Phase 1 Anterior cruciate ligament Clinical Trials
4 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–4 of 4 trials
Recruiting
Phase 1
Anterior Cruciate Ligament (ACL) Reconstruction With Autologous Fat Pad Derived Mesenchymal Stem Cells
Anterior cruciate ligament reconstruction
The Methodist Hospital Research Institute15 enrolled1 locationNCT06798623
Not Yet Recruiting
Phase 1
Safety and Efficacy of IntraOsseous Ropivacaine in Lower Extremity (SORE) Study
Anterior cruciate ligament reconstruction
Simon Young15 enrolled1 locationACTRN12619000700134
Completed
Phase 1
A randomised, double-blind, comparator study to assess the safety & tolerability of a single injection into the knee joint of MSB-CAR001 when combined with Hyaluronan compared to Hyaluronan alone in patients who have recently undergone an Anterior Cruciate Ligament Reconstruction.
Anterior Cruciate Ligament (ACL) reconstruction following an initial, unilateral acute ACL injury.Osteoarthritis post ACL repair
Mesoblast Ltd24 enrolled1 locationACTRN12609001018202
Recruiting
Phase 1
An evaluation of knee stability and functions following ACL reconstruction (semitendinosus/gracillis grafts) comparing manually versus mechanically tensioned grafts (using a tensioning device).
Knees requiring ACL-Anterior Cruciate Ligament reconstruction
Queensland Health50 enrolled1 locationACTRN12606000389505