Phase 4 CED Clinical Trials
82 recruitingPhase 4
What is a Phase 4 trial?
Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.
Showing 1–20 of 82 trials
Recruiting
Phase 4
Opioid Free Anesthesia-Analgesia Strategy and Surgical Stress in Elective Open Abdominal Aortic Aneurysm Repair
Opioid UsePostoperative PainAnesthesia+5 more
University of Crete40 enrolled1 locationNCT04894864
Recruiting
Phase 4
Morning Versus Afternoon Administration of Immunotherapy for the Treatment of Advanced or Metastatic Solid Tumors, The Knight SHIFT Study
Metastatic Head and Neck Squamous Cell CarcinomaMetastatic Hepatocellular CarcinomaMetastatic Lung Non-Small Cell Carcinoma+18 more
OHSU Knight Cancer Institute160 enrolled1 locationNCT07405086
Recruiting
Phase 4
Digital Monitoring of Self-reported Symptoms by Patients Treated With Cabozantinib Plus Nivolumab for Advanced Clear-cell Renal Carcinoma
Metastatic Renal Cell CarcinomaLocally AdvancedRenal Cell Carcinoma (Kidney Cancer)
Centre Francois Baclesse83 enrolled16 locationsNCT07028125
Recruiting
Phase 4
Treatment With Aspirin After Preeclampsia: TAP Trial
Cardiovascular DiseasesHypertensionPregnancy Complications+8 more
Malamo Countouris60 enrolled1 locationNCT06281665
Recruiting
Phase 4
Clinical Surveillance vs. Anticoagulation for Low-risk Patients With Isolated Subsegmental Pulmonary Embolism
Cardiovascular DiseasesVenous ThromboembolismPulmonary Embolism+6 more
Drahomir Aujesky276 enrolled40 locationsNCT04263038
Recruiting
Phase 4
Study Aiming to Compare the Plasma Exposure of the Payload (Free-DXd) in Patients Treated by T-DXd for Locally Advanced or Metastatic Breast Cancer According to Their BMI.
Locally Advanced or Metastatic Breast Cancers
Institut Claudius Regaud210 enrolled11 locationsNCT07195344
Recruiting
Phase 4
An Exploratory Study on Efficacy and Safety of Fosaprepitant and Palonosetron Hydrochloride for Injection in Preventing CINV From Multi-Agent HEC
Chemotherapy Induced Nausea and Vomiting
Shanghai 6th People's Hospital200 enrolled1 locationNCT07482891
Not Yet Recruiting
Phase 3Phase 4
Dropless cataract surgery with a single subconjunctival triamcinolone injection versus topical steroid: a randomised controlled trial assessing effects on central macular thickness.
Steroid-induced glaucomaPost operative uveitisCystoid macular oedema
Bayside Health300 enrolled1 locationACTRN12626000516381
Recruiting
Phase 4
Gadopiclenol vs. Gadobutrol for Dynamic Contrast-Enhanced Pituitary MRI (Magnetic Resonance Imaging)
Contrast Enhanced Images vs. Non-contrast ImagesGadopiclinol Enhanced Images vs. Gadobutrol Enhanced Images
UConn Health10 enrolled1 locationNCT06846853
Recruiting
Phase 4
ctDNA-guided Addition of Ipilimumab to Patients Receiving Nivolumab and Relatlimab
Metastatic MelanomaAdvanced Melanoma
NYU Langone Health90 enrolled1 locationNCT07504796
Recruiting
Phase 4
Mechanistic Clinical Trial Comparing the Pharmacokinetics/Pharmacodynamics of Metoprolol in Heart Failure With Reduced Ejection Fraction Patients With Low vs. High Polygenic Score
Heart Failure With Reduced Ejection Fraction
University of Michigan100 enrolled1 locationNCT07490067
Recruiting
Phase 4
Intraperitoneal Infusion of Analgesic for Postoperative Pain Management
Pain, PostoperativeGynecologic Surgical ProceduresHysterectomy+1 more
Ying Liu120 enrolled2 locationsNCT04130464
Recruiting
Phase 4
A Study for the Evaluation of Efficacy and Safety of Prolia® in Participants With Glucocorticoid-induced Osteoporosis in Mainland China
Glucocorticoid-induced Osteoporosis
Amgen100 enrolled16 locationsNCT06588153
Recruiting
Phase 4
RWS of Tunlametinib in NRAS-Mutant Advanced Melanoma
Melanoma Advanced
Fudan University110 enrolled1 locationNCT07445022
Recruiting
Phase 4
Enfortumab Vedotin and Pembrolizumab With Cystectomy and/or Ureterectomy for Locally Advanced or Metastatic Bladder and Upper Urothelial Tract Cancer, CAST-AI Trial
Metastatic Bladder Urothelial CarcinomaStage IV Bladder Cancer AJCC v8Metastatic Renal Pelvis and Ureter Urothelial Carcinoma+4 more
Mayo Clinic75 enrolled1 locationNCT06764095
Recruiting
Phase 4
Vericiguat and Reverse Remodeling Indices in Heart Failure
Heart Failure With Reduced Ejection Fraction (HFrEF)Chronic Heart Failure
University Medical Centre Ljubljana60 enrolled1 locationNCT07405944
Recruiting
Phase 4
Self-Adjusted Nitrous Oxide: A Feasibility Study in the Setting of Vasectomy
Procedural AnxietyProcedural PainPain Catastrophizing
Beth Israel Deaconess Medical Center35 enrolled1 locationNCT05895383
Recruiting
Phase 4
LDA and LMWH vs LDA Alone in High-risk Patients for Preeclampsia Prevention
Pregnancy ComplicationsPreeclampsiaGestational Hypertension+3 more
Alexandra Hospital, Athens, Greece100 enrolled1 locationNCT07361679
Recruiting
Phase 4
Rimegepant as Preemptive Treatment for Predictable Trigger-Induced Migraine in Adult Patients in the US
MigraineTrigger Induced Migraine
Medstar Health Research Institute60 enrolled1 locationNCT07301008
Recruiting
Phase 4
Topical Anesthesia During Catheter Insertion for Cervical Ripening (TOLERANCE)
Labor, Induced
Bnai Zion Medical Center200 enrolled1 locationNCT07288021