Cardiomyopathy Clinical Trials in Philadelphia, Pennsylvania
18 recruitingPhiladelphia, Pennsylvania
Showing 1–18 of 18 trials
Recruiting
Phase 2Phase 3
A Study of the Efficacy and Safety of Danicamtiv in Participants With Symptomatic Genetic and Familial Dilated Cardiomyopathy
Symptomatic Genetic Dilated Cardiomyopathy
Kardigan, Inc.332 enrolled33 locationsNCT07210723
Recruiting
Phase 2
A Trial to Evaluate the Efficacy and Safety of Ninerafaxstat in Patients With Symptomatic Non-obstructive Hypertrophic Cardiomyopathy
Non-obstructive Hypertrophic Cardiomyopathy
Imbria Pharmaceuticals, Inc.165 enrolled56 locationsNCT07023614
Recruiting
Phase 3
CLEOPATTRA: A Research Study to Look at the Effects of Treatment With a Medicine Called Coramitug (NNC6019-0001) in People With Heart Failure Due to Transthyretin Amyloid (ATTR) Amyloidosis
Transthyretin Amyloid Cardiomyopathy (ATTR CM)
Novo Nordisk A/S1,280 enrolled289 locationsNCT07207811
Recruiting
Phase 3
TRITON-CM: A Study to Evaluate Nucresiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy
Transthyretin Amyloidosis With Cardiomyopathy
Alnylam Pharmaceuticals1,250 enrolled207 locationsNCT07052903
Recruiting
Phase 1
A Phase 1, Dose Escalation Trial of RP-A601 in Subjects With PKP2 Variant-Mediated Arrhythmogenic Cardiomyopathy (PKP2-ACM)
PKP2 Arrhythmogenic Cardiomyopathy (PKP2-ACM)
Rocket Pharmaceuticals Inc.9 enrolled3 locationsNCT05885412
Recruiting
Phase 2Phase 3
A Study to Evaluate the Effect of Aficamten in Pediatric Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy (oHCM).
PediatricSymptomatic Obstructive Hypertrophic Cardiomyopathy
Cytokinetics55 enrolled38 locationsNCT06412666
Recruiting
Phase 3
Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant
CardiomyopathiesAmyloidosisHeart Diseases+3 more
Eidos Therapeutics, a BridgeBio company582 enrolled98 locationsNCT06563895
Recruiting
Phase 3
MAGNITUDE: A Phase 3 Study of NTLA-2001 in Participants With Transthyretin Amyloidosis With Cardiomyopathy (ATTR-CM)
Transthyretin Amyloidosis (ATTR) With Cardiomyopathy
Intellia Therapeutics1,200 enrolled132 locationsNCT06128629
Recruiting
Phase 1Phase 2
Multi-center, Open-label, Single-ascending Dose Study of Safety and Tolerability of TN-201 in Adults With Symptomatic MYBPC3 Mutation-associated HCM
Hypertrophic Cardiomyopathy
Tenaya Therapeutics30 enrolled10 locationsNCT05836259
Recruiting
Phase 3
A Study to Evaluate the Efficacy and Safety of Sotagliflozin in Symptomatic Obstructive and Non-obstructive Hypertrophic Cardiomyopathy
Non-obstructive Hypertrophic CardiomyopathyObstructive Cardiomyopathy, Hypertrophic
Lexicon Pharmaceuticals500 enrolled107 locationsNCT06481891
Recruiting
Early Phase 1
Sodium Glucose Co-transporter (SGLT) Inhibitors in Nonobstructive Hypertrophic Cardiomyopathy
Hypertrophic Cardiomyopathy Without Obstruction
University of Pennsylvania26 enrolled1 locationNCT06433050
Recruiting
Not Applicable
Clinical Evaluation of the AccuCinch® Ventricular Restoration System in Patients Who Present With Symptomatic Heart Failure With Reduced Ejection Fraction (HFrEF): The CORCINCH-HF Study
Heart Failure With Reduced Ejection Fraction (HFrEF)Dilated Cardiomyopathy
Ancora Heart, Inc.400 enrolled132 locationsNCT04331769
Recruiting
Not Applicable
Left vs Left Randomized Clinical Trial
Heart FailureHeart Failure With Reduced Ejection FractionPacing-Induced Cardiomyopathy+4 more
Baylor College of Medicine2,136 enrolled71 locationsNCT05650658
Recruiting
Phase 4
Impact of Bromocriptine on Clinical Outcomes for Peripartum Cardiomyopathy
Peripartum Cardiomyopathy, Postpartum
Dennis M. McNamara, MD, MS250 enrolled64 locationsNCT05180773
Recruiting
VIZ ACCESS HCM - Multi-Site Registry
Hypertrophic Cardiomyopathy
Viz.ai, Inc.500 enrolled3 locationsNCT07103057
Recruiting
Not Applicable
Using the EHR to Advance Genomic Medicine Across a Diverse Health System
ParagangliomaPheochromocytomaGenetic Predisposition+7 more
University of Pennsylvania1,000 enrolled1 locationNCT06377033
Recruiting
International Consortium for Multimodality Phenotyping in Adults With Non-compaction
Non-Compaction Cardiomyopathy
Stanford University600 enrolled5 locationsNCT04424030
Recruiting
Natural History Study in Pediatric Patients With MYBPC3 Mutation-associated Cardiomyopathy
Cardiomyopathy
Tenaya Therapeutics200 enrolled29 locationsNCT05112237