Cornea Clinical Trials

87 recruitingLast updated: May 21, 2026

There are 87 actively recruiting cornea clinical trials across 27 countries. Studies span Not Applicable, Phase 2, Phase 1, Phase 3, Early Phase 1, Phase 4. Top locations include Indianapolis, Indiana, United States, Boston, Massachusetts, United States, Portland, Oregon, United States. Updated daily from ClinicalTrials.gov.


Cornea Trials at a Glance

87 actively recruiting trials for cornea are listed on ClinicalTrialsFinder across 6 cities in 27 countries. The largest study group is Not Applicable with 26 trials, with the heaviest enrollment activity in Indianapolis, Boston, and Portland. Lead sponsors running cornea studies include Singapore Eye Research Institute, Centre hospitalier de l'Université de Montréal (CHUM), and Eye & ENT Hospital of Fudan University.

About Cornea Clinical Trials

Looking for clinical trials for Cornea? There are currently 5 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Cornea trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Cornea clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 87 trials

Recruiting
Not Applicable

Follow-up Compliance for Corneal Ulcer Patients With SMS Reminder

corneal ulcer
Seva Canada Society310 enrolled1 locationNCT07377513
Recruiting

Acute Ocular Effects of Cigarette Smoking

Smoking, CigaretteCorneaAnterior Eye Segment Measurements
Istanbul University90 enrolled1 locationNCT07580040
Recruiting

Analysis of the Genotype/Phenotype Relationship in the Fuchs' Corneal Endothelial Dystrophy in France

Corneal Dystrophies
Centre Hospitalier Universitaire de Saint Etienne500 enrolled1 locationNCT05742321
Recruiting
Not Applicable

Losartan for Corneal Fibrosis

Corneal Scarring Fibrosis
Universidad Autonoma de Nuevo Leon46 enrolled1 locationNCT07449000
Recruiting

National Ophthalmic Genotyping and Phenotyping Network (eyeGENE (Registered Trademark)), Stage 3 - Expansion of DNA and Data Repositories for Rare Inherited Ophthalmic Diseases

AniridiaAlbinismCorneal Dystrophy+4 more
National Eye Institute (NEI)1,000 enrolled2 locationsNCT06491615
Recruiting
Phase 4

Comparison of Topical Insulin and Amniotic Membrane Transplant for Persistent Corneal Epithelial Defects

Persistent Corneal Epithelial Defect
Al-Shifa Trust Eye Hospital214 enrolled1 locationNCT07561398
Recruiting
Not Applicable

Evaluation of the Clinical Efficacy and Mechanisms of Cord Plasma Eye Drops in the Treatment of Neuropathic Corneal Pain

Neuropathic PainCorneal Disease
Singapore Eye Research Institute20 enrolled1 locationNCT07566806
Recruiting
Not Applicable

Corneal Collagen Crosslinking to Increase the Resistance of the Support Graft of the KPro Type I Against Corneal Melting

Corneal Melting in Boston Keratoprosthesis Type I
Centre hospitalier de l'Université de Montréal (CHUM)40 enrolled1 locationNCT03041883
Recruiting
Not Applicable

The Role of Transscleral Cyclophotocoagulation in Patients Undergoing a Boston Keratoprosthesis

GlaucomaEye DiseasesCornea Disease
Centre hospitalier de l'Université de Montréal (CHUM)20 enrolled1 locationNCT04232982
Recruiting

The German Keratoplasty Registry of the German Ophthalmological Society (DOG)

Corneal Transplantation
Universität des Saarlandes100,000 enrolled1 locationNCT03381794
Recruiting

Analysis of Influencing Factors of High-Order Aberrations of SMILE With Lenticule Retained

Small-incision Lenticule Extraction (SMILE) SurgeryCorneal Higher-order Wavefront AberrationsResidual Lenticule
Second Affiliated Hospital of Nanchang University33 enrolled1 locationNCT06806085
Recruiting
Phase 2

ExCrossV Multi Site Trial for Vascularized High Risk Keratoplasty

Corneal Transplant Failure
Massachusetts Eye and Ear Infirmary96 enrolled12 locationsNCT06753916
Recruiting
Phase 3

AURN001 Efficacy in Participants With Corneal Edema Secondary to Corneal Endothelial Dysfunction

Corneal EdemaCorneal Endothelial DysfunctionFuchs Endothelial Corneal Dysfunction+1 more
Aurion Biotech120 enrolled12 locationsNCT07368959
Recruiting
Not Applicable

Plasma Rich in Growth Factors in Corneal Endothelial Transplantation

Fuchs' Endothelial DystrophyCorneal Edema
University of Miami100 enrolled2 locationsNCT06261346
Recruiting
Phase 1

Study to Evaluate the Safety and Efficacy of CSB-001 Ophthalmic Solution 0.1% in Subjects With Corneal Scars

Corneal Scar
Claris Biotherapeutics, Inc.20 enrolled7 locationsNCT06257355
Recruiting
Not Applicable

The Belgian Endothelial Surgical Transplant of the Cornea

Pseudophakic Bullous KeratopathyFuchs' Endothelial DystrophyCorneal Edema+2 more
University Hospital, Antwerp220 enrolled11 locationsNCT05436665
Recruiting
Phase 2

Lacripep for Corneal Wound Healing Study

Corneal Epithelial Wound Healing
Henry M. Jackson Foundation for the Advancement of Military Medicine88 enrolled1 locationNCT06854393
Recruiting

Data Gathering for A10900

HealthyRetinal DiseaseGlaucoma+1 more
Optos, PLC180 enrolled4 locationsNCT07149740
Recruiting
Not Applicable

Intrastromal Moxifloxacin as an Adjunctive Therapy in Recalcitrant Bacterial Keratitis

Bacterial Keratitiscorneal ulcerRecalcitrant Infectious Keratitis
Minia University60 enrolled1 locationNCT07394257
Recruiting
Phase 3

Comparison of Epi-ON Corneal Collagen Crosslinking Performed Using an 18-Minute UVA Exposure vs. a 24-Minute UVA Exposure on Eyes With Ectatic Corneal Diseases

KeratoconusEctasia of CorneaPellucid Marginal Corneal Degeneration+1 more
Woolfson Eye Institute485 enrolled12 locationsNCT07124910