Phase 4 CLE Clinical Trials
73 recruitingPhase 4
What is a Phase 4 trial?
Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.
Showing 1–20 of 73 trials
Recruiting
Phase 4
Cilostazol and Aspirin for Cardiovascular Event Prevention in Patients With Type 2 Diabetes
AtherosclerosisType 2 Diabetes Mellitus (T2DM)
Seoul National University Bundang Hospital1,200 enrolled1 locationNCT07719894
Recruiting
Phase 4
Safety and Immunogenicity of the Live Attenuated Tetravalent Butantan-Dengue Vaccine in Autoimmune Rheumatic Diseases
Psoriatic Arthritis (PsA)Rheumatoid Arthritis (RA)Systemic Lupus Erythematosus (SLE)+9 more
University of Sao Paulo General Hospital477 enrolled2 locationsNCT07087912
Recruiting
Phase 4
Precision Colchicine Intervention to Suppress Atherosclerosis in TET2 Clonal Hematopoiesis
Clonal Hematopoiesis of Indeterminate PotentialColchicineCoronary Atherosclerosis Management
Shenyang Northern Hospital120 enrolled1 locationNCT07362966
Recruiting
Phase 4
Safety and Efficacy Study of Fingolimod in Taiwanese Adults (≥ 20years) With Relapsing Remitting Multiple Sclerosis
Multiple Sclerosis
Novartis Pharmaceuticals30 enrolled6 locationsNCT04480853
Recruiting
Phase 4
Ocrelizumab Discontinuation in Relapsing Multiple Sclerosis
Multiple Sclerosis
National Institute of Allergy and Infectious Diseases (NIAID)123 enrolled13 locationsNCT05285891
Recruiting
Phase 4
PRP vs PRP+Betamethasone vs Betamethasone Injection for Upper Trapezius Myofascial Pain
Trigger Point in Trapezius MuscleMyofascial Pain Dysfunction SyndromeTrigger Points, Myofascial
University of Kyrenia150 enrolled2 locationsNCT07547605
Recruiting
Phase 4
PCSK9 Inhibitor With Statin Therapy for Asymptomatic Intracranial Atherosclerosis
Atherosclerotic PlaqueIntracranial AtherosclerosisIntracranial Artery Stenosis
Peking Union Medical College Hospital300 enrolled19 locationsNCT06902740
Recruiting
Phase 4
Pediatric Long-Term Follow-up and Rollover Study
Neurofibromatosis Type 1GlioblastomaAnaplastic Astrocytoma+20 more
Novartis Pharmaceuticals165 enrolled55 locationsNCT03975829
Recruiting
Phase 4
Intravascular Imaging Study of the Effect of Inclisiran on Plaque in Patients With Acute Myocardial Infarction
Plaque, Atherosclerotic
Novartis Pharmaceuticals318 enrolled20 locationsNCT06372925
Recruiting
Phase 4
Dual PCSK9 Inhibition With Inclisiran and Alirocumab in Secondary Prevention
Atherosclerotic Cardiovascular Disease (ASCVD)Hypercholesterolemia
University Medical Centre Ljubljana60 enrolled1 locationNCT07581808
Recruiting
Phase 4
Silodosin for Urinary Symptoms in Female Patients With Multiple Sclerosis
Multiple SclerosisLower Urinary Track Symptoms
Atlantic Health System60 enrolled1 locationNCT07614321
Recruiting
Phase 4
SGLT2 Inhibitors on Coronary Atherosclerosis Progression Via Perivascular Adipose Tissue in Diabetes
AtherosclerosisType 2 Diabetes Mellitus (T2DM)Coronary Artery Disease
Junjie Yang144 enrolled2 locationsNCT07614230
Recruiting
Phase 4
A Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Ocrelizumab in Participants With Relapsing Multiple Sclerosis and Primary Progressive Multiple Sclerosis
Relapsing Multiple SclerosisPrimary Progressive Multiple Sclerosis
Hoffmann-La Roche60 enrolled17 locationsNCT07483450
Recruiting
Phase 4
Carotid Ultrasound-Based Strategy for Primary Prevention of Cardiovascular Events in Inflammatory Rheumatic Disease (PREVENER)
Psoriatic Arthritis (PsA)AtherosclerosisRheumatoid Arthritis (RA)+4 more
Instituto de Investigación Marqués de Valdecilla1,944 enrolled17 locationsNCT07611747
Recruiting
Phase 4
ELIOS - Investigational Biomarkers to Track Disease Modification in Active RRMS
Relapsing-remitting Multiple Sclerosis (RRMS)
Novartis Pharmaceuticals224 enrolled14 locationsNCT06733922
Recruiting
Phase 4
Choline Fenofibrate and Carotid Atherosclerosis in Patients With Type 2 Diabetes and Combined Dyslipidemia
Diabetes Mellitus, Type 2AtherosclerosisDyslipidemia
Seoul National University Bundang Hospital56 enrolled1 locationNCT05365425
Recruiting
Phase 4
Atmeg (Atorvastatin and Omega-3 Combination) and Carotid Atherosclerosis in Patients With Type 2 Diabetes and Combined Dyslipidemia
Diabetes Mellitus, Type 2AtherosclerosisDyslipidemias
Seoul National University Bundang Hospital105 enrolled1 locationNCT05365438
Recruiting
Phase 4
Clopidogrel Versus Cilostazol on Vessels
AtherosclerosisType 2 Diabetes
Seoul National University Bundang Hospital120 enrolled1 locationNCT06402747
Recruiting
Phase 4
Study of Ublituximab for Ocrelizumab Wearing-Off in Multiple Sclerosis
Multiple Sclerosis
Johns Hopkins University50 enrolled1 locationNCT07389590
Recruiting
Phase 4
Study to Evaluate the Impact of a Targeted Lipid Optimization Program on LDL-C Control in At-risk Adult Patients With Dyslipidemia
Atherosclerotic Cardiovascular Disease
Novartis Pharmaceuticals326 enrolled1 locationNCT07034690