Phase 4 Breast Clinical Trials

45 recruitingPhase 4

What is a Phase 4 trial?

Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.

Showing 120 of 45 trials

Recruiting
Phase 4

Study Aiming to Compare the Plasma Exposure of the Payload (Free-DXd) in Patients Treated by T-DXd for Locally Advanced or Metastatic Breast Cancer According to Their BMI.

Locally Advanced or Metastatic Breast Cancers
Institut Claudius Regaud210 enrolled11 locationsNCT07195344
Recruiting
Phase 4

A Study to Investigate Mechanisms of Resistance to Breast Cancer Therapies

Breast Cancer
Hoffmann-La Roche320 enrolled28 locationsNCT06274515
Recruiting
Phase 4

A Study of Antibiotic Delivery to Prevent Infection After Breast Tissue Expander Placement

Breast Cancer
Memorial Sloan Kettering Cancer Center392 enrolled7 locationsNCT07220967
Recruiting
Phase 4

Postpartum Vaginal Estrogen for Breastfeeding Patients

BreastfeedingVaginal AtrophyPostpartum Sexual Dysfunction
University Hospitals Cleveland Medical Center100 enrolled1 locationNCT05457972
Recruiting
Phase 4

Pharmacokinetic Study of Skeletal Muscle Area-based Paclitaxel Infusion in Patients With Cancer

Breast CancerEsophageal CancerMetastatic Gastric Cancer
University of Michigan Rogel Cancer Center22 enrolled1 locationNCT05183126
Recruiting
Phase 4

An Investigational Scan (64Cu-DOTA-Trastuzumab PET/MRI) in Imaging Patients With HER2+ Breast Cancer With Brain Metastasis

Anatomic Stage IV Breast Cancer AJCC v8Metastatic Breast CarcinomaMetastatic Malignant Neoplasm in the Brain
City of Hope Medical Center10 enrolled1 locationNCT05376878
Recruiting
Phase 4

Evaluating Dose Timing (Morning vs Evening) of Endocrine-based Therapies in Metastatic Breast and Prostate Cancers

Metastatic Breast CancerMetastatic Prostate Cancer
Ottawa Hospital Research Institute50 enrolled3 locationsNCT07252726
Recruiting
Phase 4

A Study of Revaree Plus in People With Breast Cancer

Breast CancerStage III Breast CancerStage I Breast Cancer+5 more
Memorial Sloan Kettering Cancer Center60 enrolled7 locationsNCT07042581
Recruiting
Phase 4

Effect of HSD3B1 (1245C) Gene Mutation on Treatment of Stage I-III Breast Cancer

Anatomic Stage II Breast Cancer AJCC v8Anatomic Stage III Breast Cancer AJCC v8Anatomic Stage I Breast Cancer AJCC v8+2 more
University of Washington68 enrolled1 locationNCT05183828
Recruiting
Phase 4

Effect of Intravenous and Topical Tranexamic Acid on Drain Output in Breast Reduction Surgery

Breast ReductionsDrain Output After Breast Reduction Surgery
Massachusetts General Hospital160 enrolled1 locationNCT07131592
Recruiting
Phase 4

Abemaciclib Dose Escalation to Maintain Intensity (ADE-MI)

Breast Cancer
University of Illinois at Chicago50 enrolled3 locationsNCT06169371
Recruiting
Phase 4

Neoadjuvant Weekly Paclitaxel and Biomarkers of Therapy Response

Breast Neoplasm Female
University of Wisconsin, Madison50 enrolled2 locationsNCT03096418
Recruiting
Phase 4

Gabapentin And Breast Surgery Decision Architecture Randomization Trial (GABS-DART) Protocol

Breast Cancer
Memorial Sloan Kettering Cancer Center1,896 enrolled7 locationsNCT07308717
Recruiting
Phase 4

Gentle Touch for Post-Mastectomy Lymphedema

Lymphedema, Breast Cancer
I.R.C.C.S. Fondazione Santa Lucia36 enrolled2 locationsNCT07257679
Recruiting
Phase 4

A Trial Comparing Screening Mammography With and Without Assistance From Artificial Intelligence for Breast Cancer Detection and Recall Rates in Adult Patients

Breast Cancer ScreeningArtificial Intelligence (AI)
Jonsson Comprehensive Cancer Center400,000 enrolled6 locationsNCT06934239
Recruiting
Phase 4

Intrathecal Chemotherapy Through Ommaya Reservoir Upon Her-2 Negative Breast Cancer With Leptomeningeal Metastasis

HER2-negative Breast CancerLeptomeningeal Metastasis
Fudan University37 enrolled1 locationNCT06230055
Recruiting
Phase 4

Brain [18F]-FES PET/CT in Patients With Estrogen-Receptor Positive Breast Cancer

Breast CancerBrain Metastases
Weill Medical College of Cornell University20 enrolled1 locationNCT06072807
Recruiting
Phase 4

DPYD Pharmacogenomics and Fluoropyrimidine (FP) Dose-Adjustment

Breast NeoplasmsColorectal NeoplasmsHead and Neck Neoplasms+1 more
Rutgers, The State University of New Jersey100 enrolled12 locationsNCT07158164
Recruiting
Phase 4

Post-mastectomy Recovery: Comparing Preoperative PECS-II Blocks With Intraoperative Pectoral Blocks

Breast CancerMastectomy; Lymphedema
University of Cincinnati100 enrolled1 locationNCT06574022
Recruiting
Phase 4

CEM to Reduce Biopsy Rates for Less Than Highly Suspicious Breast Abnormalities: a Prospective Study

Breast Cancer
Margarita Louise Zuley2,100 enrolled1 locationNCT05206331