Phase 1 AL Amyloidosis Clinical Trials
6 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–6 of 6 trials
Recruiting
Phase 1
Study of GC012F, CAR-T Therapy Targeting CD19 and BCMA in Chinese Participants With Relapsed or Refractory AL Amyloidosis
Relapsed/Refractory AL Amyloidosis
Gracell Biotechnologies (Shanghai) Co., Ltd.9 enrolled9 locationsNCT07250269
Recruiting
Phase 1
Venetoclax, MLN9708 (Ixazomib Citrate) and Dexamethasone for the Treatment of Relapsed or Refractory Light Chain Amyloidosis
Refractory AL AmyloidosisRecurrent AL Amyloidosis
National Cancer Institute (NCI)24 enrolled16 locationsNCT04847453
Recruiting
Phase 1Phase 2
A Phase 1b/2 Study of CAR T Cell Therapy Targeting CD19 and BCMA in Participants With Relapsed or Refractory AL Amyloidosis.
AmyloidosisLight Chain AmyloidosisRelapsed AL Amyloidosis+1 more
Alexion Pharmaceuticals, Inc.91 enrolled18 locationsNCT07081646
Recruiting
Phase 1Phase 2
Elranatamab in Patients With Relapsed or Refractory AL Amyloidosis
AL Amyloidosis
Brigham and Women's Hospital49 enrolled1 locationNCT06569147
Recruiting
Phase 1Phase 2
Phase 1/2a Study of Belantamab Mafodotin in Relapsed or Refractory AL Amyloidosis
AmyloidosisAL Amyloidosis
University of Texas Southwestern Medical Center37 enrolled3 locationsNCT05145816
Recruiting
Phase 1Phase 2
Venetoclax-Dexamethasone in Relapsed and/or Refractory t(11;14) Amyloidosis
AL Amyloidosis
Rajshekhar Chakraborty, MD53 enrolled4 locationsNCT05451771