Atrophy Clinical Trials in Nashville, Tennessee

16 recruitingNashville, Tennessee

Showing 116 of 16 trials

Recruiting

A Study to Learn How Avacincaptad Pegol (Izervay™) is Used in Clinical Practice in People Who Have Geographic Atrophy

Geographic AtrophyMacular Degeneration
Astellas Pharma Global Development, Inc.500 enrolled65 locationsNCT06779773
Recruiting
Phase 2

A Trial to Test if TEV-56286 is Effective for Treatment of Participants With Multiple System Atrophy

Multiple System Atrophy
Teva Branded Pharmaceutical Products R&D LLC350 enrolled58 locationsNCT06568237
Recruiting

Natural History Study of Synucleinopathies

Multiple System AtrophyParkinson DiseaseDementia With Lewy Bodies+5 more
NYU Langone Health800 enrolled8 locationsNCT01799915
Recruiting
Phase 2

A Phase 2, Randomized, Placebo Controlled, Multicenter, Masked Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacodynamics of Multidose APL 3007 in Combination With Syfovre/Pegcetacoplan (APL-2) in Patients Diagnosed With Geographic Atrophy Secondary to Age Related Macular Degeneratio

Geographic Atrophy secondary to Age Related Macular Degeneration
Apellis Pharmaceuticals, Inc.240 enrolled68 locationsNCT07215390
Recruiting
Phase 3

A Study Investigating Subcutaneously Administered Pozelimab in Combination With Cemdisiran or Cemdisiran Alone in Adult Participants With Geographic Atrophy

Age related macular degeneration (AMD)Geographic Atrophy (GA)
Regeneron Pharmaceuticals975 enrolled216 locationsNCT06541704
Recruiting
Phase 2

A Study to Optimize Subretinal Surgical Delivery and to Evaluate Safety and Activity of Opregen in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration (GAlette); Adaptive Optics (AO) Retinal Imaging Substudy in Association With Study GR44251

Geographic Atrophy
Genentech, Inc.60 enrolled17 locationsNCT05626114
Recruiting
Phase 2

A Phase 2 Study of YA-101 in Patients With Multiple System Atrophy

Multiple System Atrophy
Dasher Neuroscience Inc.75 enrolled9 locationsNCT06848231
Recruiting
Phase 1

A Study to Investigate Safety, Tolerability, Pharmacokinetics (PK), Pharmacodynamics (PD), and Immunogenicity of RO7669330 in Participants With Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD)

Geographic Atrophy
Hoffmann-La Roche132 enrolled16 locationsNCT06961370
Recruiting
Not Applicable

CPAP for the Treatment of Supine Hypertension

Multiple System AtrophyParkinson DiseaseAutonomic Failure+3 more
Vanderbilt University Medical Center59 enrolled1 locationNCT05489575
Recruiting
Phase 1

[18F]F-DOPA Imaging in Patients With Autonomic Failure

Multiple System AtrophyParkinson DiseaseDementia With Lewy Bodies+2 more
Daniel Claassen40 enrolled1 locationNCT04246437
Recruiting
Not Applicable

Overnight Trials With Heat Stress in Autonomic Failure Patients With Supine Hypertension

HypertensionMultiple System AtrophyAutonomic Failure+1 more
Vanderbilt University Medical Center20 enrolled1 locationNCT03042988
Recruiting
Phase 1

Hemodynamic Mechanisms of Abdominal Compression in the Treatment of Orthostatic Hypotension in Autonomic Failure

Multiple System AtrophyAutonomic FailurePure Autonomic Failure+1 more
Vanderbilt University Medical Center29 enrolled1 locationNCT02429557
Recruiting
Early Phase 1

Effect of Midodrine vs Abdominal Compression on Cardiovascular Risk Markers in Autonomic Failure Patients

Multiple System AtrophyParkinson DiseaseAutonomic Failure+2 more
Vanderbilt University Medical Center31 enrolled1 locationNCT04620382
Recruiting
Phase 1Phase 2

Automated Abdominal Binder for Orthostatic Hypotension

Multiple System AtrophyAutonomic FailurePure Autonomic Failure+1 more
Vanderbilt University Medical Center31 enrolled1 locationNCT03482297
Recruiting
Phase 1

Effects of Midodrine and Droxidopa on Splanchnic Capacitance in Autonomic Failure

Multiple System AtrophyParkinson DiseaseAutonomic Failure+2 more
Vanderbilt University Medical Center34 enrolled1 locationNCT02897063
Recruiting
Not Applicable

Use of Accelerometer for Quantification of Neurogenic Orthostatic Hypotension Symptoms

Multiple System AtrophyAutonomic FailurePure Autonomic Failure+2 more
Vanderbilt University Medical Center29 enrolled1 locationNCT04782830