Phase 4 CED Clinical Trials
75 recruitingPhase 4
What is a Phase 4 trial?
Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.
Showing 1–20 of 75 trials
Recruiting
Phase 4
Gadopiclenol vs. Gadobutrol for Dynamic Contrast-Enhanced Pituitary MRI (Magnetic Resonance Imaging)
Contrast Enhanced Images vs. Non-contrast ImagesGadopiclinol Enhanced Images vs. Gadobutrol Enhanced Images
UConn Health10 enrolled1 locationNCT06846853
Recruiting
Phase 4
ctDNA-guided Addition of Ipilimumab to Patients Receiving Nivolumab and Relatlimab
Metastatic MelanomaAdvanced Melanoma
NYU Langone Health90 enrolled1 locationNCT07504796
Recruiting
Phase 4
Mechanistic Clinical Trial Comparing the Pharmacokinetics/Pharmacodynamics of Metoprolol in Heart Failure With Reduced Ejection Fraction Patients With Low vs. High Polygenic Score
Heart Failure With Reduced Ejection Fraction
University of Michigan100 enrolled1 locationNCT07490067
Recruiting
Phase 4
Intraperitoneal Infusion of Analgesic for Postoperative Pain Management
Pain, PostoperativeGynecologic Surgical ProceduresHysterectomy+1 more
Ying Liu120 enrolled2 locationsNCT04130464
Recruiting
Phase 4
Study Aiming to Compare the Plasma Exposure of the Payload (Free-DXd) in Patients Treated by T-DXd for Locally Advanced or Metastatic Breast Cancer According to Their BMI.
Locally Advanced or Metastatic Breast Cancers
Institut Claudius Regaud210 enrolled11 locationsNCT07195344
Recruiting
Phase 4
A Study for the Evaluation of Efficacy and Safety of Prolia® in Participants With Glucocorticoid-induced Osteoporosis in Mainland China
Glucocorticoid-induced Osteoporosis
Amgen100 enrolled16 locationsNCT06588153
Recruiting
Phase 4
RWS of Tunlametinib in NRAS-Mutant Advanced Melanoma
Melanoma Advanced
Fudan University110 enrolled1 locationNCT07445022
Recruiting
Phase 4
Enfortumab Vedotin and Pembrolizumab With Cystectomy and/or Ureterectomy for Locally Advanced or Metastatic Bladder and Upper Urothelial Tract Cancer, CAST-AI Trial
Metastatic Bladder Urothelial CarcinomaStage IV Bladder Cancer AJCC v8Metastatic Renal Pelvis and Ureter Urothelial Carcinoma+4 more
Mayo Clinic75 enrolled1 locationNCT06764095
Recruiting
Phase 4
Vericiguat and Reverse Remodeling Indices in Heart Failure
Heart Failure With Reduced Ejection Fraction (HFrEF)Chronic Heart Failure
University Medical Centre Ljubljana60 enrolled1 locationNCT07405944
Recruiting
Phase 4
Self-Adjusted Nitrous Oxide: A Feasibility Study in the Setting of Vasectomy
Procedural AnxietyProcedural PainPain Catastrophizing
Beth Israel Deaconess Medical Center35 enrolled1 locationNCT05895383
Recruiting
Phase 4
Treatment With Aspirin After Preeclampsia: TAP Trial
Cardiovascular DiseasesHypertensionPregnancy Complications+8 more
Malamo Countouris60 enrolled1 locationNCT06281665
Recruiting
Phase 4
Rimegepant as Preemptive Treatment for Predictable Trigger-Induced Migraine in Adult Patients in the US
MigraineTrigger Induced Migraine
Medstar Health Research Institute60 enrolled1 locationNCT07301008
Recruiting
Phase 4
Topical Anesthesia During Catheter Insertion for Cervical Ripening (TOLERANCE)
Labor, Induced
Bnai Zion Medical Center200 enrolled1 locationNCT07288021
Recruiting
Phase 4
Comparison of Compounded Topical Anesthetics
Procedural Pain
Dartmouth-Hitchcock Medical Center64 enrolled1 locationNCT06569537
Recruiting
Phase 4
Continuous Infusions vs Scheduled Bolus Infusions
Pain, PostoperativeSurgical Procedure, Unspecified
Stanford University240 enrolled1 locationNCT03230565
Recruiting
Phase 4
Single and Twice-daily Dosing of Ramipril on Renal Function in Chronic Kidney Disease Patients With Reduced Ejection Fraction Heart Failure
Chronic Kidney DiseaseHeart Failure With Reduced Ejection Fraction (HFrEF)
Evi Liliek Wulandari80 enrolled1 locationNCT07259512
Recruiting
Phase 4
Effect of Itopride on Semaglutide Gastroparesis
AnesthesiaSemaglutide-Induced Gastric Motility
Ain Shams University60 enrolled1 locationNCT07254715
Recruiting
Phase 4
BMT-08: A Comparative Effectiveness Study of Transdermal Granisetron to Ondansetron
Nausea With Vomiting Chemotherapy-Induced
University of Illinois at Chicago90 enrolled1 locationNCT04150614
Recruiting
Phase 4
Efficacy of Prothrombin Complex Concentrate Reducing Perioperative Blood Loss in Cardiac Surgery
Cardiac Surgical Procedures
SHI Jia820 enrolled2 locationsNCT04244981
Recruiting
Phase 4
Ondansetron Orodispersible Film for Vomiting Prevention in Pediatric Radiotherapy
Pediatric CancerRadiotherapy-induced Nausea and Vomiting (RINV)
Chongqing University Cancer Hospital60 enrolled1 locationNCT07217600