Induced Abdominal Discomfort.

Breast CancerChemotherapy-induced Diarrhea
Leeuwenhoek Laboratories Co. Ltd.80 enrolled1 locationNCT07605728
Recruiting
Phase 2

A Study of Brenipatide (LY3537031) in Participants With Irritable Bowel Syndrome-Diarrhea (IBS-D)

DiarrheaIrritable Bowel Syndrome
Eli Lilly and Company531 enrolled88 locationsNCT07545759
Recruiting
Not Applicable

Probiotic in Patients With Bile Acid Malabsorption/Diarrhea

Bile Acid MalabsorptionBile Acid Diarrhea
Mayo Clinic24 enrolled1 locationNCT06609148
Recruiting
Not Applicable

The Impact of Pre-emptive Home Delivery of ORS + Zinc on Treatment for Child Diarrhea

Diarrhea Toddler
RAND103,920 enrolled1 locationNCT06444633
Recruiting
Not Applicable

Randomized, Blinded, Placebo-Controlled Evaluation of BioAmicus Complete

ConstipationAtopic DermatitisInfantile Colics+1 more
NovoNatum Ltd140 enrolled1 locationNCT07444008
Recruiting
Phase 2

Fecal Microbiota Transplantation for IBS

DiarrheaIrritable Bowel Syndrome
Madhusudan (Madhu) Grover, MBBS43 enrolled1 locationNCT05776914
Recruiting
Not Applicable

Repeated Transcranial Magnetic Stimulation for the Treatment of Diarrhea-Predominant Irritable Bowel Syndrome: A Randomized Clinical Trial

Intestinal FloraIrritable Bowel SyndromeChronic Diarrhea+2 more
The First Affiliated Hospital of Soochow University46 enrolled1 locationNCT07581756
Recruiting
Phase 3

Carcinoid Syndrome Efficacy Study Featuring an Oral Daily Paltusotine Regimen

Carcinoid TumorCarcinoid Tumor of PancreasCarcinoid Tumor of Liver+6 more
Crinetics Pharmaceuticals Inc.141 enrolled51 locationsNCT07087054
Recruiting
Phase 2

Efficacy of Rifaximin With NAC in IBS-D

IBS - Irritable Bowel SyndromeIBS-D (Diarrhea-predominant)
Mark Pimentel, MD225 enrolled1 locationNCT06727422
Recruiting
Not Applicable

Testing a Scalable Model of the Cholera Hospital-Based Intervention for 7 Days (CHoBI7)

Diarrhea InfectiousCholera
Johns Hopkins Bloomberg School of Public Health1,600 enrolled1 locationNCT06498817
Recruiting
Phase 1

KAN-004 for Immune-Related Diarrhea or Colitis

ColitisDiarrhea Caused by Antitumor Drugs
Centre hospitalier de l'Université de Montréal (CHUM)21 enrolled1 locationNCT07196410
Recruiting
Not Applicable

Gelsectan® in the Treatment of Patients With Diarrhoea-predominant Irritable Bowel Syndrome

Irritable Bowel Syndrome (IBS)Irritable Bowel Syndrome of Diarrhea Type (IBS-D)
Devintec Sagl330 enrolled12 locationsNCT06681012
Recruiting

Observational Study of Gut Microbiota in Abemaciclib-Treated Patients With and Without Diarrhea

Breast NeoplasmsAbemaciclibHormone Receptor-Positive Breast Cancer+4 more
Hubei Cancer Hospital60 enrolled1 locationNCT07264998
Recruiting
Phase 2

The Impact of Shigellosis and Recommended Treatment in Children

ShigellaDiarrhea InfectiousGrowth & Development
Johns Hopkins Bloomberg School of Public Health700 enrolled4 locationsNCT07433426
Recruiting
Not Applicable

Whole Genome Sequencing Versus Whole Exome Sequencing for Congenital Diarrhea and Enteropahty

Diarrhea InfantileEnteropathy
Children's Hospital of Fudan University180 enrolled1 locationNCT04528303
Recruiting
Phase 1

Fecal Microbiota Transplantation in Treating Immune-Checkpoint Inhibitor Induced-Diarrhea or Colitis in Genitourinary Cancer Patients

Breast CancerOvarian CancerCervical Cancer+6 more
M.D. Anderson Cancer Center40 enrolled1 locationNCT04038619