First-in-Human Study of ADCE-D01 in Soft Tissue Sarcoma

This is a first-in-human study of a new investigational drug called ADCE-D01 in patients with soft tissue sarcoma (a rare type of cancer affecting muscles, fat, nerves, or connective tissue) that has spread or cannot be removed by surgery. The study will assess how safe the drug is and how well the body handles it. **You may be eligible if...** - You are 18 or older - You have a confirmed diagnosis of soft tissue sarcoma that has spread or cannot be surgically removed - You have received 1 or 2 previous lines of chemotherapy for your disease - Your cancer is measurable on imaging - You are in reasonably good health (ECOG 0-1) and have a life expectancy of at least 3 months - You are willing to use contraception during and after the study **You may NOT be eligible if...** - You have received more than 2 prior systemic treatments for metastatic/unresectable disease - You have poor organ function or significant other medical conditions - You are pregnant or breastfeeding Talk to your doctor to see if this trial is right for you.