Early Phase 1 APL Clinical Trials

8 recruitingEarly Phase 1

What is a Early Phase 1 trial?

Early Phase 1 trials are the earliest stage of testing in humans. These small studies focus on how a drug is processed in the body and how it affects the body, often enrolling just a handful of participants to establish initial safety data.

Showing 18 of 8 trials

Recruiting
Early Phase 1

MEP Up-conditioning to Target Corticospinal Plasticity

Spinal Cord InjuryTetraplegia/Tetraparesis
Medical University of South Carolina11 enrolled1 locationNCT06989905
Recruiting
Early Phase 1

Lorlatinib for Newly-Diagnosed High-Grade Glioma With ROS or ALK Fusion

GlioblastomaGlioblastoma MultiformeHigh Grade Glioma+6 more
Nationwide Children's Hospital15 enrolled18 locationsNCT06333899
Recruiting
Early Phase 1

[177Lu]Lu-AKIR001 First-in-human Study

Thyroid Gland Anaplastic CarcinomaPoorly Differentiated Thyroid CarcinomaCancer Head and Neck+3 more
Karolinska University Hospital15 enrolled1 locationNCT06639191
Recruiting
Early Phase 1

Darzalex Faspro (Daratumumab and Hyaluronidase-fihj) Before Standard Desensitization and Allogeneic Peripheral Blood Stem Cell Transplantation in Adult Patients at High-risk for Primary Graft Failure Secondary to Donor Specific Antibodies

Multiple MyelomaLymphomaHematologic Malignancy+5 more
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins8 enrolled1 locationNCT06398457
Recruiting
Early Phase 1

Implantable Microdevice In Primary Brain Tumors

GlioblastomaAstrocytomaGrade II Glioma+5 more
Oliver Jonas12 enrolled1 locationNCT04135807
Recruiting
Early Phase 1

Spinal Cord Associative Plasticity Study

Cervical Spinal Cord InjuryCervical MyelopathyTetraplegia/Tetraparesis
Columbia University92 enrolled3 locationsNCT05163639
Recruiting
Early Phase 1

CD7 CAR-T Bridging to alloHSCT for Severe Aplastic Anemia

Aplastic Anemia
Zhejiang University30 enrolled1 locationNCT06633328
Recruiting
Early Phase 1

Calcium Folinate Treatment of Spastic Paraplegia 56

Hereditary Spastic Paraplegia
Shanghai 6th People's Hospital10 enrolled1 locationNCT06478238