Phase 3 Atrophy Clinical Trials
11 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–11 of 11 trials
Recruiting
Phase 3
A Study to Learn About Salanersen's (BIIB115) Effects on Movement and Its Safety When Given Before Symptoms Appear in Babies With Genetically Diagnosed Spinal Muscular Atrophy (SMA)
Muscular Atrophy, Spinal
Biogen30 enrolled4 locationsNCT07221669
Recruiting
Phase 3
A Study Investigating Subcutaneously Administered Pozelimab in Combination With Cemdisiran or Cemdisiran Alone in Adult Participants With Geographic Atrophy
Age related macular degeneration (AMD)Geographic Atrophy (GA)
Regeneron Pharmaceuticals975 enrolled216 locationsNCT06541704
Recruiting
Phase 3
Testing Laser Therapy for Treatment of Vaginal Dryness in Survivors of Breast Cancer, The Revitalize Trial
Anatomic Stage II Breast Cancer AJCC v8Anatomic Stage III Breast Cancer AJCC v8Anatomic Stage 0 Breast Cancer AJCC v8+9 more
Alliance for Clinical Trials in Oncology250 enrolled2 locationsNCT05379153
Recruiting
Phase 3
A Study to Learn About Salanersen's (BIIB115) Effects on Movement and Its Safety in Participants Aged 15 to 60 Years With Spinal Muscular Atrophy (SMA) Who Are Either New to SMA Treatment or Were Previously Treated With Risdiplam
Spinal Muscular Atrophy
Biogen90 enrolled1 locationNCT07444476
Recruiting
Phase 3
MSA-01 in Multiple System Atrophy
Multiple System Atrophy (MSA)
Tokyo University140 enrolled12 locationsNCT07446894
Recruiting
Phase 3
Long-term Follow-up of Patients With Spinal Muscular Atrophy Treated With OAV101 in Clinical Trials
Spinal Muscular Atrophy (SMA)
Novartis Pharmaceuticals175 enrolled32 locationsNCT05335876
Recruiting
Phase 3
Real World Clinical Effectiveness & Safety of Vesemnogene Lantuparvovec for Spinal Muscular Atrophy (SMA) in Low-middle Income Countries (LMIC).
Spinal Muscular Atrophy (SMA)
Lantu Biopharma15 enrolled1 locationNCT07265232
Recruiting
Phase 3
Safety and Efficacy Evaluation of GC101 Gene Therapy Via Intrathecal (IT) Injectionin the Treatment of Patients With Type 2 Spinal Muscular Atrophy (SMA) - Phase III
SMA - Spinal Muscular Atrophy
GeneCradle Inc50 enrolled7 locationsNCT06971094
Recruiting
Phase 2Phase 3
Clinical Trial of Mexiletine Hydrochloride for Spinal and Bulbar Muscular Atrophy
Spinal and Bulbar Muscular Atrophy
Masahisa Katsuno68 enrolled5 locationsNCT06862596
Recruiting
Phase 2Phase 3
[18F]-MFBG Versus [123I]-MIBG and [18F]-PE2I in PD vs. MSA and DLB vs. AD
Alzheimer DiseaseParkinson DiseaseDementia With Lewy Bodies+1 more
prof. dr. Koen Van Laere113 enrolled2 locationsNCT06120049
Completed
Phase 3Phase 4
A randomised, controlled comparison of uridine, pravastatin or uridine plus pravastatin to accelerate recovery of lipoatrophy in Human immunodeficiency virus (HIV)-infected adults
lipoatrophyHIV
St Vincent's Hospital , Sydney40 enrolled1 locationACTRN12608000307303