Atrophy Clinical Trials

2 recruiting

Atrophy Trials at a Glance

220 actively recruiting trials for atrophy are listed on ClinicalTrialsFinder across 6 cities in 54 countries. The largest study group is Not Applicable with 76 trials, with the heaviest enrollment activity in New York, Boston, and Dallas. Lead sponsors running atrophy studies include Vanderbilt University Medical Center, Biogen, and Hoffmann-La Roche.

Treatments under study

About Atrophy Clinical Trials

Looking for clinical trials for Atrophy? There are currently 2 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Atrophy trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Atrophy clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 220 trials

Recruiting
Phase 2

A Study to Evaluate How Apitegromab Works in Subjects Who Are Less Than 2 Years Old and Have Spinal Muscular Atrophy

Spinal Muscular AtrophySMASpinal Muscular Atrophy Type 3+3 more
Scholar Rock, Inc.52 enrolled25 locationsNCT07047144
Recruiting
Not Applicable

Efficacy and Safety of Transcranial dIrect Current stiMulation in Multiple System Atrophy-Cerebellar Variant

Multiple System Atrophy - Cerebellar Subtype (MSA-C)
University of Salerno30 enrolled1 locationNCT06821256
Recruiting

Natural History of Glycosphingolipid Storage Disorders and Glycoprotein Disorders

MyoclonusNeurological RegressionCherry Red Spot+1 more
National Human Genome Research Institute (NHGRI)200 enrolled1 locationNCT00029965
Recruiting
Phase 2

A Phase 2 Study of YA-101 in Patients With Multiple System Atrophy

Multiple System Atrophy
Dasher Neuroscience Inc.75 enrolled9 locationsNCT06848231
Recruiting
Phase 3

Testing Laser Therapy for Treatment of Vaginal Dryness in Survivors of Breast Cancer, The Revitalize Trial

Anatomic Stage II Breast Cancer AJCC v8Anatomic Stage III Breast Cancer AJCC v8Anatomic Stage 0 Breast Cancer AJCC v8+9 more
Alliance for Clinical Trials in Oncology250 enrolled1 locationNCT05379153
Recruiting
Phase 1

Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of ION464 Administered to Adults With Multiple System Atrophy (HORIZON)

Multiple System Atrophy
Ionis Pharmaceuticals, Inc.40 enrolled15 locationsNCT04165486
Recruiting
Not Applicable

Comprehensive Swallowing Rehabilitation in Patients With MSA

Multiple System Atrophy
Seoul National University Hospital24 enrolled1 locationNCT04782284
Recruiting
Phase 1

Intravitreal (IVT) Pozelimab for Geographic Atrophy (GA) in Adult Participants

Geographic Atrophy (GA)
Regeneron Pharmaceuticals54 enrolled5 locationsNCT07230834
Recruiting

Central micrOperimetry and Radial OCT Evaluation in Geographic Atrophy (CORE-GA): a Prospective Pilot Study

Geographic AtrophyAge-Related Macular Degeneration
University of California, San Francisco80 enrolled1 locationNCT07556406
Recruiting

A Study to Learn How Avacincaptad Pegol (Izervay™) is Used in Clinical Practice in People Who Have Geographic Atrophy

Geographic AtrophyMacular Degeneration
Astellas Pharma Global Development, Inc.1,000 enrolled65 locationsNCT06779773
Recruiting

Development of Non-Invasive Prenatal Diagnosis for Single Gene Disorders

Cystic FibrosisHuntington DiseaseSickle Cell Disease+12 more
Assistance Publique - Hôpitaux de Paris550 enrolled1 locationNCT06147414
Recruiting
Phase 1Phase 2

A Safety and Efficacy Study of a One-time Intravitreal Injection of SAR446597 in Participants With Geographic Atrophy Secondary to Age-related Macular Degeneration

Geographic Atrophy
Sanofi104 enrolled17 locationsNCT07215234
Recruiting
Phase 2

A Study to Optimize Subretinal Surgical Delivery and to Evaluate Safety and Activity of Opregen in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration (GAlette); Adaptive Optics (AO) Retinal Imaging Substudy in Association With Study GR44251

Geographic Atrophy
Genentech, Inc.60 enrolled17 locationsNCT05626114
Recruiting
Phase 2

A Study to Assess the Safety, Tolerability, Efficacy, Pharmacokinetics, and Immunogenicity of Intravenous Administration of ARGX-119 in Pediatric Participants Aged 5 to Less Than 18 Years With Spinal Muscular Atrophy

Spinal Muscular Atrophy (SMA)
argenx60 enrolled17 locationsNCT07287982
Recruiting
Phase 2

An Extension Trial to Test if TEV-56286 is Effective in Relieving Multiple System Atrophy

Multiple System Atrophy
Teva Branded Pharmaceutical Products R&D LLC200 enrolled15 locationsNCT07197866
Recruiting
Phase 2

A Trial to Test if TEV-56286 is Effective for Treatment of Participants With Multiple System Atrophy

Multiple System Atrophy
Teva Branded Pharmaceutical Products R&D LLC350 enrolled54 locationsNCT06568237
Recruiting
Phase 3

A Study to Learn About Salanersen's (BIIB115) Effects on Movement and Its Safety in Participants Aged 15 to 60 Years With Spinal Muscular Atrophy (SMA) Who Are Either New to SMA Treatment or Were Previously Treated With Risdiplam

Spinal Muscular Atrophy
Biogen90 enrolled1 locationNCT07444476
Recruiting

Invasive Home Ventilation in Denmark

Spinal Cord Injuries (SCI)Neuromuscular Diseases (NMD)MSA - Multiple System Atrophy+5 more
Rigshospitalet, Denmark450 enrolled1 locationNCT07467187
Recruiting

Pain and Autonomic Symptoms in Parkinson's Disease and Atypical Parkinsonisms

Multiple System AtrophyParkinson Disease
Istituti Clinici Scientifici Maugeri SpA280 enrolled9 locationsNCT05748028
Recruiting
Not Applicable

Study of an Intrathecal Port and Catheter System for Subjects With Spinal Muscular Atrophy

Spinal Muscular AtrophyScoliosisSpine Deformity
Alcyone Therapeutics, Inc90 enrolled21 locationsNCT05866419