Phase 3 Clinical Clinical Trials

13 recruitingPhase 3

What is a Phase 3 trial?

Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.

Showing 113 of 13 trials

Recruiting
Phase 2Phase 3

Adding Nivolumab to Usual Treatment for People With Advanced Stomach or Esophageal Cancer, PARAMUNE Trial

Clinical Stage III Gastric Cancer AJCC v8Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8Clinical Stage IV Gastric Cancer AJCC v8+13 more
National Cancer Institute (NCI)224 enrolled371 locationsNCT06203600
Recruiting
Phase 3

mFOLFIRINOX Versus mFOLFOX With or Without Nivolumab for the Treatment of Advanced, Unresectable, or Metastatic HER2 Negative Esophageal, Gastroesophageal Junction, and Gastric Adenocarcinoma

Clinical Stage III Gastric Cancer AJCC v8Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8Clinical Stage IV Gastric Cancer AJCC v8+12 more
Alliance for Clinical Trials in Oncology382 enrolled792 locationsNCT05677490
Recruiting
Phase 3

Comparing Proton Therapy to Photon Radiation Therapy for Esophageal Cancer

Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8Clinical Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8Clinical Stage II Esophageal Squamous Cell Carcinoma AJCC v8+10 more
NRG Oncology300 enrolled95 locationsNCT03801876
Recruiting
Phase 3

A Study to Investigate Bowel Cleansing With PLENVU® Compared to Sodium Picosulfate in Participants Aged 1 to < 18 Years of Age in Preparation for Colonoscopy

Bowel Cleansing Prior to Clinical Procedures
Norgine212 enrolled40 locationsNCT07218523
Recruiting
Phase 3

CAR-T Long Term Follow Up (LTFU) Study

Long Term Safety of Patients Receiving CAR-T in an Eligible Clinical Trial or Managed Access Program
Novartis Pharmaceuticals1,400 enrolled118 locationsNCT02445222
Recruiting
Phase 3

Decreasing Risk of Psychosis by Sulforaphane (DROPS Trial)

Clinical High-risk Syndrome of Psychosis
Shanghai Jiao Tong University School of Medicine300 enrolled9 locationsNCT03932136
Recruiting
Phase 3

VAsopressin and STeroids in Addition to Adrenaline in Cardiac Arrest - a Randomized Clinical Trial

Cardiac Arrest;In-hospital Cardiac Arrest; Methylprednisolone; Vasopressin; Adrenaline; Randomized Clinical Trial
Tiohundra AB1,276 enrolled2 locationsNCT05139849
Completed
Phase 3Phase 4

low level laser and osteoarthritis

aim of this randomized placebo-controlled single-blind clinical trial was to evaluate the short-term efficacy of LLLT on pain alleviation and functional performance in the patients with chronic knee OA
Mohammed taher ahmed omar42 enrolled1 locationACTRN12612000615886
Completed
Phase 2Phase 3

Clinical trial of a Chinese herbal medicine for the treatment of prediabetes and mild diabetes

Mild diabetes defined as those with diabetes diagnosed within 5 yrs of enrolment in the clinical trial, diet and exercise controlled and not taking any medications.Impaired glucose tolerance defined as having a fasting blood glucose <7.8 mmol and a 2 hour post prandial blood glucose >7.8 but <11.00
Xiyuan Hospital100 enrolled1 locationACTRN12612000128897
Recruiting
Phase 3

Evaluating the Utility of a Patient Decision Aid for Prospective Participants in the Trans-Tasman Radiation Oncology Group Radiotherapy - Adjuvant Versus Early Salvage Prostate Cancer Trial

Decision-making for clinical trial participation in men with prostate cancer who have positive margins and/or pathologic stage T3 (pT3; cancer extending beyond the capsule of the prostate gland) disease following radical prostatectomy, aged over 18 years.
Psycho-Oncology Cooperative Research Group (PoCoG)150 enrolled2 locationsACTRN12611001024932
Not Yet Recruiting
Phase 3

Study for the assessment of clinical non-inferiority and tolerability of Estrogenon (Sanval Comercio e Industria Ltda) in comparasion to Premarin (Wyeth Industria Farmaceutica Ltda) in women post menopause.

Study with the purpose of check clinical non- inferiority and tolerance of conjugated estrogen coated tablet manufactured by different manufacturesWomen in post menopause with indications for estrogens replacement therapy.
Sanval Comercio e Industria Ltda66 enrolled1 locationACTRN12610000119099
Not Yet Recruiting
Phase 3

Study for the assessment of clinical non-inferiority and tolerability of different conjugated estrogen vaginal cream ESTROGENON (Sanval Comercio e Industria Ltda) versus PREMARIN (Wyeth Industria Farmaceutica Ltda) in women post menopause.

Women in post menopause with indications for estrogen replacement therapy.Study with the purpose of check clinical non-inferiority and tolerance of two vaginal cream based on the conjugated estrogen manufactured by different manufacturers.
Sanval Comercio e Industria Ltda.66 enrolled1 locationACTRN12610000103066
Completed
Phase 3

A Randomised, controlled trial of mask use in control of respiratory virus transmission in Health Care Workers

Respiratory infections (clinical case definition)Respiratory infections (laboratory confirmed)
The Children's Hospital at Westmead500 enrolled1 locationACTRN12607000314426