Phase 1 Cornea Clinical Trials
10 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–10 of 10 trials
Recruiting
Phase 1
Study to Evaluate the Safety and Efficacy of CSB-001 Ophthalmic Solution 0.1% in Subjects With Corneal Scars
Corneal Scar
Claris Biotherapeutics, Inc.20 enrolled7 locationsNCT06257355
Recruiting
Phase 1
PVEK Corneal Implant For Treatment of Corneal Edema
Pseudophakic Bullous KeratopathyFuchs' Endothelial DystrophyCorneal Edema+1 more
Precise Bio15 enrolled3 locationsNCT07325097
Recruiting
Phase 1Phase 2
Clinical Study of Intrastromal Anti-VEGF Injection for Corneal Neovascularization.
Herpes Simplex KeratitisCorneal Neovascularization
Second Affiliated Hospital, School of Medicine, Zhejiang University100 enrolled1 locationNCT07329686
Recruiting
Phase 1
Study to Assess Safety and Tolerability of Multiple Doses of EO2002
Endothelial DysfunctionPseudophakic Bullous KeratopathyFuchs' Endothelial Dystrophy+5 more
Asociación para Evitar la Ceguera en México12 enrolled1 locationNCT05636579
Recruiting
Phase 1
Safety and Tolerability of EO2002
Endothelial Cell Loss, CornealCataract
Asociación para Evitar la Ceguera en México32 enrolled1 locationNCT05587205
Recruiting
Phase 1
Safety and Efficacy of Tissue Engineered Endothelial Keratoplasty
Fuchs' Endothelial DystrophyBullous KeratopathyMild to Moderate Corneal Endothelial Decompensation+1 more
Singapore Eye Research Institute30 enrolled1 locationNCT04319848
Recruiting
Phase 1
Safety and Effectiveness of the PXL-Platinum 330 System for Corneal Cross-Linking
Bacterial KeratitisEctasia of CorneaKeratoconus, Unstable
Pacific Clear Vision Institute300 enrolled1 locationNCT03918408
Recruiting
Phase 1
Topical Infliximab for Sterile Corneal Melt
Sterile Corneal Melt
Centre hospitalier de l'Université de Montréal (CHUM)12 enrolled1 locationNCT02987686
Recruiting
Phase 1Phase 2
A Study to Investigate Safety and Clinical Activity of Belantamab Mafodotin in Combination With Lenalidomide, Dexamethasone and Nirogacestat in Patients With Transplant Ineligible Newly Diagnosed Multiple Myeloma
NeoplasmsMultiple MyelomaParaproteinemias+5 more
Hellenic Society of Hematology36 enrolled2 locationsNCT05573802
Withdrawn
Phase 1
Evaluation of the Safety and Efficacy of CMB-012 in Subjects with Chemical Burns of the Cornea and/or Persistent Corneal Epithelial Defects (PCED)
Chemical BurnPersistent Corneal Epithelial Defect
Combangio, Inc.6 enrolled1 locationACTRN12619001724167