Phase 2 AMD Clinical Trials

13 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 113 of 13 trials

Recruiting
Phase 2Phase 3

Pivotal 1 Study of ABBV-RGX-314 (Also Known as RGX-314) Gene Therapy Administered Via Subretinal Delivery One Time in Participants With nAMD

AMDnAMD
AbbVie630 enrolled89 locationsNCT04704921
Recruiting
Phase 2

Long-Term Analysis of DImethyl Fumarate, to Slow the Growth of Areas of Geographic Atrophy

Age related macular degeneration (AMD)
Assistance Publique - Hôpitaux de Paris90 enrolled1 locationNCT04292080
Recruiting
Phase 1Phase 2

A Phase 1/2 Study to Evaluate the Safety and Efficacy of Intravitreal Administration of BS01 in Patients With Geographic Atrophy Secondary to Dry AMD

Geographic Atrophy (GA) Secondary to Dry Age-related Macular Degeneration (AMD)
Bionic Sight LLC40 enrolled1 locationNCT07158775
Recruiting
Phase 1Phase 2

Study of AR-14034 in Participants With Neovascular Age-Related Macular Degeneration (nAMD)

Neovascular Age-Related Macular Degeneration (nAMD)
Alcon Research140 enrolled42 locationsNCT05769153
Recruiting
Phase 2

Study to Evaluate Efficacy and Safety of ONL1204 in Patients With GA Associated With AMD

Age related macular degeneration (AMD)Geographic Atrophy (GA)
ONL Therapeutics324 enrolled28 locationsNCT06659445
Recruiting
Phase 2

A Dose-masked Study of Intravitreal EYE103 in Participants With NVAMD or Macular Edema Following BRVO

Neovascular Age-Related Macular Degeneration (NVAMD)Branch Retinal Vein Occlusion (BRVO)
EyeBiotech Ltd.160 enrolled49 locationsNCT07205887
Recruiting
Phase 1Phase 2

Study of VOY-101 in Patients With Advanced Non-Neovascular Age-Related Macular Degeneration

Geographic AtrophyAge-Related Macular DegenerationNon-neovascular AMD
Perceive Biotherapeutics, Inc.60 enrolled11 locationsNCT06087458
Recruiting
Phase 1Phase 2

Safety and Efficacy of Oral HX9428 Tablets in Subjects With Wet Age-related Macular Degeneration (wAMD)

wet age related macular degeneration (AMD)
Fujian Haixi Pharmaceuticals Co., Ltd.198 enrolled1 locationNCT07185841
Recruiting
Phase 1Phase 2

Multicenter, Phase I/II Study to Evaluate the Safety, Tolerability, PK and Efficacy of SCT520FF in Patients With nAMD

nAMD
Sinocelltech Ltd.82 enrolled1 locationNCT06672536
Recruiting
Phase 2

Trial to Evaluate the Safety and Efficacy of EB-203 in Patients With Neovascular Age-related Macular Degeneration

Neovascular Age-Related Macular Degeneration (nAMD)
EyebioKorea, Inc.50 enrolled5 locationsNCT06487039
Not Yet Recruiting
Phase 2

A Phase II, Multicentre, 2-part, Study of the Safety, Tolerability, and Efficacy of Intravitreal Fludrocortisone Acetate in Subjects with Geographic Atrophy Secondary to Age-related Macular Degeneration - Part B

Geographic atrophy (GA) secondary to age-related macular degeneration (AMD)
EyeCo Pty Ltd126 enrolled1 locationACTRN12624000997550
Active
Phase 2

A Phase II, Multicentre, 2-part, Study of the Safety, Tolerability, and Efficacy of Intravitreal Fludrocortisone Acetate in Subjects with Geographic Atrophy Secondary to Age-related Macular Degeneration

Geographic atrophy (GA) secondary to age-related macular degeneration (AMD)
EyeCo Pty Ltd9 enrolled1 locationACTRN12624000971538
Completed
Phase 2

Safety study of PF582 versus Lucentis in patients with age related macular degeneration

Age related macular degeneration (AMD)
Pfenex Inc.25 enrolled1 locationACTRN12613001303730