Phase 2 ALS Clinical Trials
24 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 24 trials
Recruiting
Phase 2
A Clinical Trial of Early Ventilation in Amyotrophic Lateral Sclerosis (EVENT ALS)
Chronic respiratory failureNon-invasive ventilationRespiratory Insufficiency+7 more
University of Pennsylvania48 enrolled3 locationsNCT07071935
Recruiting
Phase 2
Tofersen in Non-SOD1 ALS
ALS (Amyotrophic Lateral Sclerosis)
Washington University School of Medicine30 enrolled2 locationsNCT07294144
Recruiting
Phase 2
PHENOGENE-1A (Cromolyn) Treatment in Patients With Mild to Moderate ALS
Amyotrophic Lateral Sclerosis(ALS)
PhenoNet, Inc.105 enrolled20 locationsNCT07142291
Recruiting
Phase 2
Smart AFO and 5-Azacitidine to Enhance Mobility in Children With Cerebral Palsy
Cerebral Palsy
Shirley Ryan AbilityLab60 enrolled1 locationNCT07434492
Recruiting
Phase 2
tSCS and 5-Azacitidine for Enhanced Motor Outcomes in Cerebral Palsy
Cerebral Palsy
Shirley Ryan AbilityLab80 enrolled1 locationNCT07433023
Recruiting
Phase 1Phase 2
A Clinical Trial to Evaluate NB-4746 in Participants With Amyotrophic Lateral Sclerosis.
Amyotrophic Lateral Sclerosis(ALS)
Nura Bio80 enrolled6 locationsNCT07369076
Recruiting
Phase 2
Study of COYA 302 for the Treatment of ALS
Amyotrophic Lateral Sclerosis(ALS)
Coya Therapeutics120 enrolled25 locationsNCT07161999
Recruiting
Phase 2
Psilocybin Therapy for Psychological Distress in Palliative Patients
COPD, Chronic Obstructive Pulmonary DiseaseMajor Depressive Disorder (MDD)ALS (Amyotrophic Lateral Sclerosis)+2 more
University Medical Center Groningen108 enrolled4 locationsNCT06782724
Recruiting
Phase 1Phase 2
Examining a Novel Gastrointestinal Intervention to Negate Environmental Toxicants (ENGINE)
Toxicant ExposureFirefighterOccupational Exposure to Chemicals
University of California, San Francisco50 enrolled1 locationNCT07226440
Recruiting
Phase 1Phase 2
Intestinal Microbiome Transplant in ALS
Amyotrophic Lateral Sclerosis(ALS)
Duke University20 enrolled1 locationNCT07017946
Recruiting
Phase 1Phase 2
First in Human (FIH) Study of ALN-SOD in Adult Participants With Amyotrophic Lateral Sclerosis Associated With Mutation in the SOD1 Gene (SOD1-ALS)
Amyotrophic Lateral Sclerosis(ALS)Mutation in the Superoxide Dismutase-1 (SOD1) Gene
Regeneron Pharmaceuticals42 enrolled16 locationsNCT06351592
Recruiting
Phase 2
Mitochondrial Capacity Boost in ALS (MICABO-ALS) Trial
Amyotrophic Lateral Sclerosis(ALS)
Dallas VA Medical Center60 enrolled1 locationNCT04244630
Recruiting
Phase 1Phase 2
Efficacy of Prednisolone Versus Cerebrolysin in the Treatment of Bell's Palsy
Bell Palsy
October 6 University90 enrolled1 locationNCT05821075
Recruiting
Phase 2Phase 3
Therapeutic Photobiomodulation and Tretament of Spasticity
Muscle SpasticityCerebral PalsyPhotobiomodulation+1 more
University of Nove de Julho28 enrolled2 locationsNCT06536751
Recruiting
Phase 1Phase 2
Safety, PK and Biodistribution of 18F-OP-801 in Patients With ALS, AD, MS, PD and Healthy Volunteers
Amyotrophic Lateral Sclerosis(ALS)Alzheimer Disease (AD)Parkinson Disease (PD)+1 more
Ashvattha Therapeutics, Inc.65 enrolled3 locationsNCT05395624
Recruiting
Phase 2Phase 3
Wereables for Upper Limb Functionality in Hemiparesis
Unilateral Cerebral Palsy
Universidade da Coruña40 enrolled1 locationNCT06872736
Recruiting
Phase 2
The NADAPT Study: a Randomized Double-blind Trial of NAD Replenishment Therapy for Atypical Parkinsonism
Multiple System AtrophyCorticobasal SyndromeProgressive Supranuclear Palsy
Haukeland University Hospital330 enrolled3 locationsNCT06162013
Terminated
Phase 2
An investigation into the role of oxytocin in emotion after injury or trauma
Individuals who have experienced a traumatic injury.
Monash University25 enrolled1 locationACTRN12617001208392
Completed
Phase 2
Functional electrical stimulation in children with unilateral spastic cerebral palsy: A study of the effects based on the international classification of functioning framework.
Unilateral Spastic Cerebral Palsy
University of Western Australia30 enrolled1 locationACTRN12614000949684
Completed
Phase 2Phase 3
21 day trial into the weight reduction effects of supplementation with 1g and 500mg SolaThin.
weight and appetite in overweight and obese individuals
CYVEX NUTRITION, INC60 enrolled1 locationACTRN12612000198820