Phase 2 coma Clinical Trials
240 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 240 trials
Recruiting
Phase 2
Assessment of the Long-term Efficacy of Moderately Hypofractionated Neoadjuvant Radiotherapy Soft Tissue Sarcoma in the Limbs or Trunk Wall
Soft Tissue Sarcoma AdultSoft Tissue Sarcoma (Excluding GIST)Soft Tissue Sarcoma of the Trunk and Extremities+1 more
Centre Oscar Lambret135 enrolled1 locationNCT07507773
Recruiting
Phase 2Phase 3
A Study to Test the Addition of the Drug Cabozantinib to Chemotherapy in Patients With Newly Diagnosed Osteosarcoma
Metastatic OsteosarcomaHigh Grade OsteosarcomaLocalized Osteosarcoma+1 more
National Cancer Institute (NCI)1,122 enrolled202 locationsNCT05691478
Recruiting
Phase 2
Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors
Stage IV Renal Cell Cancer AJCC v8Stage IVB Prostate Cancer AJCC v8Large Cell Neuroendocrine Carcinoma+42 more
National Cancer Institute (NCI)314 enrolled582 locationsNCT03866382
Recruiting
Phase 2
Testing Atezolizumab With Selinexor in People ≥ 12 Years Old With Alveolar Soft Part Sarcoma, AXIOM Trial
Metastatic Alveolar Soft Part SarcomaAdvanced Soft Tissue SarcomaAdvanced Alveolar Soft Part Sarcoma+2 more
National Cancer Institute (NCI)27 enrolled13 locationsNCT05333458
Recruiting
Phase 2
Metformin Hydrochloride in Combination With Standard of Care Systemic Therapy in Previously Untreated Advanced Unresectable or Metastatic Soft Tissue Sarcoma
Sarcoma,Soft TissueSarcoma Metastatic
Wake Forest University Health Sciences50 enrolled2 locationsNCT07291297
Recruiting
Phase 1Phase 2
Domatinostat With Sirolimus for Relapsed, Refractory Sarcoma and Osteosarcoma
SarcomaOsteosarcoma
H. Lee Moffitt Cancer Center and Research Institute74 enrolled4 locationsNCT07725380
Recruiting
Phase 1Phase 2
PEEL-224, Vincristine and Temozolomide in Pediatric Solid Tumors
Refractory NeuroblastomaRefractory RhabdomyosarcomaRefractory Solid Tumors+3 more
Theodore Laetsch59 enrolled7 locationsNCT06721689
Recruiting
Phase 1Phase 2
PDS01ADC Monotherapy and in Combination With M7824 in Advanced Kaposi Sarcoma
Kaposi Sarcoma
National Cancer Institute (NCI)80 enrolled1 locationNCT04303117
Recruiting
Phase 1Phase 2
STC-15 as a Part of Combination Therapy With Toripalimab in Selected Advanced Cancers and as Monotherapy in Participants With Selected Sarcomas
SarcomaSolid TumorLeiomyosarcoma+1 more
STORM Therapeutics LTD107 enrolled9 locationsNCT06975293
Recruiting
Phase 1Phase 2
Trastuzumab Deruxtecan (DS-8201a) for the Treatment of Recurrent or Refractory Osteosarcoma, Wilms Tumor, and Desmoplastic Small Round Cell Tumor
OsteosarcomaRecurrent OsteosarcomaWilms Tumor+5 more
National Cancer Institute (NCI)55 enrolled28 locationsNCT04616560
Recruiting
Phase 1Phase 2
Trial of Single Protein Encapsulated Doxorubicin, SPEDOX-6 in Advanced Malignancies
Triple-Negative Breast CancerOvarian CancerCervical Cancer+3 more
University of California, Irvine67 enrolled1 locationNCT07064018
Recruiting
Phase 1Phase 2
A Study Evaluating the Efficacy and Safety of Risvutatug Rezetecan in Participants With Advanced Sarcomas (EMBOLD Sarcoma-202)
Sarcoma
GlaxoSmithKline113 enrolled6 locationsNCT07602777
Recruiting
Phase 2
Repurposing Riluzole for Cancer-Related Cognitive Impairment: A Pilot Trial
Breast CancerLiver CancerColorectal, Cancer+19 more
University of California, Irvine75 enrolled1 locationNCT06580002
Recruiting
Phase 1Phase 2
Atezolizumab Plus Tivozanib in Immunologically Cold Tumor Types
Breast CancerOvarian CancerProstate Cancer+6 more
University of Florida29 enrolled1 locationNCT05000294
Recruiting
Phase 2
Eflornithine (DFMO) for Ewing Sarcoma and Osteosarcoma
OsteosarcomaEwing Sarcoma
Milton S. Hershey Medical Center406 enrolled2 locationsNCT07321912
Recruiting
Phase 1Phase 2
Proton-Spatially Fractionated Radiotherapy and Standard Radiation Therapy for the Treatment of Newly Diagnosed Retroperitoneal Soft Tissue Sarcoma
Retroperitoneal Sarcoma
Northwestern University28 enrolled1 locationNCT06327477
Recruiting
Phase 1Phase 2
Lead-212 PSV359 Therapy for Patients With Solid Tumors
Colorectal, CancerEsophageal CancerGastric Cancer+5 more
Perspective Therapeutics112 enrolled11 locationsNCT06710756
Recruiting
Phase 2
Single-site Pilot Study Evaluating the Effect of QLS-111 Ophthalmic Solution on Posterior Perfusion and Vessel Dilation
Normal Tension Glaucoma (NTG)Non-proliferative Diabetic Retinopathy (NPDR)Open-angle Glaucoma (OAG)
Qlaris Bio, Inc.14 enrolled1 locationNCT07354477
Recruiting
Phase 1Phase 2
NRSTS2021, A Risk Adapted Study Evaluating Maintenance Pazopanib, Limited Margin, Dose-Escalated Radiation Therapy and Selinexor in Non-Rhabdomyosarcoma Soft Tissue Sarcoma (NRSTS)
AngiosarcomaLiposarcomaAdipocytic Neoplasm+6 more
St. Jude Children's Research Hospital139 enrolled7 locationsNCT06239272
Recruiting
Phase 2
Testing the Addition of Immunotherapy Before Surgery for Patients With Sarcomatoid Mesothelioma
Pleural Biphasic MesotheliomaPleural Sarcomatoid Mesothelioma
Alliance for Clinical Trials in Oncology26 enrolled132 locationsNCT05647265