Phase 1 Chronic Hepatitis Clinical Trials
31 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–20 of 31 trials
Recruiting
Phase 1Phase 2
Study of GS-4321 in Healthy Participants and Participants With Chronic Hepatitis Delta Virus
Chronic Hepatitis Delta
Gilead Sciences107 enrolled15 locationsNCT07096193
Recruiting
Phase 1
A Trial to Evaluate the Efficacy and Safety of WGc0201 in Patients With Chronic Hepatitis B Virus Infection
Chronic Hepatitis B Virus (Hbv)
Jiyan Liu9 enrolled1 locationNCT07051187
Recruiting
Phase 1
A Study on IB-001 Dose Response and Tolerability in Healthy Adults and Those With Chronic Hepatitis B
Chronic Hepatitis B Virus Infection
IntegerBio90 enrolled1 locationNCT07389044
Recruiting
Phase 1
Single Dose Study to Evaluate the Pharmacokinetics, Safety and Tolerability of Pevifoscorvir Sodium (ALG-000184) in Participants With Renal Impairment and in Healthy Participants With Normal Renal Function
Chronic Hepatitis B Infection
Aligos Therapeutics30 enrolled2 locationsNCT07342881
Recruiting
Phase 1
SA1211 Injection Phase 1 Study
Chronic Hepatitis B
Suzhou Siran Biotechnology Co.,Ltd.80 enrolled1 locationNCT07275918
Recruiting
Phase 1
TLR-9 Adjuvanted Vaccination for Chronic Hepatitis B
Hepatitis BChronic Hepatitis B
University of Maryland, Baltimore10 enrolled1 locationNCT04843852
Recruiting
Phase 1
A Study of SN2001 Dose, Safety & Immunogenicity in Healthy Adults
Chronic Hepatitis B Infection
Chimivac INC36 enrolled1 locationNCT07059403
Recruiting
Phase 1
A Heterologous Protein Prime/MVA Boost Therapeutic Hepatitis B Vaccine Candidate
Chronic Hepatitis B
Universitätsklinikum Hamburg-Eppendorf24 enrolled2 locationsNCT05727267
Not Yet Recruiting
Phase 1
A study to evaluate the safety, tolerability, pharmacokinetics and antiviral activity of BJT-678 in subjects with chronic Hepatitis B Infection, including subjects with Chronic Hepatitis D infection
Chronic Hepatitis D InfectionChronic Hepatitis B Infection
Bluejay Therapeutics, Inc50 enrolled3 locationsACTRN12625000281493
Not Yet Recruiting
Phase 1
Safety and Tolerability of CLB-4000 in Subjects with Chronic Hepatitis B: Randomised cohort
Chronic Hepatitis B
ClearB Therapeutics, Inc.8 enrolled1 locationACTRN12625000250437
Not Yet Recruiting
Phase 1
Safety and Tolerability of CLB-4000 in Subjects with Chronic Hepatitis B: non-randomised cohorts
Chronic Hepatitis B
ClearB Therapeutics, Inc.17 enrolled1 locationACTRN12625000204448
Not Yet Recruiting
Phase 1
A Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy of Cavrotolimod in Subjects with Chronic Hepatitis B Infection
Chronic Hepatitis B Infection
Bluejay Therapeutics, Inc60 enrolled6 locationsACTRN12625000142437
Not Yet Recruiting
Phase 1
A study to evaluate the safety, tolerability, pharmacokinetics and antiviral activity of BJT-678 in Healthy volunteers
Chronic Hepatitis D InfectionChronic Hepatitis B Infection
Bluejay Therapeutics, Inc.80 enrolled1 locationACTRN12624001003561
Not Yet Recruiting
Phase 1
A Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy of Cavrotolimod in Subjects with Chronic Hepatitis B Infection
Chronic Hepatitis B Infection
Bluejay Therapeutics, Inc80 enrolled6 locationsACTRN12624000809538
Recruiting
Phase 1
A Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy of Cavrotolimod in Subjects with Chronic Hepatitis B Infection
Chronic Hepatitis B Infection
Bluejay Therapeutics, Inc40 enrolled6 locationsACTRN12624000808549
Completed
Phase 1
A Phase 1, Placebo-controlled, First-in-human Study of Orally Administered DF-006 to Evaluate the Safety, Tolerability, and Pharmacokinetics After Multiple Doses in Chronic Hepatitis B subjects
Chronic Hepatitis B
Zhejiang Yao Yuan Biotechnology Ltd. (Drug Farm)120 enrolled3 locationsACTRN12623000997651
Completed
Phase 1
Study to Evaluate the Safety, Tolerability, Immunogenicity and Antiviral Activity of Multiple Doses of CLB-3000 in participants with Chronic Hepatitis B
Chronic Hepatitis B
ClearB Therapeutics, Inc.12 enrolled8 locationsACTRN12623000841673
Completed
Phase 1
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Antiviral Activity of BJT-778 in Subjects with Chronic HBV Infection (CHB).
Chronic Hepatitis B Virus (HBV) Infection
Bluejay Therapeutics Inc.40 enrolled8 locationsACTRN12623000078651
Completed
Phase 1
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Antiviral Activity of BJT-778 in Healthy Volunteers.
Chronic Hepatitis D Virus (HDV) InfectionChronic Hepatitis B Virus (HBV) Infection
Bluejay Therapeutics Inc32 enrolled1 locationACTRN12623000075684
Completed
Phase 1
A Phase 1, Placebo-controlled, First-in-human Study of Orally Administered DF-006 to Evaluate the Safety, Tolerability, and Pharmacokinetics After a Single Dose and Multiple Doses in Healthy Subjects
Chronic Hepatitis B
Zhejiang Yao Yuan Biotechnology Ltd. (Drug Farm)34 enrolled3 locationsACTRN12621000592842