Phase 4 CLE Clinical Trials

67 recruitingPhase 4

What is a Phase 4 trial?

Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.

Showing 120 of 67 trials

Recruiting
Phase 4

ELIOS - Investigational Biomarkers to Track Disease Modification in Active RRMS

Relapsing-remitting Multiple Sclerosis (RRMS)
Novartis Pharmaceuticals224 enrolled14 locationsNCT06733922
Recruiting
Phase 4

Pediatric Long-Term Follow-up and Rollover Study

Neurofibromatosis Type 1GlioblastomaAnaplastic Astrocytoma+20 more
Novartis Pharmaceuticals165 enrolled55 locationsNCT03975829
Recruiting
Phase 4

Clopidogrel Versus Cilostazol on Vessels

AtherosclerosisType 2 Diabetes
Seoul National University Bundang Hospital120 enrolled1 locationNCT06402747
Recruiting
Phase 4

Choline Fenofibrate and Carotid Atherosclerosis in Patients With Type 2 Diabetes and Combined Dyslipidemia

Diabetes Mellitus, Type 2AtherosclerosisDyslipidemia
Seoul National University Bundang Hospital56 enrolled1 locationNCT05365425
Recruiting
Phase 4

Atmeg (Atorvastatin and Omega-3 Combination) and Carotid Atherosclerosis in Patients With Type 2 Diabetes and Combined Dyslipidemia

Diabetes Mellitus, Type 2AtherosclerosisDyslipidemias
Seoul National University Bundang Hospital105 enrolled1 locationNCT05365438
Recruiting
Phase 4

Study of Ublituximab for Ocrelizumab Wearing-Off in Multiple Sclerosis

Multiple Sclerosis
Johns Hopkins University50 enrolled1 locationNCT07389590
Recruiting
Phase 4

Study to Evaluate the Impact of a Targeted Lipid Optimization Program on LDL-C Control in At-risk Adult Patients With Dyslipidemia

Atherosclerotic Cardiovascular Disease
Novartis Pharmaceuticals326 enrolled1 locationNCT07034690
Recruiting
Phase 4

A Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Ocrelizumab in Participants With Relapsing Multiple Sclerosis and Primary Progressive Multiple Sclerosis

Relapsing Multiple SclerosisPrimary Progressive Multiple Sclerosis
Hoffmann-La Roche60 enrolled17 locationsNCT07483450
Recruiting
Phase 4

The Effect of InTensive Statin in Ischemic Stroke With inTracranial Atherosclerotic Plaques

Stroke, IschemicAtherosclerosis, Cerebral
General Hospital of Shenyang Military Region100 enrolled1 locationNCT03753555
Recruiting
Phase 4

Ocrelizumab Discontinuation in Relapsing Multiple Sclerosis

Multiple Sclerosis
National Institute of Allergy and Infectious Diseases (NIAID)123 enrolled12 locationsNCT05285891
Recruiting
Phase 4

BoTox Into the Sternocleidomastoid Muscles (SCM)

Neck Muscle Issue
Boston Medical Center30 enrolled1 locationNCT06903975
Recruiting
Phase 4

Safety and Immunogenicity of the Live Attenuated Tetravalent Butantan-Dengue Vaccine in Autoimmune Rheumatic Diseases

Psoriatic Arthritis (PsA)Rheumatoid Arthritis (RA)Systemic Lupus Erythematosus (SLE)+9 more
University of Sao Paulo General Hospital477 enrolled2 locationsNCT07087912
Recruiting
Phase 4

Optimizing Perioperative Analgesia to Lower Pain Following Cleft Palate Surgery

PainCleft PalatePerioperative Care+2 more
Duke University60 enrolled1 locationNCT06962306
Recruiting
Phase 4

Intravascular Imaging Study of the Effect of Inclisiran on Plaque in Patients With Acute Myocardial Infarction

Plaque, Atherosclerotic
Novartis Pharmaceuticals334 enrolled20 locationsNCT06372925
Recruiting
Phase 4

Safety and Efficacy Study of Fingolimod in Taiwanese Adults (≥ 20years) With Relapsing Remitting Multiple Sclerosis

Multiple Sclerosis
Novartis Pharmaceuticals30 enrolled6 locationsNCT04480853
Recruiting
Phase 4

A Study to Continue the Administration of Deucravacitinib in Participants With Systemic Lupus Erythematosus (SLE) or Discoid and/or Subacute Cutaneous Lupus Erythematosus (DLE/SCLE) Who Have Completed Study IM011074 or Study IM011132

Systemic Lupus Erythematosus (SLE)Discoid and/or Subacute Cutaneous Lupus Erythematosus (DLE/SCLE)
Bristol-Myers Squibb35 enrolled4 locationsNCT06875960
Recruiting
Phase 4

Ublituximab (Briumvi) for Early Forms of Relapsing Multiple Sclerosis

Multiple SclerosisMultiple Sclerosis (MS) - Relapsing-remitting
Northwestern University40 enrolled1 locationNCT07225361
Recruiting
Phase 4

Studying the Relationship of Patient Positioning and Intravesical Bacillus Calmette Guerin Dwell Time to Improve the Treatment of Non-muscle Invasive Bladder Cancer

Non-Muscle Invasive Bladder Carcinoma
Ohio State University Comprehensive Cancer Center40 enrolled1 locationNCT07474519
Recruiting
Phase 4

Pharmacokinetic Analysis of Cefiderocol in Patients With Acute Burn Injuries

Drug Clearance After Severe Burn Injury
University of Tennessee12 enrolled1 locationNCT07465432
Recruiting
Phase 4

Sparsentan in Posttransplant Immunoglobulin A Nephropathy or Focal Segmental Glomerulosclerosis

Kidney TransplantFocal Segmental GlomerulosclerosisProteinuria+1 more
Travere Therapeutics, Inc.20 enrolled9 locationsNCT07219121