Chronic Hepatitis Clinical Trials

78 recruitingLast updated: June 17, 2026

There are 78 actively recruiting chronic hepatitis clinical trials across 38 countries. Studies span Phase 2, Phase 1, Not Applicable, Phase 4, Phase 3. Top locations include Beijing, Beijing Municipality, China, Guangzhou, Guangdong, China, Bucharest, Romania. Updated daily from ClinicalTrials.gov.


Chronic Hepatitis Trials at a Glance

78 actively recruiting trials for chronic hepatitis are listed on ClinicalTrialsFinder across 6 cities in 38 countries. The largest study group is Phase 2 with 21 trials, with the heaviest enrollment activity in Beijing, Guangzhou, and Bucharest. Lead sponsors running chronic hepatitis studies include Ausper Biopharma Co., Ltd., Beijing Continent Pharmaceutical Co, Ltd., and Mirum Pharmaceuticals, Inc..

Browse chronic hepatitis trials by phase

Treatments under study

About Chronic Hepatitis Clinical Trials

Looking for clinical trials for Chronic Hepatitis? There are currently 2 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Chronic Hepatitis trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Chronic Hepatitis clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 78 trials

Recruiting
Phase 1Phase 2

TherVacB - A Heterologous Protein Prime/MVA Boost Therapeutic Hepatitis B Vaccine Candidate

Chronic Hepatitis B
Michael Hoelscher81 enrolled6 locationsNCT06513286
Recruiting
Phase 1Phase 2

Study of GS-4321 in Healthy Participants and Participants With Chronic Hepatitis Delta Virus

Chronic Hepatitis Delta
Gilead Sciences200 enrolled19 locationsNCT07096193
Recruiting
Phase 3

A Phase III Study to Evaluate the Efficacy and Safety of Libevitug in Participants With Chronic HDV Infection (D-clear Study)

Chronic Hepatitis D Infection
Huahui Health160 enrolled1 locationNCT07499544
Recruiting
Phase 2

VIR-2218 and Peginterferon Alfa-2a for Chronic Hepatitis B

Chronic Hepatitis B
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)50 enrolled1 locationNCT06092333
Recruiting
Phase 1

A Phase I Clinical Study of AHB - 171 in Healthy Participants(HP) and Chronic Hepatitis B (CHB) Participants

Chronic Hepatitis B Infection
Ausper Biopharma Co., Ltd.110 enrolled1 locationNCT07511218
Recruiting
Not Applicable

Gene Discovery in CHB Patients to Identify Unknown Pathways That Lead to B and NK Cell Deregulation

Chronic Hepatitis B Virus
University Hospital, Limoges140 enrolled3 locationsNCT06853886
Recruiting
Phase 2

A Multicenter Study of AHB-137 Injection Combined With Other Hepatitis B Drugs

Chronic Hepatitis B
Ausper Biopharma Co., Ltd.200 enrolled1 locationNCT07069569
Recruiting

Adaptability of an Undetectable = Untransmissible Model for HBV

Chronic Hepatitis BViremia
NYU Langone Health55 enrolled1 locationNCT07449091
Recruiting
Not Applicable

Assessment of Treatment Adherence and Associated Factors in Chronic HepB Patients Supported by HBVCare

Chronic Hepatitis B
Institute of Gastroenterology and Hepatology, Vietnam70 enrolled2 locationsNCT07540637
Recruiting
Phase 4

ASC22 Combined With Peg-IFNa in Achieving Functional Cure in Patients With Chronic Hepatitis B Virus Infection

Chronic Hepatitis B
The Second Affiliated Hospital of Chongqing Medical University150 enrolled1 locationNCT07573943
Recruiting

Long-term Follow-up Study to Evaluate Participants With Chronic Hepatitis B (CHB) Previously Treated With AHB-137 Injection

Chronic Hepatitis B
Ausper Biopharma Co., Ltd.200 enrolled2 locationsNCT07146100
Recruiting
Phase 2

A Study to Evaluate the Efficacy and Safety of AHB-137 Injection in Participants With Chronic Hepatitis B (CHB)

Chronic Hepatitis B
Ausper Biopharma Co., Ltd.60 enrolled1 locationNCT07137910
Recruiting
Phase 2

A Study Evaluating the Efficacy and Safety of ALG-000184 Compared With Tenofovir Disoproxil Fumarate in Untreated HBeAg-Positive and HBeAg- Negative Adult Subjects With Chronic Hepatitis B (B-SUPREME)

Chronic Hepatitis B Infection
Aligos Therapeutics200 enrolled58 locationsNCT06963710
Recruiting
Phase 2Phase 3

Study to Evaluate Switching to Brelovitug for the Treatment of CHD in Participants Receiving Bulevirtide

Chronic Hepatitis D
Mirum Pharmaceuticals, Inc.120 enrolled22 locationsNCT07454837
Recruiting
Phase 2

A Study of Hydronidone Capsules in Patients With Chronic Hepatitis B Virus-Related Liver Fibrosis

Chronic Hepatitis B-related Liver Fibrosis
Beijing Continent Pharmaceutical Co, Ltd.150 enrolled1 locationNCT07417553
Recruiting
Not Applicable

Fine Needle Aspiration (FNA) Evaluation of the Intrahepatic HBV Reservoir and Its Immunological Characteristics in Chronically HBV-infected Patients

Chronic Hepatitis B
Hospices Civils de Lyon100 enrolled1 locationNCT06047093
Recruiting

Hospital-Based Management of Patients With Chronic Hepatitis B Virus Infection

Chronic Hepatitis B
Third Affiliated Hospital, Sun Yat-Sen University16,300 enrolled3 locationsNCT06966908
Recruiting
Phase 2

Study of Tenofovir Alafenamide (TAF) in Children and Teen Participants With Chronic Hepatitis B Virus Infection

Chronic Hepatitis B
Gilead Sciences150 enrolled62 locationsNCT02932150
Recruiting
Phase 1

A Trial to Evaluate the Efficacy and Safety of WGc0201 in Patients With Chronic Hepatitis B Virus Infection

Chronic Hepatitis B Virus (Hbv)
Jiyan Liu9 enrolled1 locationNCT07051187
Recruiting
Phase 2

A Study to Evaluate the Safety of Hydronidone Capsules in Patients With Liver Fibrosis

Chronic Hepatitis B With Hepatic Fibrosis
Beijing Continent Pharmaceutical Co, Ltd.200 enrolled1 locationNCT07364448