Phase 3 Birth Clinical Trials

19 recruitingPhase 3

What is a Phase 3 trial?

Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.

Showing 119 of 19 trials

Recruiting
Phase 3

Asymptomatic Bacteriuria in Pregnancy in Low- and Middle-IncomE Countries

Preterm BirthStillbirthSmall for Gestational Age (SGA)+1 more
NICHD Global Network for Women's and Children's Health1,134 enrolled7 locationsNCT06723392
Not Yet Recruiting
Phase 3

Resuscitation of term or near term infants at birth with air or 100% oxygen (Resair 3) A Randomised Controlled Trial

Resuscitation of depressed term or near term infants at birth
University of Queensland240,000 enrolled9 locationsACTRN12625001364460
Recruiting
Phase 3

Antenatal Melatonin Supplementation for Neuroprotection in Fetal Growth Restriction

Pregnancy PretermFetal Growth RetardationStillbirth and Fetal Death
Monash University336 enrolled12 locationsNCT05651347
Recruiting
Phase 3

Ferric Derisomaltose (Iron Isomaltoside) Versus Iron Sucrose for Treatment of Iron Deficiency in Pregnancy

Iron Deficiency Anaemia in Childbirth
Saskatchewan Health Authority - Regina Area280 enrolled1 locationNCT05251493
Recruiting
Phase 3

Intracervical Balloon Placement With Nitrous Oxide Administration

Induced; BirthLabor Pain
Maimonides Medical Center162 enrolled1 locationNCT06498908
Recruiting
Phase 3

Selective Early Medical Treatment of Patent Ductus Arteriosus in Extremely Low Gestational Age Infants: A Pilot RCT

Patent Ductus Arteriosus After Premature Birth
IWK Health Centre100 enrolled9 locationsNCT05011149
Recruiting
Phase 3

SAINT: Safe Induction of Labor Trial

Induced; BirthPregnancy RelatedLabor Complication
Oslo University Hospital3,000 enrolled5 locationsNCT05719467
Recruiting
Phase 3

Mifepristone versus placebo to increase the rate of spontaneous labour in people with a prior caesarean: A double blind randomised controlled trial (Mi-labourTrial)

vaginal birth after caesarean
University of Auckland168 enrolled1 locationACTRN12624000103561
Active
Phase 3

Efficacy and Demonstration of IntraVenous Iron for Anaemia in pregnancy (EDIVA)

Low birthweightAnaemiaPrematurity
International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b)900 enrolled1 locationACTRN12621000968875
Recruiting
Phase 3

Reducing operative birth for fetal distress in women with small or suboptimally grown infants - The RidStress 2 Randomised Controlled Trial

Small for gestational age infantsOperative birth (caesarean or instrumental birth)Birth asphyxia
Mater Misericordiae Ltd660 enrolled4 locationsACTRN12621000354886
Recruiting
Phase 3Phase 4

Positive End-Expiratory Pressure (PEEP) Levels during Resuscitation of Preterm Infants at Birth (The POLAR Trial).

Preterm Birth
Murdoch Children's Research Institute906 enrolled11 locationsACTRN12618001686291
Active
Phase 3

Targeted Oxygenation in the Respiratory care of Premature Infants at Delivery: Effects on Outcome (TORPIDO 30/60)

Premature infants requiring resuscitation at birth
University of Sydney1,470 enrolled13 locationsACTRN12618000879268
Active
Phase 3

Preventing Lung Disease Using Surfactant + Steroid (The PLUSS Trial)

Extremely preterm birthRespiratory distress syndrome
The Melbourne Children's Trial Centre1,060 enrolled18 locationsACTRN12617000322336
Not Yet Recruiting
Phase 3

Improvement of feeding tolerance by using a new formula in preterm neonates

Feeding tollerance in very low birth weight neonates
University of Rome "La Sapienza"60 enrolled1 locationACTRN12613000481774
Recruiting
Phase 3

Treatment of Patent Ductus Arteriosus with Paracetamol

Patent ductus arteriosus in very low birth weight neonates
Sapienza University of Rome90 enrolled1 locationACTRN12613000289718
Recruiting
Phase 3

Zinc supplementation in very low birth weight neonates

Morbidity in very low birth weight neonatesIntraventricular hemorrhage
“V.Betania” Evangelic Hospital of Naples200 enrolled1 locationACTRN12612000823875
Completed
Phase 2Phase 3

The safety and efficacy of a locally available probiotic in premature infants.

all cause mortality and time to full feeds in preterm very low birthweight neonatesNecrotising Enterocolitis
Womens and Childrens Health Service120 enrolled1 locationACTRN12609000374268
Completed
Phase 3

Australasian Antenatal Study To Evaluate the Role Of Intramuscular Dexamethasone versus Betamethasone prior to preterm birth to increase survival free of childhood neurosensory disability – a randomised controlled trial

Long-term childhood neurosensory disability following antenatal corticosteroids given to women at risk of preterm birth at less than 34 weeks gestatation
Women’s and Children’s Hospital, SA1,499 enrolled1 locationACTRN12608000631303
Completed
Phase 3

Neonatal respiratory distress syndrome after repeat exposure to antenatal corticosteroids: a randomised controlled trial

Women at risk of preterm birth, at less than 32 weeks gestation, who have already received a course of prenatal corticosteroids.
Professor Caroline Crowther980 enrolled1 locationACTRN12606000318583