Phase 2 Chronic Phase Clinical Trials
12 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–12 of 12 trials
Recruiting
Phase 1Phase 2
Safety and Efficacy of Ponatinib for Treatment of Pediatric Recurrent or Refractory Leukemias, Lymphomas or Solid Tumors
Solid TumorsAcute Lymphoblastic LeukemiaAcute Myeloid Leukemia+6 more
Incyte Biosciences International Sàrl70 enrolled23 locationsNCT03934372
Recruiting
Phase 2
A Study of Treatment-free Remission in Chronic Phase Chronic Myeloid Leukemia
Chronic Myeloid Leukemia, Chronic Phase
Korean Society of Hematology69 enrolled1 locationNCT06368414
Recruiting
Phase 2
Asciminib as Initial Therapy for Patients With Chronic Myeloid Leukemia in Chronic Phase
Leukemia, MyeloidChronic Myeloid Leukemia, Chronic PhaseLeukemia,Myeloid, Chronic+1 more
Augusta University100 enrolled7 locationsNCT05143840
Recruiting
Phase 2
Ponatinib Hydrochloride as Second Line Therapy in Treating Patients With Chronic Myeloid Leukemia in Chronic Phase Resistant or Intolerant to Imatinib Mesylate, Dasatinib, or Nilotinib
Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 PositiveChronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 PositivePhiladelphia Chromosome Positive, BCR-ABL1 Positive Chronic Myelogenous Leukemia
M.D. Anderson Cancer Center50 enrolled1 locationNCT01746836
Recruiting
Phase 2
ASTX727 and Dasatinib for the Treatment of Newly Diagnosed Philadelphia Chromosome or BCR-ABL Positive Chronic Myeloid Leukemia in Chronic Phase
Philadelphia Chromosome PositiveChronic Phase Chronic Myelogenous LeukemiaBCR-ABL1 Positive Chronic Myelogenous Leukemia+1 more
M.D. Anderson Cancer Center70 enrolled1 locationNCT05007873
Recruiting
Phase 1Phase 2
A Phase 1/2 Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of TERN-701 in Participants With Chronic Myeloid Leukemia (CARDINAL)
Chronic Myeloid LeukemiaChronic Myeloid Leukemia, Chronic Phase
Terns, Inc.180 enrolled54 locationsNCT06163430
Recruiting
Phase 2
Personalized NK Cell Therapy in CBT
Acute Lymphoblastic LeukemiaMyelodysplastic SyndromeChronic Myelomonocytic Leukemia+23 more
M.D. Anderson Cancer Center100 enrolled1 locationNCT02727803
Recruiting
Phase 2
Protocol Number: HJKC3-0003. Treatment Free Remission After Asciminib Based Therapy in Chronic Phase Chronic Myeloid Leukemia (CP-CML) Patients Who Relapsed After a Prior Attempt at TKI Discontinuation
Chronic Phase Chronic Myelogenous Leukemia
Medical College of Wisconsin51 enrolled4 locationsNCT04838041
Recruiting
Phase 2
PEARL Study: PotEntial of Asciminib in the eaRly Treatment of CML
Chronic Myeloid LeukemiaChronic Myeloid Leukemia, Chronic PhaseCML, Chronic Phase+1 more
Gruppo Italiano Malattie EMatologiche dell'Adulto160 enrolled11 locationsNCT06409936
Completed
Phase 2
The DIRECT Study: Individualised dasatinib dosing for patients with chronic myelogenous leukaemia.
Chronic Myelogenous Leukaemia in Chronic Phase
Australasian Leukaemia and Lymphoma Group80 enrolled13 locationsACTRN12616000738426
Completed
Phase 2
A Phase II study in adult patients with newly diagnosed chronic-phase chronic myeloid leukaemia of initial intensified imatinib therapy and sequential dose-escalation followed by treatment with nilotinib in suboptimal responders to determine the rate and duration of major molecular response
newly-diagnosed chronic phase chronic myeloid leukaemia
Australasian Leukaemia and Lymphoma Group150 enrolled1 locationACTRN12607000325404
Completed
Phase 2
A phase II study of withdrawal of imatinib therapy in adult patients with chronic phase chronic myeloid leukaemia in stable molecular remission
Chronic phase chronic myeloid leukaemia in stable molecular remission
Australasian Leukaemia and Lymphoma Group25 enrolled1 locationACTRN12606000118505