Phase 2 Chronic Graft Versus Host Disease Clinical Trials

11 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 111 of 11 trials

Recruiting
Phase 2

A Study of Belumosudil in Children With Chronic Graft Versus Host Disease (schoolROCK)

Chronic Graft Versus Host Disease
Sanofi37 enrolled29 locationsNCT07116031
Recruiting
Phase 2

Belumosudil and Rituximab for Primary Treatment of Chronic Graft-Versus-Host-Disease

Chronic Graft Versus Host Disease
Northside Hospital, Inc.25 enrolled1 locationNCT06046248
Recruiting
Phase 2

Axatilimab for Sclerotic Chronic Graft-versus-Host Disease

Chronic Graft Versus Host Disease
Fred Hutchinson Cancer Center50 enrolled3 locationsNCT07011810
Recruiting
Phase 2

Belumosudil for the Pre-emptive Treatment of Patients With Chronic Graft Versus Host Disease

Chronic Graft Versus Host Disease
Fred Hutchinson Cancer Center82 enrolled4 locationsNCT05996627
Recruiting
Phase 2

BElumosudil for Bronchiolitis Obliterans Prevention/Therapy (BEBOP)

Lung DiseasesBronchiolitis Obliterans SyndromeChronic Graft Versus Host Disease+1 more
Dana-Farber Cancer Institute45 enrolled5 locationsNCT05922761
Recruiting
Phase 2

Ibrutinib for the Prevention of Chronic Graft-Versus-Host Disease in Patients Undergoing Donor Stem Cell Transplant

Hematopoietic and Lymphatic System NeoplasmChronic Graft Versus Host Disease
Mayo Clinic40 enrolled1 locationNCT06271616
Recruiting
Phase 1Phase 2

Gecacitinib for cGVHD: Safety and Efficacy in Patients After ≥2 Lines of Prior Therapy

Chronic Graft Versus Host Disease
Yujun DONG24 enrolled1 locationNCT07012304
Recruiting
Phase 2

Axatilimab in Combination With Extracorporeal Photopheresis (ECP) in Chronic Graft-versus-Host Disease

Chronic Graft Versus Host DiseasecGVHD
University of Miami49 enrolled1 locationNCT06663722
Recruiting
Phase 2

A Clinical Trial of TQ05105 Tablets in the Treatment of Chronic Graft-versus-host Disease

Chronic Graft Versus Host Disease
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.52 enrolled12 locationsNCT06300320
Recruiting
Phase 2

A Phase II Study of the Impact of Two Different Schedules of Thymoglobulin on the Incidence of Extensive Chronic Graft Verus Host Disease (GVHD) in Patients Undergoing Unrelated Donor or Mismatched Related Donor Stem Cell Transplantation

Chronic Graft versus Host Disease in Haematology Malignancy Patients receiving donor stem cell transplantation
The Royal Melbourne Hospital120 enrolled1 locationACTRN12609000173291
Withdrawn
Phase 2

Prospective study of Rituximab for chronic graft vs host disease (GVHD) sub-optimally responsive to immunosuppressive therapy: Assessment of response.

Chronic graft versus host disease post allogeneic bone marrow transplant
Australasian Leukaemia and Lymphoma Group20 enrolled1 locationACTRN12606000326594