Cornea Clinical Trials

94 recruitingLast updated: July 25, 2026

There are 94 actively recruiting cornea clinical trials across 34 countries. Studies span Not Applicable, Phase 2, Phase 1, Phase 3, Early Phase 1, Phase 4. Top locations include Boston, Massachusetts, United States, Indianapolis, Indiana, United States, Portland, Oregon, United States. Updated daily from ClinicalTrials.gov.


Cornea Trials at a Glance

94 actively recruiting trials for cornea are listed on ClinicalTrialsFinder across 6 cities in 34 countries. The largest study group is Not Applicable with 29 trials, with the heaviest enrollment activity in Boston, Indianapolis, and Portland. Lead sponsors running cornea studies include Singapore Eye Research Institute, Centre hospitalier de l'Université de Montréal (CHUM), and Eye & ENT Hospital of Fudan University.

Treatments under study

About Cornea Clinical Trials

Looking for clinical trials for Cornea? There are currently 6 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Cornea trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Cornea clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 94 trials

Recruiting
Phase 3

An Efficacy and Safety Study of Cenegermin Ophthalmic Solution Compared With Vehicle in the Treatment of PCED

Persistent Corneal Epithelial Defect
Dompé Farmaceutici S.p.A150 enrolled77 locationsNCT07519902
Recruiting
Phase 1

Simple Non-cultured Endothelial Cell Therapy for Corneal Endothelial Dysfunction

Bullous KeratopathyCorneal Endothelial Dystrophy
Singapore Eye Research Institute20 enrolled1 locationNCT07711561
Recruiting
Not Applicable

A Single-Center Clinical Study to Evaluate the Efficacy and Safety of Autologous Urine-Derived Epithelial Cells in the Treatment of Corneal Endothelial Cell Dysfunction

Cornea Disease
Suxia Li3 enrolled1 locationNCT07435142
Recruiting

Prognosis of Posterior Lamellar Keratoplasty

Pseudophakic Bullous KeratopathyFuchs' Endothelial Corneal Dystrophy
Centre Hospitalier Régional Metz-Thionville1,000 enrolled1 locationNCT06859411
Recruiting

Development of a Mobile Terminal-Based Intelligent Detection System for Multiple Anterior Segment Diseases of the Eye

pterygiumCataractBlepharitis+13 more
Zhongshan Ophthalmic Center, Sun Yat-sen University3,000 enrolled1 locationNCT07634913
Recruiting

National Ophthalmic Genotyping and Phenotyping Network (eyeGENE (Registered Trademark)), Stage 3 - Expansion of DNA and Data Repositories for Rare Inherited Ophthalmic Diseases

AniridiaAlbinismCorneal Dystrophy+4 more
National Eye Institute (NEI)1,000 enrolled2 locationsNCT06491615
Recruiting
Not Applicable

Fine-needle Diathermy Combined With Subconjunctival Bevacizumab for Corneal Neovascularization

Corneal Neovascularisation
HoChiMinh City Eye Hospital51 enrolled1 locationNCT07642960
Recruiting
Phase 3

Fungal Ulcer Treatment Augmented With Natamycin and Cyclosporine A

corneal ulcerFungal Keratitis
University of California, San Francisco150 enrolled2 locationsNCT06658002
Recruiting

Corneal Elastography and Patient Specific Modeling

KeratoconusCornea; EctasiaRefractive errors
The Cleveland Clinic60 enrolled1 locationNCT03030755
Recruiting
Early Phase 1

Suture Lid Spring for Lid Closure in Patients With Facial Nerve Palsy

Paralytic LagophthalmosCorneal ExposureFacial Nerve Palsy
University of Alberta10 enrolled2 locationsNCT06895902
Recruiting

Impact of GLP-1 Receptor Agonists on Dry Eye Disease in Patients With Type 2 Diabetes Mellitus and Obesity

Dry Eye Disease (DED)Diabetes Type 2Diabete Mellitus+3 more
Attikon Hospital100 enrolled1 locationNCT07605572
Recruiting
Not Applicable

Effect of Descemet Membrane Polishing in Fuchs Endothelial Corneal Dystrophy

Fuchs' Endothelial Corneal Dystrophy
Centre Hospitalier Universitaire de Saint Etienne20 enrolled5 locationsNCT07539012
Recruiting
Phase 3

AURN001 Efficacy in Participants With Corneal Edema Secondary to Corneal Endothelial Dysfunction

Corneal EdemaCorneal Endothelial DysfunctionFuchs Endothelial Corneal Dysfunction+1 more
Aurion Biotech120 enrolled12 locationsNCT07368959
Recruiting
Not Applicable

Self-Adhering Magnetic Device to Treat Corneal Exposure

Paralytic LagophthalmosCorneal Exposure
University of Illinois at Chicago25 enrolled1 locationNCT06291818
Recruiting
Not Applicable

Follow-up Compliance for Corneal Ulcer Patients With SMS Reminder

corneal ulcer
Seva Canada Society310 enrolled1 locationNCT07377513
Recruiting

Analysis of the Genotype/Phenotype Relationship in the Fuchs' Corneal Endothelial Dystrophy in France

Corneal Dystrophies
Centre Hospitalier Universitaire de Saint Etienne500 enrolled1 locationNCT05742321
Recruiting

Acute Ocular Effects of Cigarette Smoking

Smoking, CigaretteCorneaAnterior Eye Segment Measurements
Istanbul University90 enrolled1 locationNCT07580040
Recruiting
Not Applicable

Losartan for Corneal Fibrosis

Corneal Scarring Fibrosis
Universidad Autonoma de Nuevo Leon46 enrolled1 locationNCT07449000
Recruiting
Phase 4

Comparison of Topical Insulin and Amniotic Membrane Transplant for Persistent Corneal Epithelial Defects

Persistent Corneal Epithelial Defect
Al-Shifa Trust Eye Hospital214 enrolled1 locationNCT07561398
Recruiting
Not Applicable

Evaluation of the Clinical Efficacy and Mechanisms of Cord Plasma Eye Drops in the Treatment of Neuropathic Corneal Pain

Neuropathic PainCorneal Disease
Singapore Eye Research Institute20 enrolled1 locationNCT07566806