Phase 1 AMD Clinical Trials

7 recruitingPhase 1

What is a Phase 1 trial?

Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.

Showing 17 of 7 trials

Recruiting
Phase 1

A Phase 1 Study of ABF-101 in Single- and Multiple-Ascending Doses

AMD - Age-Related Macular DegenerationAge-related Macular Degeneration (ARMD)
Aptabio Therapeutics, Inc.68 enrolled1 locationNCT07330674
Recruiting
Phase 1Phase 2

A Phase 1/2 Study to Evaluate the Safety and Efficacy of Intravitreal Administration of BS01 in Patients With Geographic Atrophy Secondary to Dry AMD

Geographic Atrophy (GA) Secondary to Dry Age-related Macular Degeneration (AMD)
Bionic Sight LLC40 enrolled1 locationNCT07158775
Recruiting
Phase 1Phase 2

Study of AR-14034 in Participants With Neovascular Age-Related Macular Degeneration (nAMD)

Neovascular Age-Related Macular Degeneration (nAMD)
Alcon Research140 enrolled42 locationsNCT05769153
Recruiting
Phase 1Phase 2

Study of VOY-101 in Patients With Advanced Non-Neovascular Age-Related Macular Degeneration

Geographic AtrophyAge-Related Macular DegenerationNon-neovascular AMD
Perceive Biotherapeutics, Inc.60 enrolled11 locationsNCT06087458
Recruiting
Phase 1Phase 2

Safety and Efficacy of Oral HX9428 Tablets in Subjects With Wet Age-related Macular Degeneration (wAMD)

wet age related macular degeneration (AMD)
Fujian Haixi Pharmaceuticals Co., Ltd.198 enrolled1 locationNCT07185841
Recruiting
Phase 1Phase 2

Multicenter, Phase I/II Study to Evaluate the Safety, Tolerability, PK and Efficacy of SCT520FF in Patients With nAMD

nAMD
Sinocelltech Ltd.82 enrolled1 locationNCT06672536
Completed
Phase 1

A Phase 1b, Open-Label, Parallel Single-Dose Study to Evaluate the Pharmacokinetics and Pharmacodynamics of Tinlarebant in Healthy Volunteers Aged 50-85

Dry Age related macular degeneration (AMD)
RBP4 Pty Ltd16 enrolled1 locationACTRN12622001520729