Coronary Arterial Disease Clinical Trials

52 recruitingLast updated: July 25, 2026

There are 52 actively recruiting coronary arterial disease clinical trials across 32 countries. Studies span Not Applicable, Phase 4, Phase 2. Top locations include Beijing, Beijing Municipality, China, Jacksonville, Florida, United States, Bucharest, Romania. Updated daily from ClinicalTrials.gov.


Coronary Arterial Disease Trials at a Glance

52 actively recruiting trials for coronary arterial disease are listed on ClinicalTrialsFinder across 6 cities in 32 countries. The largest study group is Not Applicable with 21 trials, with the heaviest enrollment activity in Beijing, Jacksonville, and Bucharest. Lead sponsors running coronary arterial disease studies include Kutahya Health Sciences University, University of Florida, and Tampere Heart Hospital.

Browse coronary arterial disease trials by phase

Treatments under study

About Coronary Arterial Disease Clinical Trials

Looking for clinical trials for Coronary Arterial Disease? There are currently 5 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Coronary Arterial Disease trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Coronary Arterial Disease clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 52 trials

Recruiting

Revascularization of Calcified Coronary Arteries

Coronary Arterial Disease (CAD)Percutaneous Coronary Intervention (PCI)Ischemic Heart Disease (IHD)
Aalborg University Hospital100 enrolled1 locationNCT07724184
Recruiting
Not Applicable

AGENT DCB STANCE: Safety and Effectiveness Study of AGENT Drug-Coated Balloon Compared to Standard of Care Percutaneous Coronary Intervention (PCI) Treatment for de Novo Coronary Lesions

Coronary Arterial Disease (CAD)de Novo Lesions in Native Coronary Arteries
Boston Scientific Corporation1,616 enrolled62 locationsNCT06959524
Recruiting
Not Applicable

Comparative Effectiveness of Dual Antihypertensive Regimens in Patients After Percutaneous Coronary Intervention

HypertensionPercutaneous Coronary InterventionCoronary Arterial Disease
National Medical Research Center for Therapy and Preventive Medicine207 enrolled1 locationNCT07683585
Recruiting
Not Applicable

ShockFast Intravascular Lithotripsy Device for Treatment of Calcified Coronary Lesions

Coronary Arterial DiseaseCalcified Coronary Artery Disease
Shunmei Medical120 enrolled11 locationsNCT07407738
Recruiting

Effect of Dapagliflozin on Right Ventricular-Pulmonary Artery Coupling After Off-Pump Coronary Atery Bypass Grafting

Heart FailureCoronary Arterial Disease
Pyatigorsk City Clinical Hospital Number 172 enrolled1 locationNCT07601867
Recruiting
Not Applicable

FORWARD CAD IDE Study

Coronary Arterial Disease (CAD)
Shockwave Medical, Inc.408 enrolled34 locationsNCT06662500
Recruiting

Artificial Intelligence Based Timing, Infarct Size and Outcomes in Acute Coronary Occlusion Myocardial Infarction

Coronary Arterial Disease (CAD)Acute Coronary Syndrome (ACS) Undergoing Percutaneous Coronary Intervention (PCI)
Azienda Ospedaliera di Bolzano1,500 enrolled1 locationNCT06910436
Recruiting

OPtimal stEnt Deployment stRategy oF Contemporary sTents - Registry to Evaluate Percutaneous Coronary Intervention Using Bioresorbable Scaffolds With Thinner-strut Construction and Guidance by intracOronary Imaging to REduce Scaffold Failure

Coronary Arterial Disease (CAD)Percutaneous Coronary Intervention (PCI)
Albert Schweitzer Ziekenhuis, Netherlands117 enrolled1 locationNCT06919562
Recruiting
Not Applicable

AVS Pulse Intravascular Lithotripsy™ (Pulse IVL™) to Open Vessels With Calcific Walls and Enhance Vascular Compliance and Remodeling for Coronary Artery Disease

Coronary Arterial Disease (CAD)
Amplitude Vascular Systems, Inc.15 enrolled2 locationsNCT07510438
Recruiting
Not Applicable

ESPB vs SPSIP for Postoperative Analgesia After CABG

Postoperative Pain ManagementCoronary Arterial DiseaseCoronary Artery Bypass Grafting (CABG) Surgery
Kutahya Health Sciences University64 enrolled1 locationNCT07388745
Recruiting
Phase 4

The Bridging Antiplatelet Therapy With Cangrelor 2 Study

Coronary Arterial Disease (CAD)
University of Florida50 enrolled1 locationNCT07225842
Recruiting
Not Applicable

Prolonged Chest Tube Treatment to Reduce Rates of Atrial Fibrillation Following Cardiac Surgery

Coronary Arterial Disease (CAD)Valve ReplacementAortic Surgery
Region Skane624 enrolled1 locationNCT06800781
Recruiting
Not Applicable

Orbital Atherectomy vs Intravascular Lithotripsy for the Treatment of Calcified Coronary Nodules (ORBIT-SHOCK).

Chronic Coronary SyndromeCoronary Arterial Disease (CAD)Percutaneous Coronary Intervention (PCI)+6 more
Spanish Society of Cardiology50 enrolled6 locationsNCT06736665
Recruiting

Restrospective Analysis of MACE in Patients Treated With Drug-elluting Balloons.

Coronary Arterial Disease (CAD)Bifurcation Coronary DiseaseRestenosis, Coronary
Olivier F. Bertrand1,500 enrolled1 locationNCT06972225
Recruiting
Not Applicable

Intracoronary Cryotherapy Effect on Stabilization of Vulnerable Plaque in Patients With Stable Angina or ACS - A Traditional Feasibility Study

plaqueCryotherapy EffectCryotherapy+4 more
Cryotherapeutics SA30 enrolled3 locationsNCT06939374
Recruiting
Not Applicable

Super High-pressure Balloon Versus Intravascular Lithotripsy to Prepare Severely Calcified Coronary Lesions

Coronary Arterial Disease (CAD)PCICalcified Coronary Lesions
Nanjing First Hospital, Nanjing Medical University78 enrolled3 locationsNCT07093788
Recruiting

Safety and Effectiveness of the Crystalline Sirolimus-Eluting Device in Patients With Coronary Artery Disease

Coronary Arterial Disease (CAD)ST Elevation Myocardial InfarctionSilent Ischemia+3 more
Fundación Interhospitalaria para la Investigación Cardiovascular FIC1,118 enrolled1 locationNCT07444957
Recruiting

Validation of Sudden Cardiac Arrest Risk Factors in Patients With CAD

Sudden Cardiac DeathCoronary Arterial Disease (CAD)Sudden Cardiac Arrest
Tampere Heart Hospital1,500 enrolled3 locationsNCT07444931
Recruiting
Phase 4

Prasugrel Monotherapy Reduced Dose in Acute and Chronic Coronary Syndrome Patients After Percutaneous Coronary Intervention (PROMOTE)

Coronary Arterial Disease (CAD)Percutaneous Coronary Intervention (PCI)
J.P.S Henriques300 enrolled1 locationNCT06916520
Recruiting
Phase 4

The Switching Antiplatelet-9 (SWAP-9) Study

Coronary Arterial Disease (CAD)
University of Florida90 enrolled1 locationNCT06588595