Phase 4 Birth Clinical Trials
24 recruitingPhase 4
What is a Phase 4 trial?
Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.
Showing 1–20 of 24 trials
Recruiting
Phase 4
Pragmatic Evaluation of Respiratory Distress Syndrome Treatment in Africa
Premature BirthRespiratory Distress Syndrome in Premature InfantSurfactant Deficiency Syndrome Neonatal+1 more
Indiana University1,512 enrolled8 locationsNCT06554522
Recruiting
Phase 4
Comparison of Two Different Doses of Phenylephrine on Oxytocin Hemodynamic Effect
PhenylephrineCesarean Birth
Rawalpindi Medical College112 enrolled1 locationNCT07420127
Recruiting
Phase 4
Improvement of PPROM Management With Prophylactic Antimicrobial Therapy (iPROMPT)
Pregnancy, High RiskPreterm BirthPreterm Premature Rupture of Membrane
Ohio State University56 enrolled2 locationsNCT06396078
Recruiting
Phase 4
Improving Neonatal Health Through Rapid Malaria Testing in Early Pregnancy With High-Sensitivity Diagnostics
PregnancyMalaria,FalciparumMalaria in Pregnancy+1 more
Duke University2,500 enrolled2 locationsNCT05757167
Not Yet Recruiting
Phase 4
The effect of carbetocin compared with oxytocin to reduce placental retention rates in medical abortion: A randomised controlled trial
Retained placentaMedical termination of pregnancyStillbirth
King Edward Memorial Hospital498 enrolled1 locationACTRN12626000028303
Recruiting
Phase 4
Single Dose of Antenatal Corticosteroids for Pregnancies at Risk of Preterm Delivery (SNACS)
Pregnancy ComplicationsPremature BirthObstetric Labor, Premature+2 more
McMaster University3,254 enrolled25 locationsNCT05114096
Recruiting
Phase 4
Azithromycin and Ampicillin for Late PPROM
Premature BirthAntibiotic ProphylaxisPrematurity+3 more
Sheba Medical Center311 enrolled1 locationNCT07183462
Recruiting
Phase 4
Prophylactic Minimally Invasive Surfactant Evaluation
Premature BirthRespiratory Distress Syndrome, Newborn
Endeavor Health200 enrolled1 locationNCT06007547
Recruiting
Phase 4
Outpatient Antibiotics Following Previable Rupture of Membranes (pPPROM) Between 18 0/7 and 22 6/7 Weeks Gestational Age
Premature BirthPregnancy PretermPregnancy Prom+3 more
University Hospitals Cleveland Medical Center88 enrolled3 locationsNCT05345457
Not Yet Recruiting
Phase 4
A comparison between two differing ways of commencing labour and their effect on duration of labour in women giving birth for the first time.
ChildbirthInduction of labour
Northern Health70 enrolled1 locationACTRN12624001282572
Recruiting
Phase 4
Assessing Interventions to Increase Tdap Acceptance for Non-birthing Partners in Pregnancy
Tdap - Tetanus, Diphtheria and Acellular Pertussis VaccinationNon-birthing Partner Vaccination in PregnancyVaccine Exposure During Pregnancy
Women and Infants Hospital of Rhode Island150 enrolled1 locationNCT06135636
Recruiting
Phase 4
The Effect of an Additional Pre-extubational Loading Dose of Caffeine-citrate
Apnea of PrematurityRespiratory FailurePremature Birth
Semmelweis University226 enrolled2 locationsNCT06401083
Not Yet Recruiting
Phase 4
Does a combination of fluid restriction and the use of oxytocin in a pulsatile fashion (intermittent boluses) for women requiring an induction, result in a reduction in the duration of labour, defined by the commencement of oxytocin until the birth of the neonate, when compared to a regime of fluid restriction with continuous oxytocin?
Labour (induction of)Childbirth
Northern Health412 enrolled1 locationACTRN12623000238673
Not Yet Recruiting
Phase 4
Can Caffeine prevent the cessation of breathing in preterm newborn babies?
Apnea of PrematurityLow Birth WeightPrematurity
Mansoor Aslamzai130 enrolled1 locationACTRN12621001000897
Recruiting
Phase 4
Latency Antibiotics in Previable PPROM, 18 0/7- 22 6/7 WGA
Preterm LaborPreterm BirthRupture of Membranes; Delayed Delivery (Following Spontaneous Rupture)+3 more
Woman's34 enrolled1 locationNCT04047849
Not Yet Recruiting
Phase 4
Perineal Repair Trial. Comparing different types of local anaesthetic for perineal repair following childbirth
Second degree vaginal-perineal tears following birth
Royal Women's Hospital210 enrolled1 locationACTRN12619000056190
Recruiting
Phase 3Phase 4
Positive End-Expiratory Pressure (PEEP) Levels during Resuscitation of Preterm Infants at Birth (The POLAR Trial).
Preterm Birth
Murdoch Children's Research Institute906 enrolled11 locationsACTRN12618001686291
Completed
Phase 4
Warming and humidifying inspiratory gases to minimise lung injury during resuscitation of extremely preterm infants
Extreme preterm birthNewborn resuscitation
Flinders University30 enrolled1 locationACTRN12618000718246
Completed
Phase 4
Comparing two antibiotic regimens for the treatment of late onset sepsis in neonates
Preterm Birth
John Hunter Childrens Hospital50 enrolled1 locationACTRN12618000073202
Not Yet Recruiting
Phase 4
SMOFLipid vs Clinoleic - randomised controlled trial
Patent ductus arteriosisPremature birth- Intra-ventricular haemorrhageParenteral nutrition associated cholestasis and liver disease
Nepean Hospital NICU44 enrolled1 locationACTRN12617000883314