Bone Defect Clinical Trials

12 recruitingLast updated: May 11, 2026

There are 12 actively recruiting bone defect clinical trials across 9 countries. Studies span Not Applicable. Top locations include Barcelos, Portugal, Beirut, Lebanon, Berlin, Germany. Updated daily from ClinicalTrials.gov.


Bone Defect Trials at a Glance

12 actively recruiting trials for bone defect are listed on ClinicalTrialsFinder across 6 cities in 9 countries. The largest study group is Not Applicable with 7 trials, with the heaviest enrollment activity in Barcelos, Beirut, and Berlin. Lead sponsors running bone defect studies include Bioceramed, Beirut Arab University, and Artur Salgado SA.

Browse bone defect trials by phase

About Bone Defect Clinical Trials

Looking for clinical trials for Bone Defect? There are currently 2 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Bone Defect trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Bone Defect clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 112 of 12 trials

Recruiting
Not Applicable

The Use of Two Bone Substitutes in Adjunct to EMD for the Treatment of One- and Two-wall Intrabony Defects.

PeriodontitisBone Defects
I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio40 enrolled1 locationNCT07546279
Recruiting
Not Applicable

FlexiOss® - Efficacy, Safety and Long-term (Radiological and Clinical) Outcomes During Comprehensive Care Continuum of Implanted Biocomposite for Bone Regeneration.

Bone Defect
Medical Inventi S.A.80 enrolled2 locationsNCT07209033
Recruiting

Evaluation of the Safety and Performance of the Neocement® Inject P

Bone DefectsOrthopaedic Surgery (30 Minutes or Longer)
Bioceramed80 enrolled1 locationNCT06973239
Recruiting

Evaluation of the Safety and Performance of the Neocement®

Bone DefectsOrthopaedic Surgery (30 Minutes or Longer)
Bioceramed80 enrolled1 locationNCT06973226
Recruiting
Not Applicable

Bone Reconstruction With Autologous Bone Marrow Mesenchymal Stem Cells in Vitro to Repair Long Tubular Bone Defects

Bone DefectDefective Composite RestorationsBone Cysts+1 more
The First Affiliated Hospital of Xinxiang Medical College30 enrolled1 locationNCT07066228
Recruiting
Not Applicable

Guided Bone Regeneration in Lower Posterior Edentulous Arch Using Resorbable or Non Resorbable Membrane.

Guided Bone RegenerationHorizontal Alveolar Bone Defect
Beirut Arab University30 enrolled1 locationNCT07254494
Recruiting

The Role of Granulation Tissue in Periodontal Regeneration

Periodontal DiseasesPeriodontitisPeriodontal Disease+5 more
Riga Stradins University46 enrolled1 locationNCT07254117
Recruiting
Not Applicable

Clinical and Radiographic Assessment After Surgical Treatment of Anterior Shoulder Dislocation

Shoulder instabilityAnterior shoulder dislocationBone Defects
Istituto Ortopedico Rizzoli20 enrolled1 locationNCT04520087
Recruiting
Not Applicable

Study on Safety and Performance of AdvanCore Bone Void Filler

Bone fracturesBone LossBone Graft+1 more
Artur Salgado SA190 enrolled4 locationsNCT06736457
Recruiting

OSsIRIS Study - A Post-market Clinical Follow-up Investigation.

Surgically Created Bone Defects or Bone Defects/Voids Resulting From Traumatic Injury
GreenBone Ortho S.p.A.135 enrolled4 locationsNCT06156904
Recruiting

Multi-center Study on Comprehensive Diagnosis and Treatment of Lower Limb Bone Defect Based on Three-dimensional Printing Technology

Bone Defects
Peking University Third Hospital120 enrolled1 locationNCT06269354
Recruiting
Not Applicable

Efficiency of 3D-printed Implant Versus Autograft for Orbital Reconstruction (TOR-3D)

Significant Bone Defect in the Orbit
Hospices Civils de Lyon92 enrolled1 locationNCT03608280