Phase 1 Cholangitis Clinical Trials
9 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–9 of 9 trials
Recruiting
Phase 1Phase 2
A Two-part Study to Investigate the Effects in Adults of Two Doses of Golexanolone in Patients With Primary Biliary Cholangitis (PBC) With Fatigue and Cognitive Dysfunction
Primary Biliary Cholangitis (PBC)
Umecrine Cognition AB84 enrolled40 locationsNCT07304843
Recruiting
Phase 1
A Study of TAK-781 in Healthy Volunteers and in Participants With Non-Cirrhotic Primary Sclerosing Cholangitis (PSC)
Healthy VolunteersPrimary Sclerosing Cholangitis
Takeda134 enrolled1 locationNCT07229911
Recruiting
Phase 1
A Study of SIPLIZUMAB in AILD and LT Patients
Autoimmune HepatitisCirrhosis, LiverPrimary Sclerosing Cholangitis+3 more
Elizabeth C. Verna8 enrolled1 locationNCT06455280
Withdrawn
Phase 1
A Phase 1, First-In-Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of PVT201 Following Randomized, Double-blind, Placebo-controlled Single Ascending Doses in primary biliary cholangitis/primary sclerosing cholangitis patients.
Primary Biliary CholangitisPrimary Sclerosing Cholangitis
Parvus Therapeutics, Inc.6 enrolled1 locationACTRN12625000683437
Completed
Phase 1
A Phase 1, First-In-Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of PVT201 Following Randomized, Double-blind, Placebo-controlled Single Ascending Doses in Healthy Subjects.
Primary Biliary Cholangitis
Parvus Therapeutics, Inc.24 enrolled1 locationACTRN12624000967583
Completed
Phase 1
The Relative Oral Bioavailability of a Tablet Formulation vs a Solution of PLN-74809 in Healthy Participants
Primary Sclerosing Cholangitis
Pliant Therapeutics, Inc.24 enrolled1 locationACTRN12620000573954
Completed
Phase 1
Evaluation of the Safety, Tolerability, and Pharmacokinetics of Single and Multiple Ascending Doses of PLN-74809
Primary Sclerosing Cholangitis
Pliant Therapeutics, Inc.80 enrolled1 locationACTRN12620000536965
Completed
Phase 1
Pharmacokinetic and safety study of HTD1801 and its components
Primary Sclerosing Cholangitis (PSC)
Clinical Network Services (CNS) Pty Ltd24 enrolled1 locationACTRN12617000031369
Recruiting
Phase 1
Treating Primary Sclerosing Cholangitis and Biliary Atresia With Vancomycin
Primary Sclerosing CholangitisBiliary Atresia
Sacramento Pediatric Gastroenterology200 enrolled1 locationNCT02137668