Phase 2 Colorectal Adenocarcinoma Clinical Trials
10 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–10 of 10 trials
Recruiting
Phase 1Phase 2
A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression
Colorectal, CancerOvarian CancerLung Cancer+17 more
A2 Biotherapeutics Inc.474 enrolled12 locationsNCT06051695
Recruiting
Phase 1Phase 2
Testing the Effectiveness of the Anti-cancer Drug Pidnarulex (CX-5461), in Combination With Another Anti-cancer Drug Cemiplimab (REGN2810), in Treating Refractory Microsatellite Stable Colorectal Cancer
Stage IV Colorectal Cancer AJCC v8Stage III Colorectal Cancer AJCC v8Metastatic Colorectal Adenocarcinoma+2 more
National Cancer Institute (NCI)86 enrolled1 locationNCT07147231
Recruiting
Phase 1Phase 2
Dual-Targeting CAR-NK Cells in Biomarker-Selected Advanced Colorectal Cancer
Colorectal, CancerMetastatic Colorectal AdenocarcinomaUnresectable Colorectal Cancer
Beijing Biotech48 enrolled1 locationNCT07589517
Recruiting
Phase 1Phase 2
A Study of VS-6766 and Cetuximab in Patients With Advanced Colorectal Cancer
Colorectal, CancerAdvanced Colorectal CarcinomaAdvanced Colorectal Adenocarcinoma+2 more
University of Chicago53 enrolled1 locationNCT05200442
Recruiting
Phase 2
Upfront Trastuzumab-Deruxtecan Plus Capecitabine and Bevacizumab for Patients With HER-2 Positive Metastatic Colorectal Cancer.
Colorectal, CancerRectal AdenocarcinomaColorectal Adenocarcinoma+4 more
Gruppo Oncologico del Nord-Ovest42 enrolled28 locationsNCT07407465
Recruiting
Phase 2
Amplitude-Modulated Radiofrequency Electromagnetic Fields (AM RF EMF) in Combination With Fruquintinib in Refractory Metastatic Colorectal Cancer
Metastatic Colorectal Adenocarcinoma
Barbara Ann Karmanos Cancer Institute102 enrolled9 locationsNCT07130903
Recruiting
Phase 2
Pembrolizumab and Odetiglucan in Liver Predominant Metastatic Colorectal Adenocarcinoma
Colorectal Adenocarcinoma Metastatic in the Liver
Abramson Cancer Center at Penn Medicine27 enrolled1 locationNCT07082439
Recruiting
Phase 1Phase 2
A Study to Evaluate the Safety and Efficacy of A2B395, an Allogeneic Logic-gated CAR T, in Participants With Solid Tumors That Express EGFR and Have Lost HLA-A*02 Expression
Triple-Negative Breast CancerColorectal, CancerLung Cancer+14 more
A2 Biotherapeutics Inc.240 enrolled10 locationsNCT06682793
Recruiting
Phase 1Phase 2
AK129 Combination Therapy for Advanced Solid Tumors
Head and Neck Squamous Cell Carcinoma (HNSCC)Advanced Solid TumorsColorectal Adenocarcinoma+1 more
Akeso230 enrolled1 locationNCT06943820
Recruiting
Phase 2
Encorafenib + Cetuximab Beyond Progression in Combination With FOLFIRI in Patients With BRAF V600E Mutated Metastatic Colorectal Cancer Progressing on Encorafenib + Cetuximab.
Colorectal, CancerColorectal CarcinomaColon Cancer+7 more
Fondazione Policlinico Universitario Agostino Gemelli IRCCS25 enrolled3 locationsNCT06640166