Common Variable Immunodeficiency Clinical Trials

6 recruiting

Common Variable Immunodeficiency Trials at a Glance

7 actively recruiting trials for common variable immunodeficiency are listed on ClinicalTrialsFinder across 6 cities in 2 countries. The largest study group is Phase 2 with 4 trials, with the heaviest enrollment activity in Bethesda, Birmingham, and Burlington. Lead sponsors running common variable immunodeficiency studies include National Cancer Institute (NCI), Children's Hospital Medical Center, Cincinnati, and National Heart, Lung, and Blood Institute (NHLBI).

Browse common variable immunodeficiency trials by phase

Treatments under study

About Common Variable Immunodeficiency Clinical Trials

Looking for clinical trials for Common Variable Immunodeficiency? There are currently 6 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Common Variable Immunodeficiency trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Common Variable Immunodeficiency clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 17 of 7 trials

Recruiting
Phase 2

Pilot Trial of Allogeneic Blood or Marrow Transplantation for Primary Immunodeficiencies

Lymphoproliferative DisordersImmune System DiseasesCommon Variable Immunodeficiency+2 more
National Cancer Institute (NCI)354 enrolled2 locationsNCT02579967
Recruiting

Natural History of Bronchiectasis

Cystic FibrosisBronchiectasisAutoimmune Disease+1 more
National Heart, Lung, and Blood Institute (NHLBI)900 enrolled1 locationNCT00943514
Recruiting
Phase 2

Hematopoietic Stem Cell Transplantation (HSCT) for Common Variable Immunodeficiency (CVID) and Other Autoimmune Manifestations of Primary Immune Regulatory Disorders (PIRD)

Immune DysregulationPrimary Immune Regulatory DisorderCommon Variable Immunodeficiency (CVID)+4 more
Paul Szabolcs25 enrolled1 locationNCT07284641
Recruiting
Phase 2

Abatacept for the Treatment of Common Variable Immunodeficiency With Interstitial Lung Disease

Interstitial Lung DiseaseCommon Variable Immunodeficiency
Children's Hospital Medical Center, Cincinnati38 enrolled6 locationsNCT04925375
Recruiting
Phase 2

Allogeneic Hematopoietic Stem Cell Transplant for Patients With Inborn Errors of Immunity

Lymphoproliferative DisordersImmune System DiseasesCommon Variable Immunodeficiency+2 more
National Cancer Institute (NCI)66 enrolled1 locationNCT04339777
Recruiting
Phase 4

Usage of Spirometry in Managing IgG Therapy in CVID with Airway Disease

Common Variable Immunodeficiency
University of Alabama at Birmingham22 enrolled1 locationNCT05193552
Recruiting

Prediction of Portal Hypertension in Patients With CVID (CVID-pHT)

Non-Cirrhotic Portal HypertensionCommon Variable Immunodeficiency
University Hospital Freiburg250 enrolled1 locationNCT06145100