Phase 2 ALT Clinical Trials

134 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 120 of 134 trials

Recruiting
Phase 2

Effects of Sucralose on Drug Absorption and Metabolism (The SweetMeds Study)

Healthy VolunteersOverweight
National Institute on Alcohol Abuse and Alcoholism (NIAAA)150 enrolled1 locationNCT03407079
Recruiting
Phase 2

Early Metabolic Effects of Antiretroviral Drugs in Healthy volUnteers: a Phase 2 Randomized Study

Weight GainHealthy VolunteerMetabolic Effects+1 more
National Institute of Allergy and Infectious Diseases (NIAID)120 enrolled1 locationNCT05652478
Recruiting
Phase 2

Neurobiology of Suicide

DepressionHealthy Volunteers
National Institute of Mental Health (NIMH)325 enrolled1 locationNCT02543983
Recruiting
Phase 1Phase 2

Behavioral Economic Attributes of Recreation

Cardiometabolic Health Indicators
Rush University Medical Center120 enrolled1 locationNCT07282418
Recruiting
Phase 2

Efficacy and Safety of TYRA-300 in Participants With FGFR3 Altered Low Grade, Intermediate Risk Non-Muscle Invasive Bladder Cancer

Low-grade NMIBCFGFR Gene AmplificationFGFR Gene Alterations+3 more
Tyra Biosciences, Inc90 enrolled42 locationsNCT06995677
Recruiting
Phase 1Phase 2

Suvorexant for Alcohol Use Disorder (AUD): Neural Mechanisms

Healthy VolunteersAlcohol Use Disorder (AUD)
National Institute on Alcohol Abuse and Alcoholism (NIAAA)180 enrolled1 locationNCT06484075
Recruiting
Phase 1Phase 2

A Phase 1/2 Study of PRO-203 in Healthy Volunteers and Participants With Systemic Sclerosis.

Healthy VolunteersSclerodermaSystemic Sclerosis (SSc)+1 more
Prolium Bioscience, Inc44 enrolled3 locationsNCT07641634
Recruiting
Phase 2

Vaginal Detection of Orally Delivered Probiotic Strains in Healthy Women

Focus is on Healthy Subjects
Lallemand Health Solutions72 enrolled1 locationNCT07246161
Recruiting
Phase 1Phase 2

A Study to Evaluate BMS-986470 in Healthy Volunteers and Participants With Sickle Cell Disease

Healthy VolunteersAnemia, Sickle Cell
Bristol-Myers Squibb184 enrolled34 locationsNCT06481306
Recruiting
Phase 2

Improving Vaccine Protection for Adults

Healthy AdultImmune System Responses and Trained Immunity After AS01 Administration
Singapore General Hospital40 enrolled1 locationNCT07527247
Recruiting
Phase 1Phase 2

A Study to Evaluate ALN-4324 in Overweight to Obese Healthy Volunteers and in Overweight to Obese Patients With T2DM

Type 2 Diabetes Mellitus (T2DM)Obese or Overweight Healthy Volunteers
Alnylam Pharmaceuticals144 enrolled22 locationsNCT06845202
Recruiting
Phase 2

A Study to Assess the Efficacy and Safety of FORE8394 in Participants With Cancer Harboring BRAF Alterations

Solid TumorsHGGCancer Harboring BRAF Alterations+1 more
Fore Biotherapeutics254 enrolled70 locationsNCT05503797
Recruiting
Phase 2

Investigating the Interaction of Psilocybin and Context of Its Administration in Healthy Volunteers

Healthy Participants With Lower-than-average Mental Well-being
Robin Carhart-Harris, PhD, MA120 enrolled1 locationNCT06626139
Recruiting
Phase 1Phase 2

Novel Biomarkers of Non-IgE Immediate Hypersensitivity Drug Reactions

Healthy VolunteerVancomycinHypersensitivity Reactions
Johns Hopkins University25 enrolled1 locationNCT07605806
Recruiting
Phase 1Phase 2

Study of ABS-201 Evaluating Single and Multiple Ascending Doses in Healthy Adults With and Without Androgenetic Alopecia

Androgenetic alopecia (AGA)Healthy Volunteers - Male and Female
Absci Pty Ltd.227 enrolled4 locationsNCT07317544
Recruiting
Phase 1Phase 2

Study of TGM-312-SC01 in Healthy Participants and Adults With MASH

Healthy ParticipantsMASH - Metabolic Dysfunction-Associated Steatohepatitis
Tangram Therapeutics Plc99 enrolled1 locationNCT07427680
Recruiting
Phase 2Phase 3

Virtual Menstrual Pain Approaches in Females

Digital HealthAcupressureMetabolomics+5 more
Nanyang Technological University145 enrolled1 locationNCT07497711
Recruiting
Phase 1Phase 2

Pilot Trial of Fisetin in Healthy Volunteers and Older Patients With Multimorbidity

HealthyMultimorbidity
Ove Andersen60 enrolled1 locationNCT06431932
Not Yet Recruiting
Phase 2

Assessing the effect of ketamine on disruption of memory reconsolidation in Post Traumatic Stress Disorder

Mental Health
University of the Sunshine Coast44 enrolled1 locationACTRN12626000603314
Recruiting
Phase 1Phase 2

A Study to Investigate IGT-303 in Healthy Volunteers and Participants With Chronic Kidney Disease

Healthy VolunteersChronic Kidney Disease
Ingenia Therapeutics INC94 enrolled5 locationsNCT07231679