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Healthy Volunteers Clinical Trials

258 recruitingLast updated: July 17, 2026

There are 258 actively recruiting healthy volunteers clinical trials across 41 countries. Studies span Phase 1, Not Applicable, Phase 2, Early Phase 1, Phase 3, Phase 4. Top locations include Bethesda, Maryland, United States, Baltimore, Maryland, United States, London, United Kingdom. Updated daily from ClinicalTrials.gov.


Healthy Volunteers Trials at a Glance

258 actively recruiting trials for healthy volunteers are listed on ClinicalTrialsFinder across 6 cities in 41 countries. The largest study group is Phase 1 with 129 trials, with the heaviest enrollment activity in Bethesda, Baltimore, and London. Lead sponsors running healthy volunteers studies include Bristol-Myers Squibb, AbbVie, and Hospices Civils de Lyon.

Browse healthy volunteers trials by phase

Treatments under study

About Healthy Volunteers Clinical Trials

Looking for clinical trials for Healthy Volunteers? There are currently 227 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Healthy Volunteers trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Healthy Volunteers clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 258 trials

Recruiting
Phase 2

Neurobiology of Suicide

DepressionHealthy Volunteers
National Institute of Mental Health (NIMH)325 enrolled1 locationNCT02543983
Recruiting
Phase 1

A Study of Intravenous CPTX2309 in Healthy Participants and Participants With Moderate to Severe Rheumatoid Arthritis (RA) or Systemic Lupus Erythematosus (SLE)

Rheumatoid ArthritisHealthy VolunteersSystemic Lupus Erythematosus
Capstan Therapeutics64 enrolled3 locationsNCT06917742
Recruiting
Not Applicable

Neural and Psychological Mechanisms of Pain Perception

PainHealthy VolunteersNormal Physiology
National Center for Complementary and Integrative Health (NCCIH)550 enrolled1 locationNCT02446262
Recruiting
Phase 1

A Study to See How RO7763505 Works and How Safe it is When Given to Healthy People and People With Stable Heart Disease

stable coronary artery diseaseHealthy Volunteers
Hoffmann-La Roche196 enrolled1 locationNCT07495813
Recruiting
Phase 1

A Positron Emission Tomography Study to Assess the Occupancy of M4 Muscarinic Acetylcholine Receptors by BMS-986521 in Healthy Adult Participants

Healthy Volunteers
Bristol-Myers Squibb12 enrolled1 locationNCT07655518
Recruiting

Children s Growth and Behavior Study

ObesityHealthy VolunteersEating Behaviors
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)1,500 enrolled1 locationNCT02390765
Recruiting

Collection and Analysis of Blood, Bone Marrow, and Buccal Mucosa Samples From Healthy Volunteers

Healthy Volunteers
National Heart, Lung, and Blood Institute (NHLBI)1,000 enrolled1 locationNCT00442195
Recruiting

Imaging Techniques in MRI

HealthyHealthy VolunteersCardiac Risk Factors
National Institutes of Health Clinical Center (CC)1,000 enrolled1 locationNCT01130545
Recruiting

Sample Collection From Healthy Volunteers for Assay Optimization

Healthy Volunteers
National Institute of Allergy and Infectious Diseases (NIAID)600 enrolled1 locationNCT03538600
Recruiting
Phase 1

A Study to Investigate the Effect of the CYP3A Inducer Phenytoin and the CYP3A Inhibitor Itraconazole on the Pharmacokinetics of BGB-58067 in Healthy Participants

Healthy Volunteers
BeOne Medicines30 enrolled1 locationNCT07590102
Recruiting

Cytapheresis of Volunteer Donors

Healthy Volunteers
National Institute on Aging (NIA)10,000 enrolled1 locationNCT00104325
Recruiting
Phase 1

A Study to Evaluate Novel KarX and KarT Prototypes Versus the KarXT and KarX-EC Reference Following Single Doses, and to Explore the Effect of Food After Multiple Doses of Selected Prototypes in Healthy Adult Participants

Healthy Volunteers
Bristol-Myers Squibb72 enrolled1 locationNCT07063342
Recruiting
Phase 1

Developing Biomarkers of Dietary Intake: Dose Dependent Measurement of Sugar Intake

Healthy VolunteersDiet Therapy
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)60 enrolled1 locationNCT04799301
Recruiting
Phase 1

A Study to Investigate the Relative Bioavailability and Food Effect of Tablet for Oral Suspension of Sonrotoclax in Healthy Adults

Healthy Volunteers
BeOne Medicines12 enrolled1 locationNCT07628881
Recruiting
Phase 1

A Study of Multiple Doses of Orally Administered RO7795081 in Otherwise Healthy Chinese Adult Participants With Obesity or Overweight

Healthy VolunteersOverweight or Obesity
Hoffmann-La Roche30 enrolled2 locationsNCT07499050
Recruiting
Phase 1

A Phase I Study to Evaluate LIFE-001

Healthy Volunteers
LifeMine Therapeutics160 enrolled1 locationNCT06904807
Recruiting
Phase 1

PET Study to Evaluate Brain Receptor Occupancy, Safety and Pharmacokinetics of ITI-1284 in Healthy Subjects

Healthy Volunteers
Intra-Cellular Therapies, Inc.42 enrolled1 locationNCT06299410
Recruiting
Phase 1Phase 2

A Study to Evaluate BMS-986470 in Healthy Volunteers and Participants With Sickle Cell Disease

Healthy VolunteersAnemia, Sickle Cell
Bristol-Myers Squibb224 enrolled33 locationsNCT06481306
Recruiting

Genetic and Epigenetic Signatures of Translational Aging Laboratory Testing (GESTALT)

Healthy VolunteersFrailNon-Healthy/Non-Frail
National Institute on Aging (NIA)900 enrolled1 locationNCT02339012
Recruiting
Phase 1

A Study to Assess the Relative Bioavailability of BMS-986435 and Food Effect on the BMS-986435 in Healthy Adult Participants

Healthy Volunteers
Bristol-Myers Squibb140 enrolled1 locationNCT07226817