Arterial calcification Clinical Trials

7 recruitingLast updated: May 13, 2026

There are 7 actively recruiting arterial calcification clinical trials across 12 countries. Studies span Phase 1, Phase 2, Phase 3. Top locations include Paris, France, Manchester, United Kingdom, Bethesda, Maryland, United States. Updated daily from ClinicalTrials.gov.


Arterial calcification Trials at a Glance

7 actively recruiting trials for arterial calcification are listed on ClinicalTrialsFinder across 6 cities in 12 countries. The largest study group is Phase 1 with 1 trial, with the heaviest enrollment activity in Paris, Manchester, and Bethesda. Lead sponsors running arterial calcification studies include Inozyme Pharma, National Human Genome Research Institute (NHGRI), and Royal Perth Hospital.

Browse arterial calcification trials by phase

Treatments under study

About Arterial calcification Clinical Trials

Looking for clinical trials for Arterial calcification? There are currently 2 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Arterial calcification trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Arterial calcification clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 17 of 7 trials

Recruiting

Diagnosis and Treatment of Patients With Inborn Errors of Metabolism

Arterial Calcification Due to Deficiency of CD73
National Human Genome Research Institute (NHGRI)4,000 enrolled1 locationNCT00369421
Recruiting
Phase 1

The ENERGY Study: Evaluation of Safety and Tolerability of INZ-701 in Infants With ENPP1 Deficiency or ABCC6 Deficiency

Pseudoxanthoma ElasticumEctonucleotide Pyrophosphatase/phosphodiesterase1 DeficiencyAutosomal Recessive Hypophosphatemic Rickets+2 more
Inozyme Pharma16 enrolled7 locationsNCT05734196
Recruiting
Phase 3

ENERGY 2: Evaluation of the Efficacy and Safety of INZ-701 in Infants With ENPP1 Deficiency

Ectonucleotide Pyrophosphatase/phosphodiesterase1 DeficiencyAutosomal Recessive Hypophosphatemic RicketsGeneralized Arterial Calcification of Infancy 1
Inozyme Pharma12 enrolled8 locationsNCT07473973
Recruiting

CRUSH PAD: Real-world Outcomes Following Use of Shockwave Intravascular Lithotripsy (IVL) Technology in Calcified Common Femoral Lesions

ClaudicationPeripheral Arterial DiseaseFemoral Arterial Calcification+1 more
Yale University50 enrolled2 locationsNCT05145478
Recruiting

The Correlation of Intracranial Artery Calcification and Outcomes of Mechanical Thrombectomy

Brain DiseasesCentral Nervous System DiseasesStroke+6 more
Zhujiang Hospital434 enrolled1 locationNCT06418698
Recruiting
Phase 2

ADAPT Study: Long-term Safety Study of INZ-701 in Patients With ENPP1 Deficiency and ABCC6 Deficiency

Arterial calcificationPseudoxanthoma ElasticumEctonucleotide Pyrophosphatase/phosphodiesterase1 Deficiency+2 more
Inozyme Pharma200 enrolled5 locationsNCT06462547
Recruiting

The feasibility of 18F-Fluoromisonidazole (18F-FMISO) imaging for atherosclerotic and non-atherosclerotic intra-arterial hypoxia.

Arterial calcificationCardiovascular Disease
Royal Perth Hospital12 enrolled1 locationACTRN12622000442707