Phase 2 Chronic Myeloid Leukaemia Clinical Trials
7 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–7 of 7 trials
Recruiting
Phase 2
CML14 (ASCENDANCE) - A study to assess efficacy of combination therapy with asciminib plus low dose dasatinib in newly diagnosed chronic phase Chronic Myeloid Leukaemia (CML) with high risk genetics
Chronic Myeloid Leukaemia (CML)
Australasian Leukaemia and Lymphoma Group (ALLG)100 enrolled15 locationsACTRN12623001338651
Recruiting
Phase 2
A multi-centre phase II, Australian and New Zealand, exploratory study of amendments to conditioning regimens in haplo-identical stem cell transplantation
transformed AML/ MDSMyeloproliferative DisordersHodgkin's Disease+4 more
St Vincent's Hospital, Sydney127 enrolled10 locationsACTRN12622001232729
Active
Phase 2
A study for patients with newly diagnosed Chronic Phase Myeloid Leukaemia evaluating the drug Asciminib.
Chronic Myeloid Leukaemia
Australiasian Leukaemia and Lymphoma Group100 enrolled15 locationsACTRN12620000851965
Recruiting
Phase 2
A phase II study of haploidentical peripheral blood stem cell transplantation with post-transplant cyclophosphamide as Graft versus Host Disease (GVHD) prophylaxis
Non Hodgkin's Disease in remissionAcute Myeloid Leukaemia in first or second complete remissionacute Lymphoblastic Leukaemia in first or second complete remission+7 more
St Vincent's Hospital Sydney70 enrolled6 locationsACTRN12617000151336
Completed
Phase 2
A Phase II study in adult patients with newly diagnosed chronic-phase chronic myeloid leukaemia of initial intensified imatinib therapy and sequential dose-escalation followed by treatment with nilotinib in suboptimal responders to determine the rate and duration of major molecular response
newly-diagnosed chronic phase chronic myeloid leukaemia
Australasian Leukaemia and Lymphoma Group150 enrolled1 locationACTRN12607000325404
Completed
Phase 2
A phase II study of withdrawal of imatinib therapy in adult patients with chronic phase chronic myeloid leukaemia in stable molecular remission
Chronic phase chronic myeloid leukaemia in stable molecular remission
Australasian Leukaemia and Lymphoma Group25 enrolled1 locationACTRN12606000118505
Recruiting
Phase 2
Pilot cml autograft/glivec (STI571)/Intron A trial
Advanced phase chronic myeloid leukaemia
Australasian Leukaemia and Lymphoma Group48 enrolled1 locationACTRN12605000071628