RecruitingPhase 2Phase 3NCT07497711

Virtual Menstrual Pain Approaches in Females

Virtual Auricular Acupressure and Baduanjin Qigong Exercise for Preventing Menstrual Pain in Females: A Randomized Clinical Trial


Sponsor

Nanyang Technological University

Enrollment

145 participants

Start Date

Apr 15, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

This research study is testing two self-care approaches that may help prevent or reduce period pain in young females with primary dysmenorrhea, a common condition that causes painful menstrual cramps. Participants will be placed by chance into 1 of 3 groups: auricular acupressure, Baduanjin qigong, or a self-care education comparison group. The auricular acupressure and Baduanjin groups will receive online training and then practice the treatment on their own for 12 weeks. The main question is whether these two approaches can reduce the severity of menstrual pain. The study will also look at whether they can improve other symptoms that often happen with period pain, such as tiredness, poor sleep, anxiety, low mood, trouble concentrating, and reduced physical function. Researchers will also study stool and blood-related biological markers to better understand whether changes in gut bacteria and body metabolism may be linked to symptom improvement. A total of 145 participants will take part in the study at NTU, and any side effects or other safety concerns will be checked every week.


Eligibility

Sex: FEMALEMin Age: 16 YearsMax Age: 35 Years

Inclusion Criteria8

  • - 35 years of age
  • Regular menstrual cycles (28 days ± 7 days) in 3 months prior to enrollment
  • Primary dysmenorrhea confirmed by a study clinician or the participant's primary care doctor
  • Two or more episodes of menstrual cramps in the past 2 months, scored at least 4 points on the worst pain item of the Brief Pain Inventory (BPI)
  • Stated willingness to comply with all study procedures and availability for the duration of the study
  • Ability to download, install, and navigate the study-specific digital content and use its core functions for training, self-guided intervention administration, and data entry
  • Ability to understand the nature of the study and willingness to give informed consent.
  • Note: Patients are required to submit a medical certificate from their primary care physician documenting a clinical diagnosis of primary dysmenorrhea.

Exclusion Criteria5

  • Uncontrolled neurological diseases, immunodeficiency, bleeding disorders, and allergies
  • The presence of another Axis I disorder not in remission
  • Lactating or pregnant, or those planning to become pregnant in the coming half year
  • Undergoing other trials for pain management during the study period
  • Plan to initiate other pain therapies for menstrual pain management in the proceeding 3 months

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Interventions

BEHAVIORALVirtual Auricular Acupressure

Virtual auricular acupressure involved acupuncturist-led virtual auricular acupressure treatment and self-administered application in this trial.

BEHAVIORALVirtual Baduanjin Qigong Exercise

Virtual Baduanjin Qigong Exercise involves instructor-led virtual exercise training and self-administered Baduanjin Qigong Exercise in this study.

BEHAVIORALSelf Education

Attention Control with virtual training on menstrual hygiene and self-led menstrual health education.


Locations(1)

iHealth Lab, Nanyang Technological University

Singapore, Singapore

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NCT07497711


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