Phase 2 Beta-Thalassemia Clinical Trials

7 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 17 of 7 trials

Recruiting
Phase 1Phase 2

Partial Stem Cell Transplant for Sickle Cell Disease From Matched Donors

Beta-ThalassemiaSickle Cell Disease
National Heart, Lung, and Blood Institute (NHLBI)90 enrolled1 locationNCT07599176
Recruiting
Phase 1Phase 2

ALS20-101 Lentiviral Gene Therapy for Beta Thalassemia

Beta-Thalassemia
Children's Hospital of Philadelphia12 enrolled1 locationNCT06364774
Recruiting
Phase 2

A Study to Test the Safety, Tolerability, and Efficacy of an Antibody, REGN7999, Injected Under the Skin for the Treatment of Iron Overload in Adult Participants With Non-Transfusion Dependent β-thalassemia, Using MRI Scans to Measure Iron Levels in the Body

Non-Transfusion Dependent Beta-Thalassemia (NTDT)
Regeneron Pharmaceuticals95 enrolled26 locationsNCT06421636
Recruiting
Phase 2

Study of Safety & PK of Luspatercept (ACE-536) in Pediatric Participants With Beta (β)-Thalassemia

Beta-Thalassemia
Celgene99 enrolled26 locationsNCT04143724
Recruiting
Phase 1Phase 2

An Open-label Study of a Gene Therapy Product (Vebeglogene Autotemcel) in Transfusion Dependent Beta-Thalassemia

Beta-Thalassemia
Lantu Biopharma6 enrolled2 locationsNCT06308159
Recruiting
Phase 2

AlloSCT for Malignant and Non-malignant Hematologic Diseases Utilizing Alpha/Beta T Cell and CD19+ B Cell Depletion

Hodgkin LymphomaNon-Hodgkin LymphomaAcute Leukemia+6 more
Mitchell Cairo20 enrolled1 locationNCT04099966
Recruiting
Phase 1Phase 2

Β-Thalassemia Treatment with KL003 Cell Injection

Transfusion Dependent Beta-Thalassemia
Kanglin Biotechnology (Hangzhou) Co., Ltd.41 enrolled2 locationsNCT06280378