Amputee Clinical Trials

11 recruitingLast updated: July 25, 2026

There are 11 actively recruiting amputee clinical trials across 4 countries. Studies span Not Applicable, Early Phase 1. Top locations include Cleveland, Ohio, United States, Jacksonville, Florida, United States, Islamabad, Punjab Province, Pakistan. Updated daily from ClinicalTrials.gov.


Amputee Trials at a Glance

11 actively recruiting trials for amputee are listed on ClinicalTrialsFinder across 6 cities in 4 countries. The largest study group is Not Applicable with 10 trials, with the heaviest enrollment activity in Cleveland, Jacksonville, and Islamabad. Lead sponsors running amputee studies include VA Office of Research and Development, Centre Hospitalier Universitaire de Saint Etienne, and Centre Hospitalier Universitaire de Nīmes.

Browse amputee trials by phase

Treatments under study

About Amputee Clinical Trials

Looking for clinical trials for Amputee? There are currently 3 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Amputee trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Amputee clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 111 of 11 trials

Recruiting
Not Applicable

Peripheral Interfaces in Amputees for Sensorimotor Integration

Upper Extremity Amputee
VA Office of Research and Development15 enrolled2 locationsNCT04430218
Recruiting
Not Applicable

Functional and Neuroprotective Effects of Restoring Lower Limb Sensation After Diabetic Peripheral Neuropathy

Diabetic Peripheral NeuropathyLower Extremity Amputee
VA Office of Research and Development15 enrolled1 locationNCT04658693
Recruiting
Not Applicable

Bio Leg: Advancing Mobility (BAM)

AmputeeAmputationAmputation of Lower Limb Above Knee
University of Florida12 enrolled1 locationNCT07613502
Recruiting
Not Applicable

Dynamic Balance in Unilateral Transtibial Amputees Following Virtual Reality Versus Conventional Rehabilitation

Virtual RealityPostural BalanceAmputees / Rehabilitation
Centre Hospitalier Universitaire de Nīmes20 enrolled2 locationsNCT06424249
Recruiting
Not Applicable

Proprioceptive Sensorimotor Integration With Neural Interfaces for Hand Prostheses

Upper Limb Amputees
VA Office of Research and Development8 enrolled1 locationNCT04947462
Recruiting
Not Applicable

Impairment Oriented Versus Task Oriented Gait Training In Transfemoral Amputee Rehabilitation.

Transfemoral Amputees
Foundation University Islamabad40 enrolled1 locationNCT07578051
Recruiting
Not Applicable

Evaluation of a Multimodal Tactile Feedback System for Upper Limb-loss Users: Embodiment and Performance

Amputees
University of Pisa9 enrolled1 locationNCT07418645
Recruiting
Not Applicable

Effect of Neuro20 Functional Electrical Stimulation Suit on Autonomic Function, Muscle Performance, and Gait

StrokeSpinal Cord InjuryAmputees
Brooks Rehabilitation30 enrolled2 locationsNCT07164846
Recruiting
Early Phase 1

Feasibility Study Evaluating the Safety and Effectiveness of Magnetic Bead Tracking System When Used With a Bionic External Prosthesis

Transtibial amputationTranstibial Amputee
MuscleMetrix, LLC3 enrolled1 locationNCT07195461
Recruiting
Not Applicable

Evaluation of the Biomechanics of Crowding and the Energetic Cost of Endurance Runners Unilateral Transtibial Amputees.

AmputeeHealthy VolunteersProstheses
Centre Hospitalier Universitaire de Saint Etienne24 enrolled1 locationNCT06948695
Recruiting
Not Applicable

Strategies to Control Robotic Hand Prosthesis Via HD-sEMG and to Restore Sensory Feedback Via TENS

Upper Limb Amputees
Istituto Nazionale Assicurazione contro gli Infortuni sul Lavoro30 enrolled1 locationNCT06486571