Early Phase 1 CAR Clinical Trials
89 recruitingEarly Phase 1
What is a Early Phase 1 trial?
Early Phase 1 trials are the earliest stage of testing in humans. These small studies focus on how a drug is processed in the body and how it affects the body, often enrolling just a handful of participants to establish initial safety data.
Showing 1–20 of 89 trials
Recruiting
Early Phase 1
Pilot Study of (MR) Imaging With Pyruvate (13C) to Detect High Grade Prostate Cancer
Prostate CancerLocalized Prostate Carcinoma
Ivan de Kouchkovsky, MD80 enrolled1 locationNCT02526368
Recruiting
Early Phase 1
First-in-human Study of the Theranostic Pair [68Ga]Ga DOTA-5G and [177Lu]Lu DOTA-ABM-5G in Pancreatic Cancer
Metastatic Pancreatic CancerLocally Advanced Pancreatic Adenocarcinoma
University of California, Davis30 enrolled1 locationNCT04665947
Recruiting
Early Phase 1
Oral Carnitine in Heart Failure Patients
Heart FailureCarnitine Deficiency
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's20 enrolled1 locationNCT07201714
Recruiting
Early Phase 1
Safety and Feasibility of HIPEC for High-Risk Gallbladder Adenocarcinoma
Gallbladder Adenocarcinoma
West Virginia University10 enrolled1 locationNCT05430035
Recruiting
Early Phase 1
UCAR T-cell Therapy Targeting CD19/BCMA in Relapsed/Refractory Autoimmune Hemolytic Anemia
AIHA - Warm Autoimmune Hemolytic AnemiaUCART
The Second Hospital of Anhui Medical University15 enrolled1 locationNCT07530380
Recruiting
Early Phase 1
Sensory Tests of Cigarettes for Identification of Flavors in Current Daily Smoking Adults
Cigarette Smoking-Related Carcinoma
Roswell Park Cancer Institute30 enrolled1 locationNCT06816459
Recruiting
Early Phase 1
Adaptive Therapy of Vismodegib in Advanced Basal Cell Carcinoma
Advanced Basal Cell Carcinoma
H. Lee Moffitt Cancer Center and Research Institute34 enrolled1 locationNCT05651828
Recruiting
Early Phase 1
Clinical Study on the EBV CAR-T /TCR-T Cells in the Treatment of Nasopharyngeal Carcinoma
Nasopharyngeal Carcinoma
Fudan University24 enrolled1 locationNCT05587543
Recruiting
Early Phase 1
Neoadjuvant Pembrolizumab and Lenvatinib for Renal Cell Carcinoma
Renal Cell Carcinoma
Abramson Cancer Center at Penn Medicine30 enrolled1 locationNCT05733715
Recruiting
Early Phase 1
OMO-103 for the Treatment of Locally Advanced or Metastatic Pancreatic Ductal Adenocarcinoma
Stage II Pancreatic Cancer AJCC v8Stage III Pancreatic Cancer AJCC v8Stage IV Pancreatic Cancer AJCC v8+2 more
OHSU Knight Cancer Institute12 enrolled1 locationNCT07089940
Recruiting
Early Phase 1
Using a PET Imaging Agent, 18F-Clofarabine (CFA), to Measure Deoxycytidine Kinase Activity in Metastatic Cancer
Metastatic CancerCarcinomaAdenocarcinoma
Roberto Vargas4 enrolled1 locationNCT05065736
Recruiting
Early Phase 1
Fecal Microbial Transplants for the Treatment of Pancreatic Cancer
Pancreatic Ductal Adenocarcinoma
M.D. Anderson Cancer Center10 enrolled1 locationNCT04975217
Recruiting
Early Phase 1
99mTc-PSMA-I&S Biodistribution in Patients With Prostate Cancer
Prostate CarcinomaRecurrent Prostate Carcinoma
Jonsson Comprehensive Cancer Center30 enrolled1 locationNCT04857502
Recruiting
Early Phase 1
Single-tracer Multiparametric PET Imaging
Cardiovascular DiseaseHealthy Subjects
University of California, Davis60 enrolled1 locationNCT06014515
Recruiting
Early Phase 1
Comparing a New PSMA Imaging Agent to MRI for Detecting Prostate Cancer, BEACON Trial
Prostate Carcinoma
Jonsson Comprehensive Cancer Center30 enrolled1 locationNCT07164027
Recruiting
Early Phase 1
Immunological Effects of Vitamin D Replacement Among Black/African American Prostate Cancer Patients
Metastatic Prostate CarcinomaStage IV Prostate Cancer AJCC v8Localized Prostate Carcinoma+1 more
Mayo Clinic220 enrolled2 locationsNCT05045066
Recruiting
Early Phase 1
Impact of Intraoperative ICG on Functional Outc in RARP
Prostate Adenocarcinoma
University of California, Irvine400 enrolled1 locationNCT06446648
Recruiting
Early Phase 1
Targeted Pathway Inhibition in Patients With Pancreatic Cancer
Stage II Pancreatic Cancer AJCC v8Stage III Pancreatic Cancer AJCC v8Stage IV Pancreatic Cancer AJCC v8+5 more
OHSU Knight Cancer Institute90 enrolled1 locationNCT04005690
Recruiting
Early Phase 1
PhI Pilot Study Pafolacianine Inject for Intraoperative Imaging on Outcomes of GI Cancer Peritoneal Carcinomatosis
Peritoneal CarcinomatosisGastrointestinal Cancer
University of California, Irvine10 enrolled1 locationNCT06511037
Recruiting
Early Phase 1
Placebo-controlled Study of Single and Multiple Ascending Doses of UDP-003 in Healthy Human Participants and Patients
Atherosclerotic Cardiovascular DiseaseAcute Coronary Syndromes
Cyclarity Therapeutics, Inc.84 enrolled1 locationNCT06813339