Cornea Clinical Trials

4 recruiting

Frequently Asked Questions

Common questions about Cornea clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 71 trials

Recruiting
Not Applicable

The Belgian Endothelial Surgical Transplant of the Cornea

Pseudophakic Bullous KeratopathyFuchs' Endothelial DystrophyCorneal Edema+2 more
University Hospital, Antwerp220 enrolled11 locationsNCT05436665
Recruiting
Phase 2

Lacripep for Corneal Wound Healing Study

Corneal Epithelial Wound Healing
Henry M. Jackson Foundation for the Advancement of Military Medicine88 enrolled1 locationNCT06854393
Recruiting
Phase 3

AURN001 Efficacy in Participants With Corneal Edema Secondary to Corneal Endothelial Dysfunction

Corneal EdemaCorneal Endothelial DysfunctionFuchs Endothelial Corneal Dysfunction+1 more
Aurion Biotech120 enrolled12 locationsNCT07368959
Recruiting
Not Applicable

Losartan for Corneal Fibrosis

Corneal Scarring Fibrosis
Universidad Autonoma de Nuevo Leon46 enrolled1 locationNCT07449000
Recruiting

Data Gathering for A10900

HealthyRetinal DiseaseGlaucoma+1 more
Optos, PLC180 enrolled4 locationsNCT07149740
Recruiting
Phase 3

Comparison of Epi-ON Corneal Collagen Crosslinking Performed Using an 18-Minute UVA Exposure vs. a 24-Minute UVA Exposure on Eyes With Ectatic Corneal Diseases

KeratoconusEctasia of CorneaPellucid Marginal Corneal Degeneration+1 more
Woolfson Eye Institute485 enrolled12 locationsNCT07124910
Recruiting
Phase 2

Efficacy of Topical Mesenchymal Stromal Cell Secretome for Ocular Surface Disease

Persistent Corneal Epithelial DefectCorneal Epithelial Disorders
University of Illinois at Chicago24 enrolled1 locationNCT06919081
Recruiting
Not Applicable

4D Duke Microscope Integrated Optical Coherence Tomography in a Zeiss Artevo 800

Corneal Diseases
Duke University5 enrolled1 locationNCT07024719
Recruiting

Performance Evaluation of Dream OCT: AP Study

Glaucoma PatientsRetina PatientsEyes With Corneal Abnormality+1 more
Intalight, Inc120 enrolled1 locationNCT07355491
Recruiting
Phase 1

PVEK Corneal Implant For Treatment of Corneal Edema

Pseudophakic Bullous KeratopathyFuchs' Endothelial DystrophyCorneal Edema+1 more
Precise Bio15 enrolled3 locationsNCT07325097
Recruiting
Not Applicable

Conjunctival Transpositional Surgery for Primary Pterygium

Pterygium of the Conjunctiva and Cornea
Zahedan University of Medical Sciences70 enrolled1 locationNCT07343011
Recruiting
Phase 1Phase 2

Clinical Study of Intrastromal Anti-VEGF Injection for Corneal Neovascularization.

Herpes Simplex KeratitisCorneal Neovascularization
Second Affiliated Hospital, School of Medicine, Zhejiang University100 enrolled1 locationNCT07329686
Recruiting
Phase 2

ExCrossV Multi Site Trial for Vascularized High Risk Keratoplasty

Corneal Transplant Failure
Massachusetts Eye and Ear Infirmary96 enrolled12 locationsNCT06753916
Recruiting

fMRI and IVCM Cornea Microscopy of CXL in Keratoconus

Pain, ChronicPain, PostoperativePain, Acute+5 more
Boston Children's Hospital60 enrolled1 locationNCT04439552
Recruiting
Not Applicable

Clinical Outcomes of the Gore Synthetic Cornea Device

Corneal Opacity
W.L.Gore & Associates10 enrolled2 locationsNCT06174376
Recruiting

Limbal Stem Cell Deficiency of Genetic Origin: Genotype-phenotype Correlation

Limbus Corneae
Fondation Ophtalmologique Adolphe de Rothschild60 enrolled1 locationNCT02886611
Recruiting
Phase 1

Safety and Tolerability of EO2002

Endothelial Cell Loss, CornealCataract
Asociación para Evitar la Ceguera en México32 enrolled1 locationNCT05587205
Recruiting
Phase 1

Study to Assess Safety and Tolerability of Multiple Doses of EO2002

Endothelial DysfunctionPseudophakic Bullous KeratopathyFuchs' Endothelial Dystrophy+5 more
Asociación para Evitar la Ceguera en México12 enrolled1 locationNCT05636579
Recruiting
Not Applicable

High Resolution, High-speed Multimodal Ophthalmic Imaging

HypertensionStrokeDiabetes+12 more
Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts1,200 enrolled1 locationNCT04129021
Recruiting

Corneal Elastography and Patient Specific Modeling

Cornea; Ectasia
The Cleveland Clinic60 enrolled1 locationNCT03030755