Phase 2 BRAF V600E Clinical Trials
6 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–6 of 6 trials
Recruiting
Phase 1Phase 2
Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies
Colorectal, CancerColorectal CarcinomaNon-small Cell Lung Cancer+29 more
Institut de Recherches Internationales Servier554 enrolled27 locationsNCT05786924
Recruiting
Phase 2
Hydroxychloroquine in Combination With Encorafenib and Cetuximab or Panitumumab in the Treatment of Metastatic BRAF-mutated Colorectal Cancer Refractory
Colorectal, CancerColorectal Cancer Stage IVStage IV Colorectal Cancer Positive for BRAF V600E Mutation
Northwestern University43 enrolled8 locationsNCT05576896
Recruiting
Phase 2
A Phase II Study of Sintilimab Combined With Ipilimumab N01, Cetuximab and Dabrafenib in Patients With Microsatellite-Stable, BRAF V600E-Mutated Metastatic Colorectal Cancer
Colorectal, CancerBRAF V600ESintilimab+4 more
Tianjin Medical University Cancer Institute and Hospital49 enrolled4 locationsNCT07506109
Recruiting
Phase 2
Encorafenib and biNimetinib Followed by CEmiplimab and FiAnLimab in Patients With BRAF Mutant melanOma and Symptomatic Brain Metastases
Melanoma BRAF V600E/K MutatedMelanoma and Brain Metastases
Grupo Español Multidisciplinar de Melanoma33 enrolled18 locationsNCT06887088
Recruiting
Phase 2
Encorafenib Plus Cetuximab in a Neoadjuvant Setting in Patients With BRAF Mutation Localised Colon or Upper Rectum Cancer
Colorectal, CancerBRAF V600E Mutation Positive
Federation Francophone de Cancerologie Digestive30 enrolled1 locationNCT05706779
Recruiting
Phase 2
Clinical Study of Neoadjuvant Targeted Therapy for Ameloblastoma
BRAF V600E Mutation PositiveAmeloblastoma
Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University12 enrolled1 locationNCT06653517