Phase 3 Cardiomyopathy Clinical Trials
15 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–15 of 15 trials
Recruiting
Phase 2Phase 3
A Study of the Efficacy and Safety of Danicamtiv in Participants With Symptomatic Genetic and Familial Dilated Cardiomyopathy
Symptomatic Genetic Dilated Cardiomyopathy
Kardigan, Inc.332 enrolled33 locationsNCT07210723
Recruiting
Phase 3
CLEOPATTRA: A Research Study to Look at the Effects of Treatment With a Medicine Called Coramitug (NNC6019-0001) in People With Heart Failure Due to Transthyretin Amyloid (ATTR) Amyloidosis
Transthyretin Amyloid Cardiomyopathy (ATTR CM)
Novo Nordisk A/S1,280 enrolled289 locationsNCT07207811
Recruiting
Phase 3
TRITON-CM: A Study to Evaluate Nucresiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy
Transthyretin Amyloidosis With Cardiomyopathy
Alnylam Pharmaceuticals1,250 enrolled207 locationsNCT07052903
Recruiting
Phase 3
CMP-MYTHiC Trial and Registry - CardioMyoPathy With MYocarditis THerapy With Colchicine
Heart FailureCardiomyopathiesMyocarditis+2 more
Niguarda Hospital80 enrolled10 locationsNCT06158698
Recruiting
Phase 2Phase 3
A Study to Evaluate the Effect of Aficamten in Pediatric Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy (oHCM).
PediatricSymptomatic Obstructive Hypertrophic Cardiomyopathy
Cytokinetics55 enrolled38 locationsNCT06412666
Recruiting
Phase 3
Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant
CardiomyopathiesAmyloidosisHeart Diseases+3 more
Eidos Therapeutics, a BridgeBio company582 enrolled98 locationsNCT06563895
Recruiting
Phase 3
MAGNITUDE: A Phase 3 Study of NTLA-2001 in Participants With Transthyretin Amyloidosis With Cardiomyopathy (ATTR-CM)
Transthyretin Amyloidosis (ATTR) With Cardiomyopathy
Intellia Therapeutics1,200 enrolled132 locationsNCT06128629
Recruiting
Phase 3
A Study to Evaluate the Efficacy and Safety of Sotagliflozin in Symptomatic Obstructive and Non-obstructive Hypertrophic Cardiomyopathy
Non-obstructive Hypertrophic CardiomyopathyObstructive Cardiomyopathy, Hypertrophic
Lexicon Pharmaceuticals500 enrolled107 locationsNCT06481891
Recruiting
Phase 3
A Phase III Trial of HRS-1893 in Patients With Obstructive Hypertrophic Cardiomyopathy
Obstructive Hypertrophic Cardiomyopathy
Shandong Suncadia Medicine Co., Ltd.216 enrolled1 locationNCT07021976
Recruiting
Phase 3
Bromocriptine in Dilated Cardiomyopathy Among Women of Reproductive Age
Dilated Cardiomyopathy
Jimma University112 enrolled1 locationNCT06250257
Recruiting
Phase 3
Early Treatment With Candesartan vs Placebo in Genetic Carriers of Dilated Cardiomyopathy (EARLY-GENE Trial)
Cardiomyopathy, Dilated
Cristina Avendaño Solá320 enrolled1 locationNCT05321875
Recruiting
Phase 2Phase 3
The Effects of Hydroxychloroquine in Patients with Inflammatory Cardiomyopathy
MyocarditisInflammatory Cardiomyopathy
Tongji Hospital200 enrolled1 locationNCT05961202
Recruiting
Phase 3
Angiotensin Receptor-Neprilysin Inhibition in Chagas Cardiomyopathy With Reduced Ejection Fraction: ANSWER-HF.
Chagas Cardiomyopathy
University of Sao Paulo General Hospital200 enrolled1 locationNCT04853758
Completed
Phase 2Phase 3
Randomized Controlled Study of L-Arginine Blood Cardioplegia Administration in Patients with Reduced Left Ventricular Function Undergoing Coronary Artery Bypass Graft Surgery
Ischaemic cardiomyopathy requiring coronary artery surgery
David Andrews50 enrolled1 locationACTRN12610000203055
Completed
Phase 3
Evaluation of "Early Disease" in Familial Dilated Cardiomyopathy
Familial dilated cardiomyopathy
St Vincent's Hospital, Darlinghurst64 enrolled1 locationACTRN12605000204640