Phase 3 Antibiotic Clinical Trials

10 recruitingPhase 3

What is a Phase 3 trial?

Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.

Showing 110 of 10 trials

Recruiting
Phase 3

Local Antibiotics for Breast Implants

Implant ComplicationImplant InfectionAntibiotic Side Effect+4 more
Mikkel Herly1,003 enrolled8 locationsNCT04731025
Recruiting
Phase 3

PO vs IV Antibiotics for the Treatment of Infected Nonunion of Fractures After Fixation

InfectionsInjury LegAmputation+6 more
Major Extremity Trauma Research Consortium250 enrolled13 locationsNCT05699174
Recruiting
Phase 3

The MANTRA Trial (MANdibular TRauma and Antibiotic Use)

Mandible FracturePost-operative Antibiotics
East Lancashire Hospitals NHS Trust2,841 enrolled2 locationsNCT05964140
Recruiting
Phase 2Phase 3

Antibiotic Impregnated Bone Graft to Reduce Infection in Hip Replacement.

Antibiotic Resistant InfectionOsteoarthritis, HipProsthetic joint infection+1 more
University Hospital, Linkoeping1,100 enrolled1 locationNCT05169229
Recruiting
Phase 3

Broad-spectrum Antibiotic Prophylaxis in Tumor and Infected Orthopedic Surgery

Surgical Site InfectionMicrobial ColonizationAntibiotic Resistant Infection
Balgrist University Hospital1,100 enrolled1 locationNCT05502380
Recruiting
Phase 3

The Role of Antibiotic Prophylaxis in Lowering Wound Infection Rates Post-Open Repair of Primary Elective Groin Hernias in High-Risk Patients

Groin HerniaAntibiotic ProphylaxisWound Infection
University of Aleppo200 enrolled1 locationNCT06576154
Recruiting
Phase 3

Intermittent Cefoxitin Administration Versus Loading Bolus Followed by Continuous Infusion for the Prevention of Surgical Site Infection in Colorectal Surgery

Colorectal SurgeryAntibiotic Prophylaxis
Poitiers University Hospital2,000 enrolled19 locationsNCT05755789
Recruiting
Phase 3

Pivmecillinam With Amoxicillin/Clavulanic Acid for Step Down Oral Therapy in ESBL UTIs

BacteremiaUrinary Tract InfectionsAntibiotic Resistant Infection
Lund University330 enrolled5 locationsNCT05224401
Completed
Phase 3Phase 4

Prophylactic antibiotic in patients who undergo cystoscopy with urine sterile: a double blind controlled clinical trial

prophylactic antibiotic use in cystoscopy to decrease the incidence of urinary tract infection
Herney Garcia300 enrolled2 locationsACTRN12611000750987
Completed
Phase 3

International neonatal immunotherapy study

Infants with sepsis. Infants being treated with antibiotics are eligible. Infants can be preterm or term.
The University of Sydney5,000 enrolled1 locationACTRN12606000273583