Phase 1 Chronic Hepatitis B Infection Clinical Trials
13 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–13 of 13 trials
Recruiting
Phase 1
Single Dose Study to Evaluate the Pharmacokinetics, Safety and Tolerability of Pevifoscorvir Sodium (ALG-000184) in Participants With Renal Impairment and in Healthy Participants With Normal Renal Function
Chronic Hepatitis B Infection
Aligos Therapeutics30 enrolled2 locationsNCT07342881
Recruiting
Phase 1
A Study of SN2001 Dose, Safety & Immunogenicity in Healthy Adults
Chronic Hepatitis B Infection
Chimivac INC36 enrolled1 locationNCT07059403
Not Yet Recruiting
Phase 1
A study to evaluate the safety, tolerability, pharmacokinetics and antiviral activity of BJT-678 in subjects with chronic Hepatitis B Infection, including subjects with Chronic Hepatitis D infection
Chronic Hepatitis D InfectionChronic Hepatitis B Infection
Bluejay Therapeutics, Inc50 enrolled3 locationsACTRN12625000281493
Not Yet Recruiting
Phase 1
A Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy of Cavrotolimod in Subjects with Chronic Hepatitis B Infection
Chronic Hepatitis B Infection
Bluejay Therapeutics, Inc60 enrolled6 locationsACTRN12625000142437
Not Yet Recruiting
Phase 1
A study to evaluate the safety, tolerability, pharmacokinetics and antiviral activity of BJT-678 in Healthy volunteers
Chronic Hepatitis D InfectionChronic Hepatitis B Infection
Bluejay Therapeutics, Inc.80 enrolled1 locationACTRN12624001003561
Not Yet Recruiting
Phase 1
A Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy of Cavrotolimod in Subjects with Chronic Hepatitis B Infection
Chronic Hepatitis B Infection
Bluejay Therapeutics, Inc80 enrolled6 locationsACTRN12624000809538
Recruiting
Phase 1
A Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy of Cavrotolimod in Subjects with Chronic Hepatitis B Infection
Chronic Hepatitis B Infection
Bluejay Therapeutics, Inc40 enrolled6 locationsACTRN12624000808549
Completed
Phase 1
A Multiple Dose Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AB-729 Administered by Subcutaneous Injection to Subjects with Chronic Hepatitis B Infection
Chronic Hepatitis B Infection (CHB)
Arbutus Biopharma Corporation96 enrolled8 locationsACTRN12620000295943
Terminated
Phase 1
A study to evaluate the Safety, Tolerability, and Pharmacokinetics of AB-506 in Healthy Subjects for 28 Days
Chronic Hepatitis B Infection (CHB)
Arbutus Biopharma Corporation28 enrolled1 locationACTRN12619001255178
Completed
Phase 1
A Single Ascending Dose Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AB-729 Administered by Subcutaneous Injection to Subjects with Chronic Hepatitis B Infection
Chronic Hepatitis B Infection (CHB)
Arbutus Biopharma Corporation167 enrolled8 locationsACTRN12619001197123
Completed
Phase 1
A Study to Investigate the Safety, Tolerability and Pharmacokinetics, of AB-729 Administered by Subcutaneous Injection to Healthy Subjects (part 1)
Chronic Hepatitis B Infection
Arbutus Biopharma Corporation24 enrolled1 locationACTRN12619000954123
Completed
Phase 1
A study to investigate the effect of AB-506 on Single Dose Pharmacokinetics of an Oral Contraceptive in Healthy Female Subjects
Chronic Hepatitis B Infection (CHB)
Arbutus Biopharma Corporation32 enrolled1 locationACTRN12619000437167
Recruiting
Phase 1
RO7191863 in patients with chronic hepatitis B
Chronic Hepatitis B Infection
F. Hoffmann-La Roche49 enrolled8 locationsACTRN12619000271101