Early Phase 1 CAR Clinical Trials
100 recruitingEarly Phase 1
What is a Early Phase 1 trial?
Early Phase 1 trials are the earliest stage of testing in humans. These small studies focus on how a drug is processed in the body and how it affects the body, often enrolling just a handful of participants to establish initial safety data.
Showing 1–20 of 100 trials
Recruiting
Early Phase 1
3D Ultrasound for the Imaging of Lymph Nodes in Patients With Breast Cancer
Breast Carcinoma
Mayo Clinic55 enrolled1 locationNCT05704283
Recruiting
Early Phase 1
The Safety and Efficacy of Allogeneic CD70 CAR-T Therapy in Unresectable or Metastatic Clear Cell Renal Cell Carcinoma
Unresectable or Metastatic Clear Cell Renal Cell Carcinoma
Chinese PLA General Hospital30 enrolled3 locationsNCT07645690
Recruiting
Early Phase 1
Immunological Effects of Vitamin D Replacement Among Black/African American Prostate Cancer Patients
Metastatic Prostate CarcinomaStage IV Prostate Cancer AJCC v8Localized Prostate Carcinoma+1 more
Mayo Clinic220 enrolled2 locationsNCT05045066
Recruiting
Early Phase 1
A Randomized Controlled Trial of Topical 5% Niacinamide for Skin Cancer Prevention in Transplant Recipients
Skin CancerCutaneous Squamous Cell Carcinoma (CSCC)Actinic Keratosis (AK)+1 more
Marissa Lobl20 enrolled2 locationsNCT07286318
Recruiting
Early Phase 1
Exercise as an Immune Adjuvant for Allogeneic Cell Therapies
LymphomaLeukemiaCAR-T Cell Therapy+3 more
University of Arizona200 enrolled1 locationNCT06643221
Recruiting
Early Phase 1
Feasibility Study on the Effect of a Methionine-Reduced Diet on Serum Levels in Pts w/ Solid Tumors
transitional cell carcinomaSoft Tissue SarcomaMelanoma+12 more
University of California, Irvine25 enrolled1 locationNCT07628634
Recruiting
Early Phase 1
Safety and Tolerability Study of 68Ga/177Lu-BRP-020063 in Advanced Solid Tumors
Urothelial Carcinoma (UC)
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine10 enrolled1 locationNCT07439120
Recruiting
Early Phase 1
MUSE-S Headband System for Improving Anxiety and Insomnia Among Breast Cancer Survivors
Breast Carcinoma
Mayo Clinic20 enrolled1 locationNCT06274034
Recruiting
Early Phase 1
Dual Target CAR-T Cell Treatment for Refractory Systemic Lupus Erythematosus (SLE) Patients
CAR-T Cell Therapy
RenJi Hospital18 enrolled1 locationNCT05858684
Recruiting
Early Phase 1
Prospective Screening for Pancreatic Ductal Adenocarcinoma in High-Risk Individuals
Pancreatic CancerPancreatic Ductal AdenocarcinomaPDAC+2 more
Dana-Farber Cancer Institute5,000 enrolled2 locationsNCT06122896
Recruiting
Early Phase 1
CDH17 CAR-T Therapy in Advanced Malignant Solid Tumors
Biliary Tract CancerColorectal CarcinomaGastric Cancer, Metastatic+2 more
Zhejiang University36 enrolled1 locationNCT06937567
Recruiting
Early Phase 1
Active Surveillance and Chemotherapy Before Surgery in Treating Participants With Stage II-III Rectal Cancer
Rectal AdenocarcinomaStage II Rectal Cancer AJCC v8Stage III Rectal Cancer AJCC v8+6 more
M.D. Anderson Cancer Center120 enrolled1 locationNCT03594630
Recruiting
Early Phase 1
A IIT Study of 177Lu-DOTA-SNA040
Advanced Solid Tumors (Such as Gastric Cancer)Advanced Solid Tumors (Such as Adenocarcinoma at the Gastroesophageal Junction)Advanced Solid Tumors (Such as Pancreatic Cancer)+1 more
SmartNuclide Biopharma12 enrolled1 locationNCT07595237
Recruiting
Early Phase 1
Window Trial of Fluorescently Labeled Panitumumab (Panitumumab-IRDye800) in Head and Neck Cancer
HNSCCSCC - Squamous Cell CarcinomaHNSCC,Larynx, Pharynx and Oral Cavity
Vanderbilt-Ingram Cancer Center18 enrolled1 locationNCT06819228
Recruiting
Early Phase 1
Pilot Study of [68Ga]Ga-ABY-025 Imaging in Patients Undergoing Treatment With HER2-targeted Therapy
Metastatic CancerHER2Locally Advanced Cancer+2 more
Vanderbilt-Ingram Cancer Center30 enrolled1 locationNCT06828588
Recruiting
Early Phase 1
Pain Control and Quality of Recovery After Intravenous Methadone Versus Intravenous Remifentanil in Craniotomy Surgery
PainBrain InjuryBrain Tumors+3 more
University of Virginia40 enrolled1 locationNCT06810336
Recruiting
Early Phase 1
Pilot Study of (MR) Imaging With Pyruvate (13C) to Detect High Grade Prostate Cancer
Prostate CancerLocalized Prostate Carcinoma
Ivan de Kouchkovsky, MD80 enrolled1 locationNCT02526368
Recruiting
Early Phase 1
First-in-human Study of the Theranostic Pair [68Ga]Ga DOTA-5G and [177Lu]Lu DOTA-ABM-5G in Pancreatic Cancer
Metastatic Pancreatic CancerLocally Advanced Pancreatic Adenocarcinoma
University of California, Davis30 enrolled1 locationNCT04665947
Recruiting
Early Phase 1
Oral Carnitine in Heart Failure Patients
Heart FailureCarnitine Deficiency
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's20 enrolled1 locationNCT07201714
Recruiting
Early Phase 1
Safety and Feasibility of HIPEC for High-Risk Gallbladder Adenocarcinoma
Gallbladder Adenocarcinoma
West Virginia University10 enrolled1 locationNCT05430035